| Title : From the dual function lead AP2238 to AP2469, a multi-target-directed ligand for the treatment of Alzheimer's disease - Tarozzi_2014_Pharmacol.Res.Perspect_2_e00023 |
| Author(s) : Tarozzi A , Bartolini M , Piazzi L , Valgimigli L , Amorati R , Bolondi C , Djemil A , Mancini F , Andrisano V , Rampa A |
| Ref : Pharmacol Res Perspect , 2 :e00023 , 2014 |
| Abstract : |
| PubMedSearch : Tarozzi_2014_Pharmacol.Res.Perspect_2_e00023 |
| PubMedID: 25505579 |
| Title : Targeting Alzheimer's disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238 - Rizzo_2010_Bioorg.Med.Chem_18_1749 |
| Author(s) : Rizzo S , Bartolini M , Ceccarini L , Piazzi L , Gobbi S , Cavalli A , Recanatini M , Andrisano V , Rampa A |
| Ref : Bioorganic & Medicinal Chemistry , 18 :1749 , 2010 |
| Abstract : |
| PubMedSearch : Rizzo_2010_Bioorg.Med.Chem_18_1749 |
| PubMedID: 20171894 |
| Title : Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors - Belluti_2009_Eur.J.Med.Chem_44_1341 |
| Author(s) : Belluti F , Piazzi L , Bisi A , Gobbi S , Bartolini M , Cavalli A , Valenti P , Rampa A |
| Ref : Eur Journal of Medicinal Chemistry , 44 :1341 , 2009 |
| Abstract : |
| PubMedSearch : Belluti_2009_Eur.J.Med.Chem_44_1341 |
| PubMedID: 18396354 |
| Title : Benzofuran-based hybrid compounds for the inhibition of cholinesterase activity, beta amyloid aggregation, and abeta neurotoxicity - Rizzo_2008_J.Med.Chem_51_2883 |
| Author(s) : Rizzo S , Riviere C , Piazzi L , Bisi A , Gobbi S , Bartolini M , Andrisano V , Morroni F , Tarozzi A , Monti JP , Rampa A |
| Ref : Journal of Medicinal Chemistry , 51 :2883 , 2008 |
| Abstract : |
| PubMedSearch : Rizzo_2008_J.Med.Chem_51_2883 |
| PubMedID: 18419109 |
| Title : Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds - Piazzi_2008_Bioorg.Med.Chem.Lett_18_423 |
| Author(s) : Piazzi L , Cavalli A , Colizzi F , Belluti F , Bartolini M , Mancini F , Recanatini M , Andrisano V , Rampa A |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :423 , 2008 |
| Abstract : |
| PubMedSearch : Piazzi_2008_Bioorg.Med.Chem.Lett_18_423 |
| PubMedID: 17998161 |
| Title : Cholinesterase inhibitors: SAR and enzyme inhibitory activity of 3-[omega-(benzylmethylamino)alkoxy]xanthen-9-ones - Piazzi_2007_Bioorg.Med.Chem_15_575 |
| Author(s) : Piazzi L , Belluti F , Bisi A , Gobbi S , Rizzo S , Bartolini M , Andrisano V , Recanatini M , Rampa A |
| Ref : Bioorganic & Medicinal Chemistry , 15 :575 , 2007 |
| Abstract : |
| PubMedSearch : Piazzi_2007_Bioorg.Med.Chem_15_575 |
| PubMedID: 17008100 |
| Title : Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives - Piazzi_2007_J.Med.Chem_50_4250 |
| Author(s) : Piazzi L , Cavalli A , Belluti F , Bisi A , Gobbi S , Rizzo S , Bartolini M , Andrisano V , Recanatini M , Rampa A |
| Ref : Journal of Medicinal Chemistry , 50 :4250 , 2007 |
| Abstract : |
| PubMedSearch : Piazzi_2007_J.Med.Chem_50_4250 |
| PubMedID: 17655212 |
| Title : Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation - Belluti_2005_J.Med.Chem_48_4444 |
| Author(s) : Belluti F , Rampa A , Piazzi L , Bisi A , Gobbi S , Bartolini M , Andrisano V , Cavalli A , Recanatini M , Valenti P |
| Ref : Journal of Medicinal Chemistry , 48 :4444 , 2005 |
| Abstract : |
| PubMedSearch : Belluti_2005_J.Med.Chem_48_4444 |
| PubMedID: 15974596 |
| Title : 3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy - Piazzi_2003_J.Med.Chem_46_2279 |
| Author(s) : Piazzi L , Rampa A , Bisi A , Gobbi S , Belluti F , Cavalli A , Bartolini M , Andrisano V , Valenti P , Recanatini M |
| Ref : Journal of Medicinal Chemistry , 46 :2279 , 2003 |
| Abstract : |
| PubMedSearch : Piazzi_2003_J.Med.Chem_46_2279 |
| PubMedID: 12773032 |
| Title : Acetylcholinesterase Inhibitors: SAR and Kinetic Studies on omega-[N-Methyl-N-(3-alkylcarbamoyloxyphenyl)methyl]aminoalkoxyaryl Derivatives - Rampa_2001_J.Med.Chem_44_3810 |
| Author(s) : Rampa A , Piazzi L , Belluti F , Gobbi S , Bisi A , Bartolini M , Andrisano V , Cavrini V , Cavalli A , Recanatini M , Valenti P |
| Ref : Journal of Medicinal Chemistry , 44 :3810 , 2001 |
| Abstract : |
| PubMedSearch : Rampa_2001_J.Med.Chem_44_3810 |
| PubMedID: 11689067 |
| Title : SAR of 9-amino-1,2,3,4-tetrahydroacridine-based acetylcholinesterase inhibitors: synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analogues - Recanatini_2000_J.Med.Chem_43_2007 |
| Author(s) : Recanatini M , Cavalli A , Belluti F , Piazzi L , Rampa A , Bisi A , Gobbi S , Valenti P , Andrisano V , Bartolini M , Cavrini V |
| Ref : Journal of Medicinal Chemistry , 43 :2007 , 2000 |
| Abstract : |
| PubMedSearch : Recanatini_2000_J.Med.Chem_43_2007 |
| PubMedID: 10821713 |