Title : Poster: Low efficacy partial agonists of the alpha4\/beta2 nicotinic acetylcholine receptor (nAChR). Does functional efficacy govern in vivo response? - |
Author(s) : Coe JW , Brooks PR , Wirtz MC , Vetelino MG , Arnold EP , Sands SB , Davis TI , Lebel LA , Fox CB , Shrikhande A , Mansbach RS , Chambers LK , Rovetti CC , Schulz DW , Tingley Iii FD , ONeill BT , Rollema H |
Ref : Biochemical Pharmacology , 78 :919 , 2009 |
PubMedID: |
Title : Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid - Rollema_2007_Neuropharmacol_52_985 |
Author(s) : Rollema H , Chambers LK , Coe JW , Glowa J , Hurst RS , Lebel LA , Lu Y , Mansbach RS , Mather RJ , Rovetti CC , Sands SB , Schaeffer E , Schulz DW , Tingley FD, 3rd , Williams KE |
Ref : Neuropharmacology , 52 :985 , 2007 |
Abstract : |
PubMedSearch : Rollema_2007_Neuropharmacol_52_985 |
PubMedID: 17157884 |
Title : Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation - Coe_2005_J.Med.Chem_48_3474 |
Author(s) : Coe JW , Brooks PR , Vetelino MG , Wirtz MC , Arnold EP , Huang J , Sands SB , Davis TI , Lebel LA , Fox CB , Shrikhande A , Heym JH , Schaeffer E , Rollema H , Lu Y , Mansbach RS , Chambers LK , Rovetti CC , Schulz DW , Tingley FD, 3rd , O'Neill BT |
Ref : Journal of Medicinal Chemistry , 48 :3474 , 2005 |
Abstract : |
PubMedSearch : Coe_2005_J.Med.Chem_48_3474 |
PubMedID: 15887955 |
Title : 3,5-Bicyclic aryl piperidines: a novel class of alpha4beta2 neuronal nicotinic receptor partial agonists for smoking cessation - Coe_2005_Bioorg.Med.Chem.Lett_15_4889 |
Author(s) : Coe JW , Brooks PR , Wirtz MC , Bashore CG , Bianco KE , Vetelino MG , Arnold EP , Lebel LA , Fox CB , Tingley FD, 3rd , Schulz DW , Davis TI , Sands SB , Mansbach RS , Rollema H , O'Neill BT |
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :4889 , 2005 |
Abstract : |
PubMedSearch : Coe_2005_Bioorg.Med.Chem.Lett_15_4889 |
PubMedID: 16171993 |
Title : In pursuit of alpha4beta2 nicotinic receptor partial agonists for smoking cessation: carbon analogs of (-)-cytisine - Coe_2005_Bioorg.Med.Chem.Lett_15_2974 |
Author(s) : Coe JW , Vetelino MG , Bashore CG , Wirtz MC , Brooks PR , Arnold EP , Lebel LA , Fox CB , Sands SB , Davis TI , Schulz DW , Rollema H , Tingley FD, 3rd , O'Neill BT |
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :2974 , 2005 |
Abstract : |
PubMedSearch : Coe_2005_Bioorg.Med.Chem.Lett_15_2974 |
PubMedID: 15908213 |
Title : Autoradiographic localization of putative nicotinic receptors in the rat brain using 125I-neuronal bungarotoxin - Schulz_1991_J.Neurosci_11_287 |
Author(s) : Schulz DW , Loring RH , Aizenman E , Zigmond RE |
Ref : Journal of Neuroscience , 11 :287 , 1991 |
Abstract : |
PubMedSearch : Schulz_1991_J.Neurosci_11_287 |
PubMedID: 1986068 |
Title : Characterization of neuronal nicotinic receptors using neuronal bungarotoxin - |
Author(s) : Loring RH , Schulz DW , Zigmond RE |
Ref : Prog Brain Res , 79 :109 , 1989 |
PubMedID: 2685893 |