Rollema H

General

Full name : Rollema Hans

First name : Hans

Mail : Rollema Biomedical Consulting, Mystic, 06355 CT

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City :

Country : USA

Email : hans.rollema@gmail.com

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References (25)

Title : Functional interactions of varenicline and nicotine with nAChR subtypes implicated in cardiovascular control - Rollema_2014_Nicotine.Tob.Res_16_733
Author(s) : Rollema H , Russ C , Lee TC , Hurst RS , Bertrand D
Ref : Nicotine Tob Res , 16 :733 , 2014
Abstract :
PubMedSearch : Rollema_2014_Nicotine.Tob.Res_16_733
PubMedID: 24406270

Title : Therapeutic doses of antidepressants are projected not to inhibit human alpha4beta2 nicotinic acetylcholine receptors - Weber_2013_Neuropharmacol_72_88
Author(s) : Weber ML , Hofland CM , Shaffer CL , Flik G , Cremers T , Hurst RS , Rollema H
Ref : Neuropharmacology , 72 :88 , 2013
Abstract :
PubMedSearch : Weber_2013_Neuropharmacol_72_88
PubMedID: 23639435

Title : Nicotinic acetylcholine receptors: from basic science to therapeutics - Hurst_2013_Pharmacol.Ther_137_22
Author(s) : Hurst RS , Rollema H , Bertrand D
Ref : Pharmacol Ther , 137 :22 , 2013
Abstract :
PubMedSearch : Hurst_2013_Pharmacol.Ther_137_22
PubMedID: 22925690

Title : Direct effect of nicotine on mesolimbic dopamine release in rat nucleus accumbens shell - Kleijn_2011_Neurosci.Lett_493_55
Author(s) : Kleijn J , Folgering JH , van der Hart MC , Rollema H , Cremers TI , Westerink BH
Ref : Neuroscience Letters , 493 :55 , 2011
Abstract :
PubMedSearch : Kleijn_2011_Neurosci.Lett_493_55
PubMedID: 21352892

Title : Effect of co-administration of varenicline and antidepressants on extracellular monoamine concentrations in rat prefrontal cortex - Rollema_2011_Neurochem.Int_58_78
Author(s) : Rollema H , Wilson GG , Lee TC , Folgering JH , Flik G
Ref : Neurochem Int , 58 :78 , 2011
Abstract :
PubMedSearch : Rollema_2011_Neurochem.Int_58_78
PubMedID: 21056607

Title : alpha4beta2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties - Mineur_2011_Behav.Pharmacol_22_291
Author(s) : Mineur YS , Einstein EB , Seymour PA , Coe JW , O'Neill B T , Rollema H , Picciotto MR
Ref : Behav Pharmacol , 22 :291 , 2011
Abstract :
PubMedSearch : Mineur_2011_Behav.Pharmacol_22_291
PubMedID: 21566524

Title : Partial agonists of the alpha3beta4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats - Chatterjee_2011_Neuropsychopharmacology_36_603
Author(s) : Chatterjee S , Steensland P , Simms JA , Holgate J , Coe JW , Hurst RS , Shaffer CL , Lowe J , Rollema H , Bartlett SE
Ref : Neuropsychopharmacology , 36 :603 , 2011
Abstract :
PubMedSearch : Chatterjee_2011_Neuropsychopharmacology_36_603
PubMedID: 21048701

Title : A review of the clinical pharmacokinetics and pharmacodynamics of varenicline for smoking cessation - Faessel_2010_Clin.Pharmacokinet_49_799
Author(s) : Faessel HM , Obach RS , Rollema H , Ravva P , Williams KE , Burstein AH
Ref : Clinical Pharmacokinetics , 49 :799 , 2010
Abstract :
PubMedSearch : Faessel_2010_Clin.Pharmacokinet_49_799
PubMedID: 21053991

Title : A novel series of [3.2.1] azabicyclic biaryl ethers as alpha3beta4 and alpha6\/4beta4 nicotinic receptor agonists - Lowe_2010_Bioorg.Med.Chem.Lett_20_4749
Author(s) : Lowe JA, 3rd , DeNinno SL , Coe JW , Zhang L , Mente S , Hurst RS , Mather RJ , Ward KM , Shrikhande A , Rollema H , Johnson DE , Horner W , Gorczyca R , Tingley FD, 3rd , Kozak R , Majchrzak MJ , Tritto T , Sadlier J , Shaffer CL , Ellerbrock B , Osgood SM , MacDougall MC , McDowell LL
Ref : Bioorganic & Medicinal Chemistry Lett , 20 :4749 , 2010
Abstract :
PubMedSearch : Lowe_2010_Bioorg.Med.Chem.Lett_20_4749
PubMedID: 20663668

Title : Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence - Rollema_2010_Br.J.Pharmacol_160_334
Author(s) : Rollema H , Shrikhande A , Ward KM , Tingley FD, 3rd , Coe JW , O'Neill BT , Tseng E , Wang EQ , Mather RJ , Hurst RS , Williams KE , De Vries M , Cremers T , Bertrand S , Bertrand D
Ref : British Journal of Pharmacology , 160 :334 , 2010
Abstract :
PubMedSearch : Rollema_2010_Br.J.Pharmacol_160_334
PubMedID: 20331614

Title : Effect of the alpha4beta2* nicotinic acetylcholine receptor partial agonist varenicline on dopamine release in beta2 knock-out mice with selective re-expression of the beta2 subunit in the ventral tegmental area - Reperant_2010_Neuropharmacol_58_346
Author(s) : Reperant C , Pons S , Dufour E , Rollema H , Gardier AM , Maskos U
Ref : Neuropharmacology , 58 :346 , 2010
Abstract :
PubMedSearch : Reperant_2010_Neuropharmacol_58_346
PubMedID: 19887076

Title : The alpha4beta2 nicotinic acetylcholine-receptor partial agonist varenicline inhibits both nicotine self-administration following repeated dosing and reinstatement of nicotine seeking in rats - O'Connor_2010_Psychopharmacology.(Berl)_208_365
Author(s) : O'Connor EC , Parker D , Rollema H , Mead AN
Ref : Psychopharmacology (Berl) , 208 :365 , 2010
Abstract :
PubMedSearch : O'Connor_2010_Psychopharmacology.(Berl)_208_365
PubMedID: 19967529

Title : Varenicline in smoking cessation - Tonstad_2010_Expert.Rev.Respir.Med_4_291
Author(s) : Tonstad S , Rollema H
Ref : Expert Rev Respir Med , 4 :291 , 2010
Abstract :
PubMedSearch : Tonstad_2010_Expert.Rev.Respir.Med_4_291
PubMedID: 20524911

Title : Poster: Preclinical properties of the alpha4\/beta2 nAChR partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence -
Author(s) : Rollema H , Shrikhande A , Ward KM , Coe JW , Tseng E , Wang EQ , De Vries M , Cremers THIF , Bertrand S , Bertrand D
Ref : Biochemical Pharmacology , 78 :918 , 2009
PubMedID:

Title : Varenicline overdose in a teenager--a clinical pharmacology perspective -
Author(s) : Rollema H , Faessel HM , Williams KE
Ref : Clinical Toxicology (Phila) , 47 :605 , 2009
PubMedID: 19586362

Title : Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect - Rollema_2009_Eur.J.Pharmacol_605_114
Author(s) : Rollema H , Guanowsky V , Mineur YS , Shrikhande A , Coe JW , Seymour PA , Picciotto MR
Ref : European Journal of Pharmacology , 605 :114 , 2009
Abstract :
PubMedSearch : Rollema_2009_Eur.J.Pharmacol_605_114
PubMedID: 19168054

Title : Poster: Low efficacy partial agonists of the alpha4\/beta2 nicotinic acetylcholine receptor (nAChR). Does functional efficacy govern in vivo response? -
Author(s) : Coe JW , Brooks PR , Wirtz MC , Vetelino MG , Arnold EP , Sands SB , Davis TI , Lebel LA , Fox CB , Shrikhande A , Mansbach RS , Chambers LK , Rovetti CC , Schulz DW , Tingley Iii FD , ONeill BT , Rollema H
Ref : Biochemical Pharmacology , 78 :919 , 2009
PubMedID:

Title : Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition - Rollema_2009_Biochem.Pharmacol_78(7)_813
Author(s) : Rollema H , Hajos M , Seymour PA , Kozak R , Majchrzak MJ , Guanowsky V , Horner WE , Chapin DS , Hoffmann WE , Johnson DE , McLean S , Freeman J , Williams KE
Ref : Biochemical Pharmacology , 78 :813 , 2009
Abstract :
PubMedSearch : Rollema_2009_Biochem.Pharmacol_78(7)_813
PubMedID: 19501054

Title : Varenicline: new treatment with efficacy in smoking cessation - Reus_2007_Drugs.Today.(Barc)_43_65
Author(s) : Reus VI , Obach RS , Coe JW , Faessel H , Rollema H , Watsky E , Reeves K
Ref : Drugs Today (Barc) , 43 :65 , 2007
Abstract :
PubMedSearch : Reus_2007_Drugs.Today.(Barc)_43_65
PubMedID: 17353944

Title : Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid - Rollema_2007_Neuropharmacol_52_985
Author(s) : Rollema H , Chambers LK , Coe JW , Glowa J , Hurst RS , Lebel LA , Lu Y , Mansbach RS , Mather RJ , Rovetti CC , Sands SB , Schaeffer E , Schulz DW , Tingley FD, 3rd , Williams KE
Ref : Neuropharmacology , 52 :985 , 2007
Abstract :
PubMedSearch : Rollema_2007_Neuropharmacol_52_985
PubMedID: 17157884

Title : Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation - Rollema_2007_Trends.Pharmacol.Sci_28_316
Author(s) : Rollema H , Coe JW , Chambers LK , Hurst RS , Stahl SM , Williams KE
Ref : Trends in Pharmacological Sciences , 28 :316 , 2007
Abstract :
PubMedSearch : Rollema_2007_Trends.Pharmacol.Sci_28_316
PubMedID: 17573127

Title : The role of muscarinic receptor antagonism in antipsychotic-induced hippocampal acetylcholine release - Johnson_2005_Eur.J.Pharmacol_506_209
Author(s) : Johnson DE , Nedza FM , Spracklin DK , Ward KM , Schmidt AW , Iredale PA , Godek DM , Rollema H
Ref : European Journal of Pharmacology , 506 :209 , 2005
Abstract :
PubMedSearch : Johnson_2005_Eur.J.Pharmacol_506_209
PubMedID: 15627430

Title : Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation - Coe_2005_J.Med.Chem_48_3474
Author(s) : Coe JW , Brooks PR , Vetelino MG , Wirtz MC , Arnold EP , Huang J , Sands SB , Davis TI , Lebel LA , Fox CB , Shrikhande A , Heym JH , Schaeffer E , Rollema H , Lu Y , Mansbach RS , Chambers LK , Rovetti CC , Schulz DW , Tingley FD, 3rd , O'Neill BT
Ref : Journal of Medicinal Chemistry , 48 :3474 , 2005
Abstract :
PubMedSearch : Coe_2005_J.Med.Chem_48_3474
PubMedID: 15887955

Title : 3,5-Bicyclic aryl piperidines: a novel class of alpha4beta2 neuronal nicotinic receptor partial agonists for smoking cessation - Coe_2005_Bioorg.Med.Chem.Lett_15_4889
Author(s) : Coe JW , Brooks PR , Wirtz MC , Bashore CG , Bianco KE , Vetelino MG , Arnold EP , Lebel LA , Fox CB , Tingley FD, 3rd , Schulz DW , Davis TI , Sands SB , Mansbach RS , Rollema H , O'Neill BT
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :4889 , 2005
Abstract :
PubMedSearch : Coe_2005_Bioorg.Med.Chem.Lett_15_4889
PubMedID: 16171993

Title : In pursuit of alpha4beta2 nicotinic receptor partial agonists for smoking cessation: carbon analogs of (-)-cytisine - Coe_2005_Bioorg.Med.Chem.Lett_15_2974
Author(s) : Coe JW , Vetelino MG , Bashore CG , Wirtz MC , Brooks PR , Arnold EP , Lebel LA , Fox CB , Sands SB , Davis TI , Schulz DW , Rollema H , Tingley FD, 3rd , O'Neill BT
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :2974 , 2005
Abstract :
PubMedSearch : Coe_2005_Bioorg.Med.Chem.Lett_15_2974
PubMedID: 15908213