Ulens C

General

Full name : Ulens Chris

First name : Chris

Mail : Laboratory of Structural Neurobiology, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, PB 601, B-3000 Leuven

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Country : Belgium

Email : chris.ulens@med.kuleuven.be

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References (12)

Title : Structural hot spots for the solubility of globular proteins - Ganesan_2016_Nat.Commun_7_10816
Author(s) : Ganesan A , Siekierska A , Beerten J , Brams M , Van Durme J , De Baets G , Van der Kant R , Gallardo R , Ramakers M , Langenberg T , Wilkinson H , De Smet F , Ulens C , Rousseau F , Schymkowitz J
Ref : Nat Commun , 7 :10816 , 2016
Abstract :
PubMedSearch : Ganesan_2016_Nat.Commun_7_10816
PubMedID: 26905391

Title : Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues - Wijckmans_2016_PLoS.One_11_e0151183
Author(s) : Wijckmans E , Nys M , Debaveye S , Brams M , Pardon E , Willegems K , Bertrand D , Steyaert J , Efremov R , Ulens C
Ref : PLoS ONE , 11 :e0151183 , 2016
Abstract :
PubMedSearch : Wijckmans_2016_PLoS.One_11_e0151183
PubMedID: 26999666

Title : Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the alpha7 nicotinic acetylcholine receptor - Spurny_2015_Proc.Natl.Acad.Sci.U.S.A_112_E2543
Author(s) : Spurny R , Debaveye S , Farinha A , Veys K , Vos AM , Gossas T , Atack J , Bertrand S , Bertrand D , Danielson UH , Tresadern G , Ulens C
Ref : Proc Natl Acad Sci U S A , 112 :E2543 , 2015
Abstract :
PubMedSearch : Spurny_2015_Proc.Natl.Acad.Sci.U.S.A_112_E2543
PubMedID: 25918415

Title : The prokaryote ligand-gated ion channel ELIC captured in a pore blocker-bound conformation by the Alzheimer's disease drug memantine - Ulens_2014_Structure_22_1399
Author(s) : Ulens C , Spurny R , Thompson AJ , Alqazzaz M , Debaveye S , Han L , Price K , Villalgordo JM , Tresadern G , Lynch JW , Lummis SC
Ref : Structure , 22 :1399 , 2014
Abstract :
PubMedSearch : Ulens_2014_Structure_22_1399
PubMedID: 25199693

Title : Structural insights into Cys-loop receptor function and ligand recognition - Nys_2013_Biochem.Pharmacol_86(8)_1042
Author(s) : Nys M , Kesters D , Ulens C
Ref : Biochemical Pharmacology , 86 :1042 , 2013
Abstract :
PubMedSearch : Nys_2013_Biochem.Pharmacol_86(8)_1042
PubMedID: 23850718

Title : The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor - Thompson_2012_Neuropharmacol_63_761
Author(s) : Thompson AJ , Alqazzaz M , Ulens C , Lummis SC
Ref : Neuropharmacology , 63 :761 , 2012
Abstract :
PubMedSearch : Thompson_2012_Neuropharmacol_63_761
PubMedID: 22677470

Title : Molecular actions of smoking cessation drugs at alpha4beta2 nicotinic receptors defined in crystal structures of a homologous binding protein - Billen_2012_Proc.Natl.Acad.Sci.U.S.A_109_9173
Author(s) : Billen B , Spurny R , Brams M , van Elk R , Valera-Kummer S , Yakel JL , Voets T , Bertrand D , Smit AB , Ulens C
Ref : Proc Natl Acad Sci U S A , 109 :9173 , 2012
Abstract :
PubMedSearch : Billen_2012_Proc.Natl.Acad.Sci.U.S.A_109_9173
PubMedID: 22619328

Title : Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein - Brams_2011_J.Biol.Chem_286_4420
Author(s) : Brams M , Gay EA , Saez JC , Guskov A , van Elk R , van der Schors RC , Peigneur S , Tytgat J , Strelkov SV , Smit AB , Yakel JL , Ulens C
Ref : Journal of Biological Chemistry , 286 :4420 , 2011
Abstract :
PubMedSearch : Brams_2011_J.Biol.Chem_286_4420
PubMedID: 21115477

Title : A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors - Brams_2011_PLoS.Biol_9_e1001034
Author(s) : Brams M , Pandya A , Kuzmin D , van Elk R , Krijnen L , Yakel JL , Tsetlin V , Smit AB , Ulens C
Ref : PLoS Biol , 9 :e1001034 , 2011
Abstract :
PubMedSearch : Brams_2011_PLoS.Biol_9_e1001034
PubMedID: 21468359

Title : Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis - Ulens_2009_J.Med.Chem_52_2372
Author(s) : Ulens C , Akdemir A , Jongejan A , van Elk R , Bertrand S , Perrakis A , Leurs R , Smit AB , Sixma TK , Bertrand D , de Esch IJ
Ref : Journal of Medicinal Chemistry , 52 :2372 , 2009
Abstract :
PubMedSearch : Ulens_2009_J.Med.Chem_52_2372
PubMedID: 19331415

Title : AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity - Dutertre_2007_EMBO.J_26_3858
Author(s) : Dutertre S , Ulens C , Buttner R , Fish A , van Elk R , Kendel Y , Hopping G , Alewood PF , Schroeder C , Nicke A , Smit AB , Sixma TK , Lewis RJ
Ref : EMBO Journal , 26 :3858 , 2007
Abstract :
PubMedSearch : Dutertre_2007_EMBO.J_26_3858
PubMedID: 17660751

Title : Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP - Ulens_2006_Proc.Natl.Acad.Sci.U.S.A_103_3615
Author(s) : Ulens C , Hogg RC , Celie PH , Bertrand D , Tsetlin V , Smit AB , Sixma TK
Ref : Proc Natl Acad Sci U S A , 103 :3615 , 2006
Abstract :
PubMedSearch : Ulens_2006_Proc.Natl.Acad.Sci.U.S.A_103_3615
PubMedID: 16505382