| Title : Microtiter plate-based chemistry and in situ screening: SuFEx-enabled lead discovery of selective AChE inhibitors - Tang_2023_J.Enzyme.Inhib.Med.Chem_38_2237213 |
| Author(s) : Tang K , Li HH , Wu C , Zhang SL , Yang JG , Tang W , Qin HL |
| Ref : J Enzyme Inhib Med Chem , 38 :2237213 , 2023 |
| Abstract : |
| PubMedSearch : Tang_2023_J.Enzyme.Inhib.Med.Chem_38_2237213 |
| PubMedID: 37501629 |
| Title : Sulfur-fluoride exchange (SuFEx)-enabled lead discovery of AChE inhibitors by fragment linking strategies - Zhang_2023_Eur.J.Med.Chem_257_115502 |
| Author(s) : Zhang Z , Zhang SL , Wu C , Li HH , Zha L , Shi J , Liu X , Qin HL , Tang W |
| Ref : Eur Journal of Medicinal Chemistry , 257 :115502 , 2023 |
| Abstract : |
| PubMedSearch : Zhang_2023_Eur.J.Med.Chem_257_115502 |
| PubMedID: 37224761 |
| Title : Fluorosulfate-containing pyrazole heterocycles as selective BuChE inhibitors: structure-activity relationship and biological evaluation for the treatment of Alzheimer's disease - Li_2022_J.Enzyme.Inhib.Med.Chem_37_2099 |
| Author(s) : Li HH , Wu C , Zhang SL , Yang JG , Qin HL , Tang W |
| Ref : J Enzyme Inhib Med Chem , 37 :2099 , 2022 |
| Abstract : |
| PubMedSearch : Li_2022_J.Enzyme.Inhib.Med.Chem_37_2099 |
| PubMedID: 35899776 |
| Title : Novel pyridine-containing sultones: Structure-activity relationship and biological evaluation as selective AChE inhibitors for the treatment of Alzheimer's disease - Tang_2021_ChemMedChem__ |
| Author(s) : Tang W , Zhang H , Wu C , Chen X , Zhang Z , Jiang X , Qin HL |
| Ref : ChemMedChem , : , 2021 |
| Abstract : |
| PubMedSearch : Tang_2021_ChemMedChem__ |
| PubMedID: 34036731 |
| Title : Structure-activity relationship, in vitro and in vivo evaluation of novel dienyl sulphonyl fluorides as selective BuChE inhibitors for the treatment of Alzheimer's disease - Wu_2021_J.Enzyme.Inhib.Med.Chem_36_1860 |
| Author(s) : Wu C , Zhang G , Zhang ZW , Jiang X , Zhang Z , Li H , Qin HL , Tang W |
| Ref : J Enzyme Inhib Med Chem , 36 :1860 , 2021 |
| Abstract : |
| PubMedSearch : Wu_2021_J.Enzyme.Inhib.Med.Chem_36_1860 |
| PubMedID: 34425715 |
| Title : Discovery of delta-sultone-fused pyrazoles for treating Alzheimer's disease: Design, synthesis, biological evaluation and SAR studies - Xu_2019_Eur.J.Med.Chem_181_111598 |
| Author(s) : Xu Y , Zhang Z , Jiang X , Chen X , Wang Z , Alsulami H , Qin HL , Tang W |
| Ref : Eur Journal of Medicinal Chemistry , 181 :111598 , 2019 |
| Abstract : |
| PubMedSearch : Xu_2019_Eur.J.Med.Chem_181_111598 |
| PubMedID: 31415981 |
| Title : Synthesis and biological evaluation of new tetramethylpyrazine-based chalcone derivatives as potential anti-Alzheimer agents - Wang_2018_Chem.Biol.Drug.Des_92_1859 |
| Author(s) : Wang M , Qin HL , Leng J , Ameeduzzafar , Amjad MW , Raja MAG , Hussain MA , Bukhari SNA |
| Ref : Chemical Biology Drug Des , 92 :1859 , 2018 |
| Abstract : |
| PubMedSearch : Wang_2018_Chem.Biol.Drug.Des_92_1859 |
| PubMedID: 29923315 |
| Title : Multi-targetable chalcone analogs to treat deadly Alzheimer's disease: Current view and upcoming advice - Zhang_2018_Bioorg.Chem_80_86 |
| Author(s) : Zhang X , Rakesh KP , Bukhari SNA , Balakrishna M , Manukumar HM , Qin HL |
| Ref : Bioorg Chem , 80 :86 , 2018 |
| Abstract : |
| PubMedSearch : Zhang_2018_Bioorg.Chem_80_86 |
| PubMedID: 29890362 |
| Title : Biological evaluation of synthetic alpha,beta-unsaturated carbonyl based cyclohexanone derivatives as neuroprotective novel inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-beta aggregation - Zha_2016_Bioorg.Med.Chem_24_2352 |
| Author(s) : Zha GF , Zhang CP , Qin HL , Jantan I , Sher M , Amjad MW , Hussain MA , Hussain Z , Bukhari SN |
| Ref : Bioorganic & Medicinal Chemistry , 24 :2352 , 2016 |
| Abstract : |
| PubMedSearch : Zha_2016_Bioorg.Med.Chem_24_2352 |
| PubMedID: 27083471 |
| Title : Evaluation of multifunctional synthetic tetralone derivatives for treatment of Alzheimer's disease - Leng_2016_Chem.Biol.Drug.Des_88_889 |
| Author(s) : Leng J , Qin HL , Zhu K , Jantan I , Hussain MA , Sher M , Amjad MW , Naeem-Ul-Hassan M , Ahmad W , Bukhari SN |
| Ref : Chemical Biology Drug Des , 88 :889 , 2016 |
| Abstract : |
| PubMedSearch : Leng_2016_Chem.Biol.Drug.Des_88_889 |
| PubMedID: 27434226 |
| Title : Novel alkaloids from the roots of Stemona sessilifolia - Wang_2007_Chem.Biodivers_4_523 |
| Author(s) : Wang P , Liu AL , An Z , Li ZH , Du GH , Qin HL |
| Ref : Chem Biodivers , 4 :523 , 2007 |
| Abstract : |
| PubMedSearch : Wang_2007_Chem.Biodivers_4_523 |
| PubMedID: 17372955 |