Full name : Lummis Sarah C
First name : Sarah C
Mail : Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW
Zip Code :
City :
Country : United Kingdom
Email : sI120@cam.ac.uk
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Website :
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Comment
| Title : The nicotinic alpha6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2\/3 receptors - Wieskopf_2015_Sci.Transl.Med_7_287ra72 |
| Author(s) : Wieskopf JS , Mathur J , Limapichat W , Post MR , Al-Qazzaz M , Sorge RE , Martin LJ , Zaykin DV , Smith SB , Freitas K , Austin JS , Dai F , Zhang J , Marcovitz J , Tuttle AH , Slepian PM , Clarke S , Drenan RM , Janes J , Al Sharari S , Segall SK , Aasvang EK , Lai W , Bittner R , Richards CI , Slade GD , Kehlet H , Walker J , Maskos U , Changeux JP , Devor M , Maixner W , Diatchenko L , Belfer I , Dougherty DA , Su AI , Lummis SC , Damaj MI , Lester HA , Patapoutian A , Mogil JS |
| Ref : Sci Transl Med , 7 :287ra72 , 2015 |
| Abstract : |
| PubMedSearch : Wieskopf_2015_Sci.Transl.Med_7_287ra72 |
| PubMedID: 25972004 |
| Title : The nicotinic alpha6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2\/3 receptors - Wieskopf_2015_Sci.Transl.Med_7_287ra72 |
| Author(s) : Wieskopf JS , Mathur J , Limapichat W , Post MR , Al-Qazzaz M , Sorge RE , Martin LJ , Zaykin DV , Smith SB , Freitas K , Austin JS , Dai F , Zhang J , Marcovitz J , Tuttle AH , Slepian PM , Clarke S , Drenan RM , Janes J , Al Sharari S , Segall SK , Aasvang EK , Lai W , Bittner R , Richards CI , Slade GD , Kehlet H , Walker J , Maskos U , Changeux JP , Devor M , Maixner W , Diatchenko L , Belfer I , Dougherty DA , Su AI , Lummis SC , Damaj MI , Lester HA , Patapoutian A , Mogil JS |
| Ref : Sci Transl Med , 7 :287ra72 , 2015 |
| Abstract : |
| PubMedSearch : Wieskopf_2015_Sci.Transl.Med_7_287ra72 |
| PubMedID: 25972004 |
| Title : The prokaryote ligand-gated ion channel ELIC captured in a pore blocker-bound conformation by the Alzheimer's disease drug memantine - Ulens_2014_Structure_22_1399 |
| Author(s) : Ulens C , Spurny R , Thompson AJ , Alqazzaz M , Debaveye S , Han L , Price K , Villalgordo JM , Tresadern G , Lynch JW , Lummis SC |
| Ref : Structure , 22 :1399 , 2014 |
| Abstract : |
| PubMedSearch : Ulens_2014_Structure_22_1399 |
| PubMedID: 25199693 |
| Title : The prokaryote ligand-gated ion channel ELIC captured in a pore blocker-bound conformation by the Alzheimer's disease drug memantine - Ulens_2014_Structure_22_1399 |
| Author(s) : Ulens C , Spurny R , Thompson AJ , Alqazzaz M , Debaveye S , Han L , Price K , Villalgordo JM , Tresadern G , Lynch JW , Lummis SC |
| Ref : Structure , 22 :1399 , 2014 |
| Abstract : |
| PubMedSearch : Ulens_2014_Structure_22_1399 |
| PubMedID: 25199693 |
| Title : The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor - Thompson_2012_Neuropharmacol_63_761 |
| Author(s) : Thompson AJ , Alqazzaz M , Ulens C , Lummis SC |
| Ref : Neuropharmacology , 63 :761 , 2012 |
| Abstract : |
| PubMedSearch : Thompson_2012_Neuropharmacol_63_761 |
| PubMedID: 22677470 |
| Title : Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor - Utkin_2012_J.Biol.Chem_287_27079 |
| Author(s) : Utkin YN , Weise C , Kasheverov IE , Andreeva TV , Kryukova EV , Zhmak MN , Starkov VG , Hoang NA , Bertrand D , Ramerstorfer J , Sieghart W , Thompson AJ , Lummis SC , Tsetlin VI |
| Ref : Journal of Biological Chemistry , 287 :27079 , 2012 |
| Abstract : |
| PubMedSearch : Utkin_2012_J.Biol.Chem_287_27079 |
| PubMedID: 22613724 |
| Title : The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor - Thompson_2012_Neuropharmacol_63_761 |
| Author(s) : Thompson AJ , Alqazzaz M , Ulens C , Lummis SC |
| Ref : Neuropharmacology , 63 :761 , 2012 |
| Abstract : |
| PubMedSearch : Thompson_2012_Neuropharmacol_63_761 |
| PubMedID: 22677470 |
| Title : Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor - Utkin_2012_J.Biol.Chem_287_27079 |
| Author(s) : Utkin YN , Weise C , Kasheverov IE , Andreeva TV , Kryukova EV , Zhmak MN , Starkov VG , Hoang NA , Bertrand D , Ramerstorfer J , Sieghart W , Thompson AJ , Lummis SC , Tsetlin VI |
| Ref : Journal of Biological Chemistry , 287 :27079 , 2012 |
| Abstract : |
| PubMedSearch : Utkin_2012_J.Biol.Chem_287_27079 |
| PubMedID: 22613724 |
| Title : Varenicline is a potent agonist of the human 5-hydroxytryptamine3 receptor - Lummis_2011_J.Pharmacol.Exp.Ther_339_125 |
| Author(s) : Lummis SC , Thompson AJ , Bencherif M , Lester HA |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 339 :125 , 2011 |
| Abstract : |
| PubMedSearch : Lummis_2011_J.Pharmacol.Exp.Ther_339_125 |
| PubMedID: 21775477 |
| Title : Cys-loop receptor channel blockers also block GLIC - Alqazzaz_2011_Biophys.J_101_2912 |
| Author(s) : Alqazzaz M , Thompson AJ , Price KL , Breitinger HG , Lummis SC |
| Ref : Biophysical Journal , 101 :2912 , 2011 |
| Abstract : |
| PubMedSearch : Alqazzaz_2011_Biophys.J_101_2912 |
| PubMedID: 22208189 |
| Title : Varenicline is a potent agonist of the human 5-hydroxytryptamine3 receptor - Lummis_2011_J.Pharmacol.Exp.Ther_339_125 |
| Author(s) : Lummis SC , Thompson AJ , Bencherif M , Lester HA |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 339 :125 , 2011 |
| Abstract : |
| PubMedSearch : Lummis_2011_J.Pharmacol.Exp.Ther_339_125 |
| PubMedID: 21775477 |
| Title : A cation-pi interaction at a phenylalanine residue in the glycine receptor binding site is conserved for different agonists - Pless_2011_Mol.Pharmacol_79_742 |
| Author(s) : Pless SA , Hanek AP , Price KL , Lynch JW , Lester HA , Dougherty DA , Lummis SC |
| Ref : Molecular Pharmacology , 79 :742 , 2011 |
| Abstract : |
| PubMedSearch : Pless_2011_Mol.Pharmacol_79_742 |
| PubMedID: 21266487 |
| Title : A cation-pi interaction at a phenylalanine residue in the glycine receptor binding site is conserved for different agonists - Pless_2011_Mol.Pharmacol_79_742 |
| Author(s) : Pless SA , Hanek AP , Price KL , Lynch JW , Lester HA , Dougherty DA , Lummis SC |
| Ref : Molecular Pharmacology , 79 :742 , 2011 |
| Abstract : |
| PubMedSearch : Pless_2011_Mol.Pharmacol_79_742 |
| PubMedID: 21266487 |
| Title : Cys-loop receptor channel blockers also block GLIC - Alqazzaz_2011_Biophys.J_101_2912 |
| Author(s) : Alqazzaz M , Thompson AJ , Price KL , Breitinger HG , Lummis SC |
| Ref : Biophysical Journal , 101 :2912 , 2011 |
| Abstract : |
| PubMedSearch : Alqazzaz_2011_Biophys.J_101_2912 |
| PubMedID: 22208189 |
| Title : Identifying the binding site of novel methyllycaconitine (MLA) analogs at alpha4beta2 nicotinic acetylcholine receptors - Quek_2010_ACS.Chem.Neurosci_1_796 |
| Author(s) : Quek GX , Lin D , Halliday JI , Absalom N , Ambrus JI , Thompson AJ , Lochner M , Lummis SC , McLeod MD , Chebib M |
| Ref : ACS Chem Neurosci , 1 :796 , 2010 |
| Abstract : |
| PubMedSearch : Quek_2010_ACS.Chem.Neurosci_1_796 |
| PubMedID: 22778816 |
| Title : Identifying the binding site of novel methyllycaconitine (MLA) analogs at alpha4beta2 nicotinic acetylcholine receptors - Quek_2010_ACS.Chem.Neurosci_1_796 |
| Author(s) : Quek GX , Lin D , Halliday JI , Absalom N , Ambrus JI , Thompson AJ , Lochner M , Lummis SC , McLeod MD , Chebib M |
| Ref : ACS Chem Neurosci , 1 :796 , 2010 |
| Abstract : |
| PubMedSearch : Quek_2010_ACS.Chem.Neurosci_1_796 |
| PubMedID: 22778816 |
| Title : Glutamine 57 at the complementary binding site face is a key determinant of morantel selectivity for {alpha}7 nicotinic receptors - Bartos_2009_J.Biol.Chem_284_21478 |
| Author(s) : Bartos M , Price KL , Lummis SC , Bouzat C |
| Ref : Journal of Biological Chemistry , 284 :21478 , 2009 |
| Abstract : |
| PubMedSearch : Bartos_2009_J.Biol.Chem_284_21478 |
| PubMedID: 19506073 |
| Title : Glutamine 57 at the complementary binding site face is a key determinant of morantel selectivity for {alpha}7 nicotinic receptors - Bartos_2009_J.Biol.Chem_284_21478 |
| Author(s) : Bartos M , Price KL , Lummis SC , Bouzat C |
| Ref : Journal of Biological Chemistry , 284 :21478 , 2009 |
| Abstract : |
| PubMedSearch : Bartos_2009_J.Biol.Chem_284_21478 |
| PubMedID: 19506073 |
| Title : A cation-pi binding interaction with a tyrosine in the binding site of the GABAC receptor - Lummis_2005_Chem.Biol_12_993 |
| Author(s) : Lummis SC , D LB , Harrison NJ , Lester HA , Dougherty DA |
| Ref : Chemical Biology , 12 :993 , 2005 |
| Abstract : |
| PubMedSearch : Lummis_2005_Chem.Biol_12_993 |
| PubMedID: 16183023 |
| Title : A cation-pi binding interaction with a tyrosine in the binding site of the GABAC receptor - Lummis_2005_Chem.Biol_12_993 |
| Author(s) : Lummis SC , D LB , Harrison NJ , Lester HA , Dougherty DA |
| Ref : Chemical Biology , 12 :993 , 2005 |
| Abstract : |
| PubMedSearch : Lummis_2005_Chem.Biol_12_993 |
| PubMedID: 16183023 |
| Title : Nicotinic receptors co-localize with 5-HT(3) serotonin receptors on striatal nerve terminals - Nayak_2000_Neuropharmacol_39_2681 |
| Author(s) : Nayak SV , Ronde P , Spier AD , Lummis SC , Nichols RA |
| Ref : Neuropharmacology , 39 :2681 , 2000 |
| Abstract : |
| PubMedSearch : Nayak_2000_Neuropharmacol_39_2681 |
| PubMedID: 11044738 |
| Title : Nicotinic receptors co-localize with 5-HT(3) serotonin receptors on striatal nerve terminals - Nayak_2000_Neuropharmacol_39_2681 |
| Author(s) : Nayak SV , Ronde P , Spier AD , Lummis SC , Nichols RA |
| Ref : Neuropharmacology , 39 :2681 , 2000 |
| Abstract : |
| PubMedSearch : Nayak_2000_Neuropharmacol_39_2681 |
| PubMedID: 11044738 |
| Title : Actions of nitromethylenes on an alpha-bungarotoxin-sensitive neuronal nicotinic acetylcholine receptor - Buckingham_1995_Neuropharmacol_34_591 |
| Author(s) : Buckingham SD , Balk ML , Lummis SC , Jewess P , Sattelle DB |
| Ref : Neuropharmacology , 34 :591 , 1995 |
| Abstract : |
| PubMedSearch : Buckingham_1995_Neuropharmacol_34_591 |
| PubMedID: 7566494 |
| Title : Actions of nitromethylenes on an alpha-bungarotoxin-sensitive neuronal nicotinic acetylcholine receptor - Buckingham_1995_Neuropharmacol_34_591 |
| Author(s) : Buckingham SD , Balk ML , Lummis SC , Jewess P , Sattelle DB |
| Ref : Neuropharmacology , 34 :591 , 1995 |
| Abstract : |
| PubMedSearch : Buckingham_1995_Neuropharmacol_34_591 |
| PubMedID: 7566494 |
| Title : Actions of vesamicol on an alpha-bungarotoxin-sensitive neuronal nicotinic acetylcholine receptor - Buckingham_1993_J.Exp.Biol_182_255 |
| Author(s) : Buckingham SD , Lummis SC , Balk ML , Schroeder M , Sattelle DB |
| Ref : J Exp Biol , 182 :255 , 1993 |
| Abstract : |
| PubMedSearch : Buckingham_1993_J.Exp.Biol_182_255 |
| PubMedID: 8228781 |
| Title : Actions of vesamicol on an alpha-bungarotoxin-sensitive neuronal nicotinic acetylcholine receptor - Buckingham_1993_J.Exp.Biol_182_255 |
| Author(s) : Buckingham SD , Lummis SC , Balk ML , Schroeder M , Sattelle DB |
| Ref : J Exp Biol , 182 :255 , 1993 |
| Abstract : |
| PubMedSearch : Buckingham_1993_J.Exp.Biol_182_255 |
| PubMedID: 8228781 |
| Title : Actions of a series of bisquaternary compounds on nicotinic acetylcholine receptors in insects: ligand binding and electrophysiological studies - Lummis_1992_Neuropharmacol_31_379 |
| Author(s) : Lummis SC , Buckingham SD , Balk ML , Holyoke CW, Jr. , Sattelle DB |
| Ref : Neuropharmacology , 31 :379 , 1992 |
| Abstract : |
| PubMedSearch : Lummis_1992_Neuropharmacol_31_379 |
| PubMedID: 1522955 |
| Title : Actions of a series of bisquaternary compounds on nicotinic acetylcholine receptors in insects: ligand binding and electrophysiological studies - Lummis_1992_Neuropharmacol_31_379 |
| Author(s) : Lummis SC , Buckingham SD , Balk ML , Holyoke CW, Jr. , Sattelle DB |
| Ref : Neuropharmacology , 31 :379 , 1992 |
| Abstract : |
| PubMedSearch : Lummis_1992_Neuropharmacol_31_379 |
| PubMedID: 1522955 |
| Title : Kappa-bungarotoxin blocks an alpha-bungarotoxin-sensitive nicotinic receptor in the insect central nervous system - Pinnock_1988_Brain.Res_458_45 |
| Author(s) : Pinnock RD , Lummis SC , Chiappinelli VA , Sattelle DB |
| Ref : Brain Research , 458 :45 , 1988 |
| Abstract : |
| PubMedSearch : Pinnock_1988_Brain.Res_458_45 |
| PubMedID: 3208100 |
| Title : The cross-linking reagent dimethyl suberimate modifies the target size of an insect nervous system nicotinic acetylcholine receptor - Lummis_1988_Neurosci.Lett_87_145 |
| Author(s) : Lummis SC , Ellory JC , Sattelle DB |
| Ref : Neuroscience Letters , 87 :145 , 1988 |
| Abstract : |
| PubMedSearch : Lummis_1988_Neurosci.Lett_87_145 |
| PubMedID: 3380333 |
| Title : The cross-linking reagent dimethyl suberimate modifies the target size of an insect nervous system nicotinic acetylcholine receptor - Lummis_1988_Neurosci.Lett_87_145 |
| Author(s) : Lummis SC , Ellory JC , Sattelle DB |
| Ref : Neuroscience Letters , 87 :145 , 1988 |
| Abstract : |
| PubMedSearch : Lummis_1988_Neurosci.Lett_87_145 |
| PubMedID: 3380333 |
| Title : Kappa-bungarotoxin blocks an alpha-bungarotoxin-sensitive nicotinic receptor in the insect central nervous system - Pinnock_1988_Brain.Res_458_45 |
| Author(s) : Pinnock RD , Lummis SC , Chiappinelli VA , Sattelle DB |
| Ref : Brain Research , 458 :45 , 1988 |
| Abstract : |
| PubMedSearch : Pinnock_1988_Brain.Res_458_45 |
| PubMedID: 3208100 |
| Title : Molecular weight estimates of insect cholinergic receptors by radiation inactivation - Lummis_1984_Neurosci.Lett_44_7 |
| Author(s) : Lummis SC , Sattelle DB , Ellory JC |
| Ref : Neuroscience Letters , 44 :7 , 1984 |
| Abstract : |
| PubMedSearch : Lummis_1984_Neurosci.Lett_44_7 |
| PubMedID: 6717855 |
| Title : Molecular weight estimates of insect cholinergic receptors by radiation inactivation - Lummis_1984_Neurosci.Lett_44_7 |
| Author(s) : Lummis SC , Sattelle DB , Ellory JC |
| Ref : Neuroscience Letters , 44 :7 , 1984 |
| Abstract : |
| PubMedSearch : Lummis_1984_Neurosci.Lett_44_7 |
| PubMedID: 6717855 |