| Title : Carboxylesterase-2 plays a critical role in dabigatran etexilate active metabolite formation - Laizure_2022_Drug.Metab.Pharmacokinet_47_100479 |
| Author(s) : Laizure SC , Chen F , Farrar JE , Ali D , Yang B , Parker RB |
| Ref : Drug Metab Pharmacokinet , 47 :100479 , 2022 |
| Abstract : |
| PubMedSearch : Laizure_2022_Drug.Metab.Pharmacokinet_47_100479 |
| PubMedID: 36375226 |
| Title : Alcohol inhibits the metabolism of dimethyl fumarate to the active metabolite responsible for decreasing relapse frequency in the treatment of multiple sclerosis - Yang_2022_PLoS.One_17_e0278111 |
| Author(s) : Yang B , Parker RB , Meibohm B , Temrikar ZH , Srivastava A , Laizure SC |
| Ref : PLoS ONE , 17 :e0278111 , 2022 |
| Abstract : |
| PubMedSearch : Yang_2022_PLoS.One_17_e0278111 |
| PubMedID: 36441753 |
| Title : Is Genetic Variability in Carboxylesterase-1 and Carboxylesterase-2 Drug Metabolism an Important Component of Personalized Medicine? - Laizure_2020_Xenobiotica_50_92 |
| Author(s) : Laizure SC , Parker RB |
| Ref : Xenobiotica , 50 :92 , 2020 |
| Abstract : |
| PubMedSearch : Laizure_2020_Xenobiotica_50_92 |
| PubMedID: 31601149 |
| Title : Inhibition of Carboxylesterase-1 Alters Clopidogrel Metabolism and Disposition - Laizure_2020_Xenobiotica_50_245 |
| Author(s) : Laizure SC , Hu ZY , Potter PM , Parker RB |
| Ref : Xenobiotica , 50 :245 , 2020 |
| Abstract : |
| PubMedSearch : Laizure_2020_Xenobiotica_50_245 |
| PubMedID: 31039046 |
| Title : Clinical implications of genetic variation in carboxylesterase drug metabolism - Chen_2018_Expert.Opin.Drug.Metab.Toxicol_14_131 |
| Author(s) : Chen F , Zhang B , Parker RB , Laizure SC |
| Ref : Expert Opin Drug Metab Toxicol , 14 :131 , 2018 |
| Abstract : |
| PubMedSearch : Chen_2018_Expert.Opin.Drug.Metab.Toxicol_14_131 |
| PubMedID: 29264996 |
| Gene_locus related to this paper: human-CES1 , human-CES2 |
| Title : Alterations of drug-metabolizing enzymes and transporters under diabetic conditions: what is the potential clinical significance? - Chen_2018_Drug.Metab.Rev__1 |
| Author(s) : Chen F , Li DY , Zhang B , Sun JY , Sun F , Ji X , Qiu JC , Parker RB , Laizure SC , Xu J |
| Ref : Drug Metabolism Reviews , :1 , 2018 |
| Abstract : |
| PubMedSearch : Chen_2018_Drug.Metab.Rev__1 |
| PubMedID: 30221555 |
| Title : Effects of alcohol on human carboxylesterase drug metabolism - Parker_2015_Clin.Pharmacokinet_54_627 |
| Author(s) : Parker RB , Hu ZY , Meibohm B , Laizure SC |
| Ref : Clinical Pharmacokinetics , 54 :627 , 2015 |
| Abstract : |
| PubMedSearch : Parker_2015_Clin.Pharmacokinet_54_627 |
| PubMedID: 25511794 |
| Title : Identification of carboxylesterase-dependent dabigatran etexilate hydrolysis - Laizure_2014_Drug.Metab.Dispos_42_201 |
| Author(s) : Laizure SC , Parker RB , Herring VL , Hu ZY |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 42 :201 , 2014 |
| Abstract : |
| PubMedSearch : Laizure_2014_Drug.Metab.Dispos_42_201 |
| PubMedID: 24212379 |
| Gene_locus related to this paper: human-CES1 |
| Title : Physiologically based pharmacokinetic modeling of impaired carboxylesterase-1 activity: effects on oseltamivir disposition - Hu_2014_Clin.Pharmacokinet_53_825 |
| Author(s) : Hu ZY , Edginton AN , Laizure SC , Parker RB |
| Ref : Clinical Pharmacokinetics , 53 :825 , 2014 |
| Abstract : |
| PubMedSearch : Hu_2014_Clin.Pharmacokinet_53_825 |
| PubMedID: 25103325 |
| Title : The role of human carboxylesterases in drug metabolism: have we overlooked their importance? - Laizure_2013_Pharmacotherapy_33_210 |
| Author(s) : Laizure SC , Herring V , Hu Z , Witbrodt K , Parker RB |
| Ref : Pharmacotherapy , 33 :210 , 2013 |
| Abstract : |
| PubMedSearch : Laizure_2013_Pharmacotherapy_33_210 |
| PubMedID: 23386599 |
| Title : The effect of ethanol on oral cocaine pharmacokinetics reveals an unrecognized class of ethanol-mediated drug interactions - Parker_2010_Drug.Metab.Dispos_38_317 |
| Author(s) : Parker RB , Laizure SC |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 38 :317 , 2010 |
| Abstract : |
| PubMedSearch : Parker_2010_Drug.Metab.Dispos_38_317 |
| PubMedID: 19920055 |
| Title : A comparison of the metabolism of clopidogrel and prasugrel - Laizure_2010_Expert.Opin.Drug.Metab.Toxicol_6_1417 |
| Author(s) : Laizure SC , Parker RB |
| Ref : Expert Opin Drug Metab Toxicol , 6 :1417 , 2010 |
| Abstract : |
| PubMedSearch : Laizure_2010_Expert.Opin.Drug.Metab.Toxicol_6_1417 |
| PubMedID: 20839914 |