| Title : Substituted piperidinyl glycinyl 2-cyano-4,5-methano pyrrolidines as potent and stable dipeptidyl peptidase IV inhibitors - Zhao_2013_Bioorg.Med.Chem.Lett_23_1622 |
| Author(s) : Zhao G , Kwon C , Wang A , Robertson JG , Marcinkeviciene J , Parker RA , Kirby MS , Hamann LG |
| Ref : Bioorganic & Medicinal Chemistry Lett , 23 :1622 , 2013 |
| Abstract : |
| PubMedSearch : Zhao_2013_Bioorg.Med.Chem.Lett_23_1622 |
| PubMedID: 23416006 |
| Title : Potent non-nitrile dipeptidic dipeptidyl peptidase IV inhibitors - Simpkins_2007_Bioorg.Med.Chem.Lett_17_6476 |
| Author(s) : Simpkins LM , Bolton S , Pi Z , Sutton JC , Kwon C , Zhao G , Magnin DR , Augeri DJ , Gungor T , Rotella DP , Sun Z , Liu Y , Slusarchyk WS , Marcinkeviciene J , Robertson JG , Wang A , Robl JA , Atwal KS , Zahler RL , Parker RA , Kirby MS , Hamann LG |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :6476 , 2007 |
| Abstract : |
| PubMedSearch : Simpkins_2007_Bioorg.Med.Chem.Lett_17_6476 |
| PubMedID: 17937986 |
| Title : Enzymes as a special class of therapeutic target: clinical drugs and modes of action - Robertson_2007_Curr.Opin.Struct.Biol_17_674 |
| Author(s) : Robertson JG |
| Ref : Current Opinion in Structural Biology , 17 :674 , 2007 |
| Abstract : |
| PubMedSearch : Robertson_2007_Curr.Opin.Struct.Biol_17_674 |
| PubMedID: 17884461 |
| Title : Seco-prolinenitrile inhibitors of dipeptidyl peptidase IV define minimal pharmacophore requirements at P1 - Magnin_2006_Bioorg.Med.Chem.Lett_16_1731 |
| Author(s) : Magnin DR , Taunk PC , Robertson JG , Wang A , Marcinkeviciene J , Kirby MS , Hamann LG |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :1731 , 2006 |
| Abstract : |
| PubMedSearch : Magnin_2006_Bioorg.Med.Chem.Lett_16_1731 |
| PubMedID: 16376077 |
| Title : Diprolyl nitriles as potent dipeptidyl peptidase IV inhibitors - Zhao_2005_Bioorg.Med.Chem.Lett_15_3992 |
| Author(s) : Zhao G , Taunk PC , Magnin DR , Simpkins LM , Robl JA , Wang A , Robertson JG , Marcinkeviciene J , Sitkoff DF , Parker RA , Kirby MS , Hamann LG |
| Ref : Bioorganic & Medicinal Chemistry Lett , 15 :3992 , 2005 |
| Abstract : |
| PubMedSearch : Zhao_2005_Bioorg.Med.Chem.Lett_15_3992 |
| PubMedID: 16046120 |
| Title : Discovery and preclinical profile of Saxagliptin (BMS-477118): a highly potent, long-acting, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes - Augeri_2005_J.Med.Chem_48_5025 |
| Author(s) : Augeri DJ , Robl JA , Betebenner DA , Magnin DR , Khanna A , Robertson JG , Wang A , Simpkins LM , Taunk P , Huang Q , Han SP , Abboa-Offei B , Cap M , Xin L , Tao L , Tozzo E , Welzel GE , Egan DM , Marcinkeviciene J , Chang SY , Biller SA , Kirby MS , Parker RA , Hamann LG |
| Ref : Journal of Medicinal Chemistry , 48 :5025 , 2005 |
| Abstract : |
| PubMedSearch : Augeri_2005_J.Med.Chem_48_5025 |
| PubMedID: 16033281 |
| Title : Synthesis of novel potent dipeptidyl peptidase IV inhibitors with enhanced chemical stability: interplay between the N-terminal amino acid alkyl side chain and the cyclopropyl group of alpha-aminoacyl-l-cis-4,5-methanoprolinenitrile-based inhibitors - Magnin_2004_J.Med.Chem_47_2587 |
| Author(s) : Magnin DR , Robl JA , Sulsky RB , Augeri DJ , Huang Y , Simpkins LM , Taunk PC , Betebenner DA , Robertson JG , Abboa-Offei BE , Wang A , Cap M , Xin L , Tao L , Sitkoff DF , Malley MF , Gougoutas JZ , Khanna A , Huang Q , Han SP , Parker RA , Hamann LG |
| Ref : Journal of Medicinal Chemistry , 47 :2587 , 2004 |
| Abstract : |
| PubMedSearch : Magnin_2004_J.Med.Chem_47_2587 |
| PubMedID: 15115400 |
| Title : Maturation of human skeletal muscle fibres in explant tissue culture - Harvey_1979_J.Neurol.Sci_41_115 |
| Author(s) : Harvey AL , Robertson JG , Witkowski JA |
| Ref : Journal of Neurology Sci , 41 :115 , 1979 |
| Abstract : |
| PubMedSearch : Harvey_1979_J.Neurol.Sci_41_115 |
| PubMedID: 438841 |
| Title : Development of transient myasthenia-like symptoms in chickens injected with acetylcholine receptor from Torpedo marmorata [proceedings] - |
| Author(s) : Barkas T , Harrison R , Lunt GG , Watson CM , Harvey AL , Robertson JG |
| Ref : Biochemical Society Transactions , 6 :634 , 1978 |
| PubMedID: 669035 |
| Title : Reduction of acetylcholine sensitivity of chick muscle in culture by myasthenia gravis serum - |
| Author(s) : Harvey AL , Robertson JG , Barkas T , Harrison R , Lunt GG , Stephenson FA , Campbell MJ , Teague RH |
| Ref : Clinical & Experimental Immunology , 34 :411 , 1978 |
| PubMedID: 743809 |