Parker RB

References (12)

Title : Carboxylesterase-2 plays a critical role in dabigatran etexilate active metabolite formation - Laizure_2022_Drug.Metab.Pharmacokinet_47_100479
Author(s) : Laizure SC , Chen F , Farrar JE , Ali D , Yang B , Parker RB
Ref : Drug Metab Pharmacokinet , 47 :100479 , 2022
Abstract :
PubMedSearch : Laizure_2022_Drug.Metab.Pharmacokinet_47_100479
PubMedID: 36375226

Title : Alcohol inhibits the metabolism of dimethyl fumarate to the active metabolite responsible for decreasing relapse frequency in the treatment of multiple sclerosis - Yang_2022_PLoS.One_17_e0278111
Author(s) : Yang B , Parker RB , Meibohm B , Temrikar ZH , Srivastava A , Laizure SC
Ref : PLoS ONE , 17 :e0278111 , 2022
Abstract :
PubMedSearch : Yang_2022_PLoS.One_17_e0278111
PubMedID: 36441753

Title : Is Genetic Variability in Carboxylesterase-1 and Carboxylesterase-2 Drug Metabolism an Important Component of Personalized Medicine? - Laizure_2020_Xenobiotica_50_92
Author(s) : Laizure SC , Parker RB
Ref : Xenobiotica , 50 :92 , 2020
Abstract :
PubMedSearch : Laizure_2020_Xenobiotica_50_92
PubMedID: 31601149

Title : Inhibition of Carboxylesterase-1 Alters Clopidogrel Metabolism and Disposition - Laizure_2020_Xenobiotica_50_245
Author(s) : Laizure SC , Hu ZY , Potter PM , Parker RB
Ref : Xenobiotica , 50 :245 , 2020
Abstract :
PubMedSearch : Laizure_2020_Xenobiotica_50_245
PubMedID: 31039046

Title : Alterations of drug-metabolizing enzymes and transporters under diabetic conditions: what is the potential clinical significance? - Chen_2018_Drug.Metab.Rev__1
Author(s) : Chen F , Li DY , Zhang B , Sun JY , Sun F , Ji X , Qiu JC , Parker RB , Laizure SC , Xu J
Ref : Drug Metabolism Reviews , :1 , 2018
Abstract :
PubMedSearch : Chen_2018_Drug.Metab.Rev__1
PubMedID: 30221555

Title : Clinical implications of genetic variation in carboxylesterase drug metabolism - Chen_2018_Expert.Opin.Drug.Metab.Toxicol_14_131
Author(s) : Chen F , Zhang B , Parker RB , Laizure SC
Ref : Expert Opin Drug Metab Toxicol , 14 :131 , 2018
Abstract :
PubMedSearch : Chen_2018_Expert.Opin.Drug.Metab.Toxicol_14_131
PubMedID: 29264996
Gene_locus related to this paper: human-CES1 , human-CES2

Title : Effects of alcohol on human carboxylesterase drug metabolism - Parker_2015_Clin.Pharmacokinet_54_627
Author(s) : Parker RB , Hu ZY , Meibohm B , Laizure SC
Ref : Clinical Pharmacokinetics , 54 :627 , 2015
Abstract :
PubMedSearch : Parker_2015_Clin.Pharmacokinet_54_627
PubMedID: 25511794

Title : Physiologically based pharmacokinetic modeling of impaired carboxylesterase-1 activity: effects on oseltamivir disposition - Hu_2014_Clin.Pharmacokinet_53_825
Author(s) : Hu ZY , Edginton AN , Laizure SC , Parker RB
Ref : Clinical Pharmacokinetics , 53 :825 , 2014
Abstract :
PubMedSearch : Hu_2014_Clin.Pharmacokinet_53_825
PubMedID: 25103325

Title : Identification of carboxylesterase-dependent dabigatran etexilate hydrolysis - Laizure_2014_Drug.Metab.Dispos_42_201
Author(s) : Laizure SC , Parker RB , Herring VL , Hu ZY
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 42 :201 , 2014
Abstract :
PubMedSearch : Laizure_2014_Drug.Metab.Dispos_42_201
PubMedID: 24212379
Gene_locus related to this paper: human-CES1

Title : The role of human carboxylesterases in drug metabolism: have we overlooked their importance? - Laizure_2013_Pharmacotherapy_33_210
Author(s) : Laizure SC , Herring V , Hu Z , Witbrodt K , Parker RB
Ref : Pharmacotherapy , 33 :210 , 2013
Abstract :
PubMedSearch : Laizure_2013_Pharmacotherapy_33_210
PubMedID: 23386599

Title : The effect of ethanol on oral cocaine pharmacokinetics reveals an unrecognized class of ethanol-mediated drug interactions - Parker_2010_Drug.Metab.Dispos_38_317
Author(s) : Parker RB , Laizure SC
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 38 :317 , 2010
Abstract :
PubMedSearch : Parker_2010_Drug.Metab.Dispos_38_317
PubMedID: 19920055

Title : A comparison of the metabolism of clopidogrel and prasugrel - Laizure_2010_Expert.Opin.Drug.Metab.Toxicol_6_1417
Author(s) : Laizure SC , Parker RB
Ref : Expert Opin Drug Metab Toxicol , 6 :1417 , 2010
Abstract :
PubMedSearch : Laizure_2010_Expert.Opin.Drug.Metab.Toxicol_6_1417
PubMedID: 20839914