Rocke BN

Title : Insights into the Novel Hydrolytic Mechanism of a Diethyl 2-Phenyl-2-(2-arylacetoxy)methyl Malonate Ester-Based Microsomal Triglyceride Transfer Protein (MTP) Inhibitor - Ryder_2012_Chem.Res.Toxicol_25_2138

Author(s) : Ryder T , Walker GS , Goosen TC , Ruggeri RB , Conn EL , Rocke BN , Lapham K , Steppan CM , Hepworth D , Kalgutkar AS

Ref : Chemical Research in Toxicology , 25 :2138 , 2012

Abstract :

PubMedSearch : Ryder_2012_Chem.Res.Toxicol_25_2138

PubMedID: 22989032

Title : (3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: synthesis, in vitro, in vivo, and X-ray crystallographic characterization - Wright_2007_Bioorg.Med.Chem.Lett_17_5638

Author(s) : Wright SW , Ammirati MJ , Andrews KM , Brodeur AM , Danley DE , Doran SD , Lillquist JS , Liu S , McClure LD , McPherson RK , Olson TV , Orena SJ , Parker JC , Rocke BN , Soeller WC , Soglia CB , Treadway JL , VanVolkenburg MA , Zhao Z , Cox ED

Ref : Bioorganic & Medicinal Chemistry Lett , 17 :5638 , 2007

Abstract :

PubMedSearch : Wright_2007_Bioorg.Med.Chem.Lett_17_5638

PubMedID: 17822893

Gene_locus related to this paper: human-DPP4

Rocke BN

References (2)

1. Insights into the Novel Hydrolytic Mechanism of a Diethyl 2-Phenyl-2-(2-arylacetoxy)methyl Malonate Ester-Based Microsomal Triglyceride Transfer Protein (MTP) Inhibitor - Ryder_2012_Chem.Res.Toxicol_25_2138

2. (3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: synthesis, in vitro, in vivo, and X-ray crystallographic characterization - Wright_2007_Bioorg.Med.Chem.Lett_17_5638