Spagnuolo R

Title : One destination, three routes: Tacrine-Celecoxib hybrids targeting cholinesterases, COX-2, and carbonic anhydrases in cognitive impairment linked to metabolic dysfunction - Hassan_2026_Eur.J.Med.Chem_315_118984

Author(s) : Hassan NW , Afifi OS , El-Attar MAZ , Kamel YN , Yassin HA , Nomeir HM , Angeli A , Labib HF , Elsheikh MA , Zewail M , Gerges EM , El-Yazbi AF , Spagnuolo R , Naldi M , Ashmawy MI , Zahra WK , Hammad SF , Supuran CT , Bartolini M , Elzahhar PA , Belal ASF , Abd El Wahab SM

Ref : Eur Journal of Medicinal Chemistry , 315 :118984 , 2026

Abstract :

PubMedSearch : Hassan_2026_Eur.J.Med.Chem_315_118984

PubMedID: 42190432

Title : Synthesis and Biological Profiling of New 1,2,3,4-Tetrahydrobenzo[h]naphthyridine-Based Hybrids as Dual Inhibitors of beta-Amyloid and Tau Aggregation with Anticholinesterase Activity - Verano_2026_Biomolecules_16_593

Author(s) : Verano AB , Sampietro A , Mallo-Abreu A , Spagnuolo R , Perez B , Bartolini M , Loza MI , Brea J , Juarez-Jimenez J , Sabate R , Galdeano C , Munoz-Torrero D

Ref : Biomolecules , 16 : , 2026

Abstract :

PubMedSearch : Verano_2026_Biomolecules_16_593

PubMedID: 42072714

Spagnuolo R

References (2)

1. One destination, three routes: Tacrine-Celecoxib hybrids targeting cholinesterases, COX-2, and carbonic anhydrases in cognitive impairment linked to metabolic dysfunction - Hassan_2026_Eur.J.Med.Chem_315_118984

2. Synthesis and Biological Profiling of New 1,2,3,4-Tetrahydrobenzo[h]naphthyridine-Based Hybrids as Dual Inhibitors of beta-Amyloid and Tau Aggregation with Anticholinesterase Activity - Verano_2026_Biomolecules_16_593