Recanatini M

References (25)

Title : Targeting Alzheimer's disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238 - Rizzo_2010_Bioorg.Med.Chem_18_1749
Author(s) : Rizzo S , Bartolini M , Ceccarini L , Piazzi L , Gobbi S , Cavalli A , Recanatini M , Andrisano V , Rampa A
Ref : Bioorganic & Medicinal Chemistry , 18 :1749 , 2010
Abstract :
PubMedSearch : Rizzo_2010_Bioorg.Med.Chem_18_1749
PubMedID: 20171894

Title : Structure-activity relationships and binding mode in the human acetylcholinesterase active site of pseudo-irreversible inhibitors related to xanthostigmine - Rizzo_2009_ChemMedChem_4_670
Author(s) : Rizzo S , Cavalli A , Ceccarini L , Bartolini M , Belluti F , Bisi A , Andrisano V , Recanatini M , Rampa A
Ref : ChemMedChem , 4 :670 , 2009
Abstract :
PubMedSearch : Rizzo_2009_ChemMedChem_4_670
PubMedID: 19222043

Title : Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of Diphenidol: novel M4 muscarinic receptor antagonists - Varoli_2008_Med.Chem_4_121
Author(s) : Varoli L , Angeli P , Buccioni M , Burnelli S , Fazio N , Marucci G , Recanatini M , Spampinato S
Ref : Med Chem , 4 :121 , 2008
Abstract :
PubMedSearch : Varoli_2008_Med.Chem_4_121
PubMedID: 18336331

Title : Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer - Tumiatti_2008_J.Med.Chem_51_7308
Author(s) : Tumiatti V , Milelli A , Minarini A , Rosini M , Bolognesi ML , Micco M , Andrisano V , Bartolini M , Mancini F , Recanatini M , Cavalli A , Melchiorre C
Ref : Journal of Medicinal Chemistry , 51 :7308 , 2008
Abstract :
PubMedSearch : Tumiatti_2008_J.Med.Chem_51_7308
PubMedID: 18954037

Title : The role of Li+, Na+, and K+ in the ligand binding inside the human acetylcholinesterase gorge - Petraglio_2008_Proteins_70_779
Author(s) : Petraglio G , Bartolini M , Branduardi D , Andrisano V , Recanatini M , Gervasio FL , Cavalli A , Parrinello M
Ref : Proteins , 70 :779 , 2008
Abstract :
PubMedSearch : Petraglio_2008_Proteins_70_779
PubMedID: 17729290

Title : Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds - Piazzi_2008_Bioorg.Med.Chem.Lett_18_423
Author(s) : Piazzi L , Cavalli A , Colizzi F , Belluti F , Bartolini M , Mancini F , Recanatini M , Andrisano V , Rampa A
Ref : Bioorganic & Medicinal Chemistry Lett , 18 :423 , 2008
Abstract :
PubMedSearch : Piazzi_2008_Bioorg.Med.Chem.Lett_18_423
PubMedID: 17998161

Title : Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives - Piazzi_2007_J.Med.Chem_50_4250
Author(s) : Piazzi L , Cavalli A , Belluti F , Bisi A , Gobbi S , Rizzo S , Bartolini M , Andrisano V , Recanatini M , Rampa A
Ref : Journal of Medicinal Chemistry , 50 :4250 , 2007
Abstract :
PubMedSearch : Piazzi_2007_J.Med.Chem_50_4250
PubMedID: 17655212

Title : Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer's disease - Bolognesi_2007_J.Med.Chem_50_6446
Author(s) : Bolognesi ML , Cavalli A , Valgimigli L , Bartolini M , Rosini M , Andrisano V , Recanatini M , Melchiorre C
Ref : Journal of Medicinal Chemistry , 50 :6446 , 2007
Abstract :
PubMedSearch : Bolognesi_2007_J.Med.Chem_50_6446
PubMedID: 18047264

Title : Cholinesterase inhibitors: SAR and enzyme inhibitory activity of 3-[omega-(benzylmethylamino)alkoxy]xanthen-9-ones - Piazzi_2007_Bioorg.Med.Chem_15_575
Author(s) : Piazzi L , Belluti F , Bisi A , Gobbi S , Rizzo S , Bartolini M , Andrisano V , Recanatini M , Rampa A
Ref : Bioorganic & Medicinal Chemistry , 15 :575 , 2007
Abstract :
PubMedSearch : Piazzi_2007_Bioorg.Med.Chem_15_575
PubMedID: 17008100

Title : Heterocyclic inhibitors of AChE acylation and peripheral sites - Bolognesi_2005_Farmaco_60_465
Author(s) : Bolognesi ML , Andrisano V , Bartolini M , Cavalli A , Minarini A , Recanatini M , Rosini M , Tumiatti V , Melchiorre C
Ref : Farmaco , 60 :465 , 2005
Abstract :
PubMedSearch : Bolognesi_2005_Farmaco_60_465
PubMedID: 15878569

Title : Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation - Belluti_2005_J.Med.Chem_48_4444
Author(s) : Belluti F , Rampa A , Piazzi L , Bisi A , Gobbi S , Bartolini M , Andrisano V , Cavalli A , Recanatini M , Valenti P
Ref : Journal of Medicinal Chemistry , 48 :4444 , 2005
Abstract :
PubMedSearch : Belluti_2005_J.Med.Chem_48_4444
PubMedID: 15974596

Title : A computational study of the binding of propidium to the peripheral anionic site of human acetylcholinesterase - Cavalli_2004_J.Med.Chem_47_3991
Author(s) : Cavalli A , Bottegoni G , Raco C , De Vivo M , Recanatini M
Ref : Journal of Medicinal Chemistry , 47 :3991 , 2004
Abstract :
PubMedSearch : Cavalli_2004_J.Med.Chem_47_3991
PubMedID: 15267237

Title : Acetylcholinesterase inhibitors as a starting point towards improved Alzheimer's disease therapeutics - Recanatini_2004_Curr.Pharm.Des_10_3157
Author(s) : Recanatini M , Valenti P
Ref : Curr Pharm Des , 10 :3157 , 2004
Abstract :
PubMedSearch : Recanatini_2004_Curr.Pharm.Des_10_3157
PubMedID: 15544505

Title : 3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy - Piazzi_2003_J.Med.Chem_46_2279
Author(s) : Piazzi L , Rampa A , Bisi A , Gobbi S , Belluti F , Cavalli A , Bartolini M , Andrisano V , Valenti P , Recanatini M
Ref : Journal of Medicinal Chemistry , 46 :2279 , 2003
Abstract :
PubMedSearch : Piazzi_2003_J.Med.Chem_46_2279
PubMedID: 12773032

Title : Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine - Tumiatti_2003_J.Med.Chem_46_954
Author(s) : Tumiatti V , Rosini M , Bartolini M , Cavalli A , Marucci G , Andrisano V , Angeli P , Banzi R , Minarini A , Recanatini M , Melchiorre C
Ref : Journal of Medicinal Chemistry , 46 :954 , 2003
Abstract :
PubMedSearch : Tumiatti_2003_J.Med.Chem_46_954
PubMedID: 12620072

Title : Synthesis and antagonistic activity at muscarinic receptor subtypes of some derivatives of diphenidol - Varoli_2003_Farmaco_58_651
Author(s) : Varoli L , Angeli P , Buccioni M , Burnelli S , Cavalli A , Marucci G , Recanatini M
Ref : Farmaco , 58 :651 , 2003
Abstract :
PubMedSearch : Varoli_2003_Farmaco_58_651
PubMedID: 13679157

Title : Determination of the dissociation constants (pKa) of basic acetylcholinesterase inhibitors by reversed-phase liquid chromatography - Bartolini_2002_J.Chromatogr.A_958_59
Author(s) : Bartolini M , Bertucci C , Gotti R , Tumiatti V , Cavalli A , Recanatini M , Andrisano V
Ref : Journal of Chromatography A , 958 :59 , 2002
Abstract :
PubMedSearch : Bartolini_2002_J.Chromatogr.A_958_59
PubMedID: 12134831

Title : Synthesis and Screening for Antiacetylcholinesterase Activity of (1-Benzyl-4-oxopiperidin-3-ylidene)methylindoles and -pyrroles Related to Donepezil - Andreani_2001_J.Med.Chem_44_4011
Author(s) : Andreani A , Cavalli A , Granaiola M , Guardigli M , Leoni A , Locatelli A , Morigi R , Rambaldi M , Recanatini M , Roda A
Ref : Journal of Medicinal Chemistry , 44 :4011 , 2001
Abstract :
PubMedSearch : Andreani_2001_J.Med.Chem_44_4011
PubMedID: 11689088

Title : Acetylcholinesterase Inhibitors: SAR and Kinetic Studies on omega-[N-Methyl-N-(3-alkylcarbamoyloxyphenyl)methyl]aminoalkoxyaryl Derivatives - Rampa_2001_J.Med.Chem_44_3810
Author(s) : Rampa A , Piazzi L , Belluti F , Gobbi S , Bisi A , Bartolini M , Andrisano V , Cavrini V , Cavalli A , Recanatini M , Valenti P
Ref : Journal of Medicinal Chemistry , 44 :3810 , 2001
Abstract :
PubMedSearch : Rampa_2001_J.Med.Chem_44_3810
PubMedID: 11689067

Title : SAR of 9-amino-1,2,3,4-tetrahydroacridine-based acetylcholinesterase inhibitors: synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analogues - Recanatini_2000_J.Med.Chem_43_2007
Author(s) : Recanatini M , Cavalli A , Belluti F , Piazzi L , Rampa A , Bisi A , Gobbi S , Valenti P , Andrisano V , Bartolini M , Cavrini V
Ref : Journal of Medicinal Chemistry , 43 :2007 , 2000
Abstract :
PubMedSearch : Recanatini_2000_J.Med.Chem_43_2007
PubMedID: 10821713

Title : [4-[[N-(3-chlorophenyl)carbamoyl]oxy]-2-butynyl]-trimethylammonium (McN-A-343)-related compounds. Effect of the butynyl chain inclusion into an aromatic unit on the potency for muscarinic receptors - Tumiatti_2000_Bioorg.Med.Chem_8_681
Author(s) : Tumiatti V , Angeli P , Andrisano V , Bolognesi ML , Cavalli A , Marucci G , Minarini A , Recanatini M , Rosini M , Melchiorre C
Ref : Bioorganic & Medicinal Chemistry , 8 :681 , 2000
Abstract :
PubMedSearch : Tumiatti_2000_Bioorg.Med.Chem_8_681
PubMedID: 10819156

Title : Acetylcholinesterase inhibitors for potential use in Alzheimer's disease: molecular modeling, synthesis and kinetic evaluation of 11H-indeno-[1,2-b]-quinolin-10-ylamine derivatives - Rampa_2000_Bioorg.Med.Chem_8_497
Author(s) : Rampa A , Bisi A , Belluti F , Gobbi S , Valenti P , Andrisano V , Cavrini V , Cavalli A , Recanatini M
Ref : Bioorganic & Medicinal Chemistry , 8 :497 , 2000
Abstract :
PubMedSearch : Rampa_2000_Bioorg.Med.Chem_8_497
PubMedID: 10732965

Title : Synthesis and antagonistic activity at muscarinic receptor subtypes of some 2-carbonyl derivatives of diphenidol - Varoli_1999_Bioorg.Med.Chem_7_1837
Author(s) : Varoli L , Angeli P , Burnelli S , Marucci G , Recanatini M
Ref : Bioorganic & Medicinal Chemistry , 7 :1837 , 1999
Abstract :
PubMedSearch : Varoli_1999_Bioorg.Med.Chem_7_1837
PubMedID: 10530931

Title : Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone for Potential Use against Alzheimer's Disease -
Author(s) : Melchiorre C , Andrisano V , Bolognesi ML , Budriesi R , Cavalli A , Cavrini V , Rosini M , Tumiatti V , Recanatini M
Ref : Journal of Medicinal Chemistry , 41 :4186 , 1998
PubMedID: 9784091

Title : Acetylcholinesterase Inhibitors: Synthesis and Structure-Activity Relationships of omega-[N-Methyl-N-(3-alkylcarbamoyloxyphenyl)- methyl]aminoalkoxyheteroaryl Derivatives - Rampa_1998_J.Med.Chem_41_3976
Author(s) : Rampa A , Bisi A , Valenti P , Recanatini M , Cavalli A , Andrisano V , Cavrini V , Fin L , Buriani A , Giusti P
Ref : Journal of Medicinal Chemistry , 41 :3976 , 1998
Abstract :
PubMedSearch : Rampa_1998_J.Med.Chem_41_3976
PubMedID: 9767635