Bertrand D

General

Full name : Bertrand Daniel

First name : Daniel

Mail : HiQScreen Sarl, 15, rue de l'Athenee, 1206 Geneva

Zip Code :

City :

Country : Switzerland

Email : Daniel.Bertrand@hiqscreen.com

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References (114)

Title : Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors - Lyukmanova_2016_Sci.Rep_6_30698
Author(s) : Lyukmanova EN , Shulepko MA , Shenkarev ZO , Bychkov ML , Paramonov AS , Chugunov AO , Kulbatskii DS , Arvaniti M , Dolejsi E , Schaer T , Arseniev AS , Efremov RG , Thomsen MS , Dolezal V , Bertrand D , Dolgikh DA , Kirpichnikov MP
Ref : Sci Rep , 6 :30698 , 2016
PubMedID: 27485575

Title : Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues - Wijckmans_2016_PLoS.One_11_e0151183
Author(s) : Wijckmans E , Nys M , Debaveye S , Brams M , Pardon E , Willegems K , Bertrand D , Steyaert J , Efremov R , Ulens C
Ref : PLoS ONE , 11 :e0151183 , 2016
PubMedID: 26999666

Title : Nicotinic acetylcholine receptors as therapeutic targets: Emerging frontiers in basic research and clinical science--Editorial Comments -
Author(s) : Dani JA , Donnelly-Roberts D , Bertrand D
Ref : Biochemical Pharmacology , 97 :351 , 2015
PubMedID: 26074266

Title : Concentration-response relationship of the alpha7 nicotinic acetylcholine receptor agonist FRM-17874 across multiple in vitro and in vivo assays - Stoiljkovic_2015_Biochem.Pharmacol_97(4)_576
Author(s) : Stoiljkovic M , Leventhal L , Chen A , Chen T , Driscoll R , Flood D , Hodgdon H , Hurst R , Nagy D , Piser T , Tang C , Townsend M , Tu Z , Bertrand D , Koenig G , Hajos M
Ref : Biochemical Pharmacology , 97 :576 , 2015
PubMedID: 26206187

Title : Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the alpha7 nicotinic acetylcholine receptor - Spurny_2015_Proc.Natl.Acad.Sci.U.S.A_112_E2543
Author(s) : Spurny R , Debaveye S , Farinha A , Veys K , Vos AM , Gossas T , Atack J , Bertrand S , Bertrand D , Danielson UH , Tresadern G , Ulens C
Ref : Proc Natl Acad Sci U S A , 112 :E2543 , 2015
PubMedID: 25918415

Title : Functional Characterization of AT-1001, an alpha3beta4 Nicotinic Acetylcholine Receptor Ligand, at Human alpha3beta4 and alpha4beta2 nAChR - Zaveri_2015_Nicotine.Tob.Res_17_361
Author(s) : Zaveri NT , Bertrand S , Yasuda D , Bertrand D
Ref : Nicotine Tob Res , 17 :361 , 2015
PubMedID: 25180076

Title : Functional interactions of varenicline and nicotine with nAChR subtypes implicated in cardiovascular control - Rollema_2014_Nicotine.Tob.Res_16_733
Author(s) : Rollema H , Russ C , Lee TC , Hurst RS , Bertrand D
Ref : Nicotine Tob Res , 16 :733 , 2014
PubMedID: 24406270

Title : Discovery of potent positive allosteric modulators of the alpha3beta2 nicotinic acetylcholine receptor by a chemical space walk in ChEMBL - Burgi_2014_ACS.Chem.Neurosci_5_346
Author(s) : Burgi JJ , Awale M , Boss SD , Schaer T , Marger F , Viveros-Paredes JM , Bertrand S , Gertsch J , Bertrand D , Reymond JL
Ref : ACS Chem Neurosci , 5 :346 , 2014
PubMedID: 24593915

Title : Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science--editorial comments -
Author(s) : Dani JA , Donnelly-Roberts D , Bertrand D
Ref : Biochemical Pharmacology , 86 :1041 , 2013
PubMedID: 23684691

Title : Nicotinic acetylcholine receptors: from basic science to therapeutics - Hurst_2013_Pharmacol.Ther_137_22
Author(s) : Hurst RS , Rollema H , Bertrand D
Ref : Pharmacol Ther , 137 :22 , 2013
PubMedID: 22925690

Title : Assembly of a pi-pi stack of ligands in the binding site of an acetylcholine-binding protein - Stornaiuolo_2013_Nat.Commun_4_1875
Author(s) : Stornaiuolo M , De Kloe GE , Rucktooa P , Fish A , van Elk R , Edink ES , Bertrand D , Smit AB , de Esch IJ , Sixma TK
Ref : Nat Commun , 4 :1875 , 2013
PubMedID: 23695669

Title : Importance of the nicotinic acetylcholine receptor system in the prefrontal cortex - Wallace_2013_Biochem.Pharmacol_85_1713
Author(s) : Wallace TL , Bertrand D
Ref : Biochemical Pharmacology , 85 :1713 , 2013
PubMedID: 23628449

Title : Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia - Wallace_2013_Expert.Opin.Ther.Targets_17_139
Author(s) : Wallace TL , Bertrand D
Ref : Expert Opin Ther Targets , 17 :139 , 2013
PubMedID: 23231385

Title : Dimeric alpha-cobratoxin X-ray structure: localization of intermolecular disulfides and possible mode of binding to nicotinic acetylcholine receptors - Osipov_2012_J.Biol.Chem_287_6725
Author(s) : Osipov AV , Rucktooa P , Kasheverov IE , Filkin SY , Starkov VG , Andreeva TV , Sixma TK , Bertrand D , Utkin YN , Tsetlin VI
Ref : Journal of Biological Chemistry , 287 :6725 , 2012
PubMedID: 22223648

Title : Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor - Utkin_2012_J.Biol.Chem_287_27079
Author(s) : Utkin YN , Weise C , Kasheverov IE , Andreeva TV , Kryukova EV , Zhmak MN , Starkov VG , Hoang NA , Bertrand D , Ramerstorfer J , Sieghart W , Thompson AJ , Lummis SC , Tsetlin VI
Ref : Journal of Biological Chemistry , 287 :27079 , 2012
PubMedID: 22613724

Title : alpha7beta2 nicotinic acetylcholine receptors assemble, function, and are activated primarily via their alpha7-alpha7 interfaces - Murray_2012_Mol.Pharmacol_81_175
Author(s) : Murray TA , Bertrand D , Papke RL , George AA , Pantoja R , Srinivasan R , Liu Q , Wu J , Whiteaker P , Lester HA , Lukas RJ
Ref : Molecular Pharmacology , 81 :175 , 2012
PubMedID: 22039094

Title : Molecular actions of smoking cessation drugs at alpha4beta2 nicotinic receptors defined in crystal structures of a homologous binding protein - Billen_2012_Proc.Natl.Acad.Sci.U.S.A_109_9173
Author(s) : Billen B , Spurny R , Brams M , van Elk R , Valera-Kummer S , Yakel JL , Voets T , Bertrand D , Smit AB , Ulens C
Ref : Proc Natl Acad Sci U S A , 109 :9173 , 2012
PubMedID: 22619328

Title : Poster: The conundrum of the alpha5 nicotinic acetylcholine receptor subunit -
Author(s) : Bertrand S , Neveu E , Bertrand D , Gotti C
Ref : Biochemical Pharmacology , 82 :1023 , 2011
PubMedID:

Title : Poster: Discovery of nicotinic acetylcholine receptor ligands in the chemical universe database GDB-13 -
Author(s) : Blum LC , van Deursen R , Brgi J , Reymond JL , Maver M , Bertrand S , Bertrand D
Ref : Biochemical Pharmacology , 82 :1027 , 2011
PubMedID:

Title : Engineering of alpha-conotoxin MII-derived peptides with increased selectivity for native alpha6beta2* nicotinic acetylcholine receptors - Pucci_2011_FASEB.J_25_3775
Author(s) : Pucci L , Grazioso G , Dallanoce C , Rizzi L , De Micheli C , Clementi F , Bertrand S , Bertrand D , Longhi R , De Amici M , Gotti C
Ref : FASEB Journal , 25 :3775 , 2011
PubMedID: 21778325

Title : Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science--Editorial Comments -
Author(s) : Donnelly-Roberts D , Bertrand D , Gopalakrishnan M
Ref : Biochemical Pharmacology , 82 :797 , 2011
PubMedID: 21600889

Title : Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors - Akdemir_2011_Bioorg.Med.Chem_19_6107
Author(s) : Akdemir A , Rucktooa P , Jongejan A , Elk R , Bertrand S , Sixma TK , Bertrand D , Smit AB , Leurs R , de Graaf C , de Esch IJ
Ref : Bioorganic & Medicinal Chemistry , 19 :6107 , 2011
PubMedID: 21920761

Title : Poster: Comparison of pharmacologic properties of AZD3480 and AZD1446 on neuronal nicotinic receptor subtypes -
Author(s) : von Euler G , Bertrand D , Johnson EC
Ref : Biochemical Pharmacology , 82 :1026 , 2011
PubMedID:

Title : Poster: Effects of RG3487 at the alpha7\/beta2 nicotinic acetylcholine receptor expressed in Xenopus oocytes -
Author(s) : Wallace TL , Porter R , Neveu E , Bertrand D
Ref : Biochemical Pharmacology , 82 :1026 , 2011
PubMedID:

Title : NMR structure and action on nicotinic acetylcholine receptors of water-soluble domain of human LYNX1 - Lyukmanova_2011_J.Biol.Chem_286_10618
Author(s) : Lyukmanova EN , Shenkarev ZO , Shulepko MA , Mineev KS , D'Hoedt D , Kasheverov IE , Filkin SY , Krivolapova AP , Janickova H , Dolezal V , Dolgikh DA , Arseniev AS , Bertrand D , Tsetlin VI , Kirpichnikov MP
Ref : Journal of Biological Chemistry , 286 :10618 , 2011
PubMedID: 21252236

Title : RG3487, a novel nicotinic alpha7 receptor partial agonist, improves cognition and sensorimotor gating in rodents - Wallace_2011_J.Pharmacol.Exp.Ther_336_242
Author(s) : Wallace TL , Callahan PM , Tehim A , Bertrand D , Tombaugh G , Wang S , Xie W , Rowe WB , Ong V , Graham E , Terry AV, Jr. , Rodefer JS , Herbert B , Murray M , Porter R , Santarelli L , Lowe DA
Ref : Journal of Pharmacology & Experimental Therapeutics , 336 :242 , 2011
PubMedID: 20959364

Title : The chimeric gene CHRFAM7A, a partial duplication of the CHRNA7 gene, is a dominant negative regulator of alpha7*nAChR function - Araud_2011_Biochem.Pharmacol_82(8)_904
Author(s) : Araud T , Graw S , Berger R , Lee M , Neveu E , Bertrand D , Leonard S
Ref : Biochemical Pharmacology , 82 :904 , 2011
PubMedID: 21718690

Title : Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence - Rollema_2010_Br.J.Pharmacol_160_334
Author(s) : Rollema H , Shrikhande A , Ward KM , Tingley FD, 3rd , Coe JW , O'Neill BT , Tseng E , Wang EQ , Mather RJ , Hurst RS , Williams KE , De Vries M , Cremers T , Bertrand S , Bertrand D
Ref : British Journal of Pharmacology , 160 :334 , 2010
PubMedID: 20331614

Title : Associated proteins: The universal toolbox controlling ligand gated ion channel function - Araud_2010_Biochem.Pharmacol_80_160
Author(s) : Araud T , Wonnacott S , Bertrand D
Ref : Biochemical Pharmacology , 80 :160 , 2010
PubMedID: 20346921

Title : Poster: Functional expression of an alpha5\/beta2 nicotinic acetylcholine receptor -
Author(s) : Araud T , Wanischeck M , Benfante R , Steinlein OK , Fornasari D , Bertrand D , Hoda JC
Ref : Biochemical Pharmacology , 78 :901 , 2009
PubMedID:

Title : Poster: Importance of nicotinic acetylcholine receptors in the visual adverse effects associated with telithromycin -
Author(s) : Bertrand D , Bertrand S , Fernandes P
Ref : Biochemical Pharmacology , 78 :922 , 2009
PubMedID:

Title : Poster: Automated two-electrode voltage clamp for medium-throughput studies of ion channels with non-destructive sample analysis -
Author(s) : Dhoedt D , Tsetlin V , Bertrand S , Bertrand D
Ref : Biochemical Pharmacology , 78 :907 , 2009
PubMedID:

Title : Poster: Novel alpha-7 nAChRs ligands: From virtual screening to functional assays -
Author(s) : Garcia N , Nguyen KT , Bertrand S , Bertrand D , Reymond JL
Ref : Biochemical Pharmacology , 78 :907 , 2009
PubMedID:

Title : Interaction of alpha-conotoxin ImII and its analogs with nicotinic receptors and acetylcholine-binding proteins: additional binding sites on Torpedo receptor - Kasheverov_2009_J.Neurochem_111_934
Author(s) : Kasheverov IE , Zhmak MN , Fish A , Rucktooa P , Khruschov AY , Osipov AV , Ziganshin RH , D'Hoedt D , Bertrand D , Sixma TK , Smit AB , Tsetlin VI
Ref : Journal of Neurochemistry , 111 :934 , 2009
PubMedID: 19712060

Title : Poster: Nicotinic receptor activation increases glutamatergic transmission and plasticity in the rat cerebellum -
Author(s) : Prestori F , Bertrand D , DAngelo E
Ref : Biochemical Pharmacology , 78 :908 , 2009
PubMedID:

Title : Poster: Preclinical properties of the alpha4\/beta2 nAChR partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence -
Author(s) : Rollema H , Shrikhande A , Ward KM , Coe JW , Tseng E , Wang EQ , De Vries M , Cremers THIF , Bertrand S , Bertrand D
Ref : Biochemical Pharmacology , 78 :918 , 2009
PubMedID:

Title : Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis - Ulens_2009_J.Med.Chem_52_2372
Author(s) : Ulens C , Akdemir A , Jongejan A , van Elk R , Bertrand S , Perrakis A , Leurs R , Smit AB , Sixma TK , Bertrand D , de Esch IJ
Ref : Journal of Medicinal Chemistry , 52 :2372 , 2009
PubMedID: 19331415

Title : Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science--editorial perspective -
Author(s) : Bertrand D , Gopalakrishnan M , Donnelly-Roberts D
Ref : Biochemical Pharmacology , 78 :657 , 2009
PubMedID: 19576180

Title : Pudendal motoneurons of the rat located in separated spinal nuclei possess nicotinic acetylcholine receptors having distinct pharmacological profiles - Ogier_2008_Eur.J.Neurosci_28_924
Author(s) : Ogier R , Tribollet E , Bertrand D , Raggenbass M
Ref : European Journal of Neuroscience , 28 :924 , 2008
PubMedID: 18691331

Title : Up-regulation of nicotinic receptors by nicotine varies with receptor subtype - Walsh_2008_J.Biol.Chem_283_6022
Author(s) : Walsh H , Govind AP , Mastro R , Hoda JC , Bertrand D , Vallejo Y , Green WN
Ref : Journal of Biological Chemistry , 283 :6022 , 2008
PubMedID: 18174175

Title : Human nocturnal frontal lobe epilepsy: pharmocogenomic profiles of pathogenic nicotinic acetylcholine receptor beta-subunit mutations outside the ion channel pore - Hoda_2008_Mol.Pharmacol_74_379
Author(s) : Hoda JC , Gu W , Friedli M , Phillips HA , Bertrand S , Antonarakis SE , Goudie D , Roberts R , Scheffer IE , Marini C , Patel J , Berkovic SF , Mulley JC , Steinlein OK , Bertrand D
Ref : Molecular Pharmacology , 74 :379 , 2008
PubMedID: 18456869

Title : Naturally occurring disulfide-bound dimers of three-fingered toxins: a paradigm for biological activity diversification - Osipov_2008_J.Biol.Chem_283_14571
Author(s) : Osipov AV , Kasheverov IE , Makarova YV , Starkov VG , Vorontsova OV , Ziganshin R , Andreeva TV , Serebryakova MV , Benoit A , Hogg RC , Bertrand D , Tsetlin VI , Utkin YN
Ref : Journal of Biological Chemistry , 283 :14571 , 2008
PubMedID: 18381281

Title : [3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]hept ane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain - Anderson_2008_J.Pharmacol.Exp.Ther_324_179
Author(s) : Anderson DJ , Bunnelle W , Surber B , Du J , Surowy C , Tribollet E , Marguerat A , Bertrand D , Gopalakrishnan M
Ref : Journal of Pharmacology & Experimental Therapeutics , 324 :179 , 2008
PubMedID: 17959745

Title : Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment - Bertrand_2008_Mol.Pharmacol_74_1407
Author(s) : Bertrand D , Bertrand S , Cassar S , Gubbins E , Li J , Gopalakrishnan M
Ref : Molecular Pharmacology , 74 :1407 , 2008
PubMedID: 18678621

Title : Partial agonists as therapeutic agents at neuronal nicotinic acetylcholine receptors - Hogg_2007_Biochem.Pharmacol_73_459
Author(s) : Hogg RC , Bertrand D
Ref : Biochemical Pharmacology , 73 :459 , 2007
PubMedID: 16979139

Title : Bacterial expression, NMR, and electrophysiology analysis of chimeric short\/long-chain alpha-neurotoxins acting on neuronal nicotinic receptors - Lyukmanova_2007_J.Biol.Chem_282_24784
Author(s) : Lyukmanova EN , Shenkarev ZO , Schulga AA , Ermolyuk YS , Mordvintsev DY , Utkin YN , Shoulepko MA , Hogg RC , Bertrand D , Dolgikh DA , Tsetlin VI , Kirpichnikov MP
Ref : Journal of Biological Chemistry , 282 :24784 , 2007
PubMedID: 17576769

Title : Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science - editorial comments -
Author(s) : Gopalakrishnan M , Bertrand D , Williams M
Ref : Biochemical Pharmacology , 74 :1091 , 2007
PubMedID: 17889037

Title : Allosteric modulation of nicotinic acetylcholine receptors - Bertrand_2007_Biochem.Pharmacol_74(8)_1155
Author(s) : Bertrand D , Gopalakrishnan M
Ref : Biochemical Pharmacology , 74 :1155 , 2007
PubMedID: 17707779

Title : Reorganization of the nicotinic acetylcholine receptor during desensitization probed with a photoactivatable agonist - Mourot_2006_J.Mol.Neurosci_30_13
Author(s) : Mourot A , Rodrigo J , Bertrand S , Bertrand D , Goeldner M , Kotzyba-Hibert F
Ref : Journal of Molecular Neuroscience , 30 :13 , 2006
PubMedID: 17192607

Title : Alpha-conotoxin analogs with enhanced affinity for nicotinic receptors and acetylcholine-binding proteins - Tsetlin_2006_J.Mol.Neurosci_30_77
Author(s) : Tsetlin VI , Kasheverov IE , Zhmak MN , Utkin YN , Vulfius CA , Smit AB , Bertrand D
Ref : Journal of Molecular Neuroscience , 30 :77 , 2006
PubMedID: 17192636

Title : Acetylcholine-binding proteins: functional and structural homologs of nicotinic acetylcholine receptors - Smit_2006_J.Mol.Neurosci_30_9
Author(s) : Smit AB , Celie PH , Kasheverov IE , Mordvintsev DY , van Nierop P , Bertrand D , Tsetlin V , Sixma TK
Ref : Journal of Molecular Neuroscience , 30 :9 , 2006
PubMedID: 17192605

Title : Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP - Ulens_2006_Proc.Natl.Acad.Sci.U.S.A_103_3615
Author(s) : Ulens C , Hogg RC , Celie PH , Bertrand D , Tsetlin V , Smit AB , Sixma TK
Ref : Proc Natl Acad Sci U S A , 103 :3615 , 2006
PubMedID: 16505382

Title : Engineered site-directed labeling of nicotinic acetylcholine receptors using reactive epibatidine derivatives: appraisal of epibatidine-docking models in neuronal and muscular receptors - Sakr_2006_J.Mol.Neurosci_30_35
Author(s) : Sakr E , Kotzyba-Hibert F , Grande J , Hovius R , Vogel H , Bertrand S , Bertrand D , Goeldner M
Ref : Journal of Molecular Neuroscience , 30 :35 , 2006
PubMedID: 17192618

Title : Probing the reorganization of the nicotinic acetylcholine receptor during desensitization by time-resolved covalent labeling using [3H]AC5, a photoactivatable agonist - Mourot_2006_Mol.Pharmacol_69_452
Author(s) : Mourot A , Rodrigo J , Kotzyba-Hibert F , Bertrand S , Bertrand D , Goeldner M
Ref : Molecular Pharmacology , 69 :452 , 2006
PubMedID: 16269537

Title : Alpha7 neuronal nicotinic acetylcholine receptors are negatively regulated by tyrosine phosphorylation and Src-family kinases - Charpantier_2005_J.Neurosci_25_9836
Author(s) : Charpantier E , Wiesner A , Huh KH , Ogier R , Hoda JC , Allaman G , Raggenbass M , Feuerbach D , Bertrand D , Fuhrer C
Ref : Journal of Neuroscience , 25 :9836 , 2005
PubMedID: 16251431

Title : A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization - Hurst_2005_J.Neurosci_25_4396
Author(s) : Hurst RS , Hajos M , Raggenbass M , Wall TM , Higdon NR , Lawson JA , Rutherford-Root KL , Berkenpas MB , Hoffmann WE , Piotrowski DW , Groppi VE , Allaman G , Ogier R , Bertrand S , Bertrand D , Arneric SP
Ref : Journal of Neuroscience , 25 :4396 , 2005
PubMedID: 15858066

Title : Chronic nicotine exposure upregulates nicotinic receptors by a novel mechanism - Vallejo_2005_J.Neurosci_25_5563
Author(s) : Vallejo YF , Buisson B , Bertrand D , Green WN
Ref : Journal of Neuroscience , 25 :5563 , 2005
PubMedID: 15944384

Title : Functional properties of neuronal nicotinic acetylcholine receptors in the chick retina during development - Lecchi_2005_Eur.J.Neurosci_21_3182
Author(s) : Lecchi M , McIntosh JM , Bertrand S , Safran AB , Bertrand D
Ref : European Journal of Neuroscience , 21 :3182 , 2005
PubMedID: 15978026

Title : Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant - Celie_2005_Nat.Struct.Mol.Biol_12_582
Author(s) : Celie PH , Kasheverov IE , Mordvintsev DY , Hogg RC , van Nierop P , van Elk R , van Rossum-Fikkert SE , Zhmak MN , Bertrand D , Tsetlin V , Sixma TK , Smit AB
Ref : Nat Struct Mol Biol , 12 :582 , 2005
PubMedID: 15951818

Title : Identified spinal motoneurons of young rats possess nicotinic acetylcholine receptors of the heteromeric family - Ogier_2004_Eur.J.Neurosci_20_2591
Author(s) : Ogier R , Liu X , Tribollet E , Bertrand D , Raggenbass M
Ref : European Journal of Neuroscience , 20 :2591 , 2004
PubMedID: 15548202

Title : Nicotinic cholinergic activation of magnocellular endocrine neurons of the hypothalamus. -
Author(s) : Zaninetti M , Tribollet E , Bertrand D , Ogier R , Raggenbass M
Ref : Cholinergic Mechanisms, CRC Press :745 , 2004
PubMedID:

Title : Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: an autoradiographic study in the rat brain - Tribollet_2004_Neurosci_124_405
Author(s) : Tribollet E , Bertrand D , Marguerat A , Raggenbass M
Ref : Neuroscience , 124 :405 , 2004
PubMedID: 14980390

Title : alpha-Conotoxins PnIA and [A10L]PnIA stabilize different states of the chick neuronal alpha7 acetylcholine receptor. -
Author(s) : Hogg RC , Bertrand S , Alewood PF , Adams DJ , Bertrand D
Ref : Cholinergic Mechanisms, CRC Press :591 , 2004
PubMedID:

Title : Neuroscience. What genes tell us about nicotine addiction -
Author(s) : Hogg RC , Bertrand D
Ref : Science , 306 :983 , 2004
PubMedID: 15528431

Title : Nicotinic acetylcholine receptors as drug targets - Hogg_2004_Curr.Drug.Targets.CNS.Neurol.Disord_3_123
Author(s) : Hogg RC , Bertrand D
Ref : Curr Drug Targets CNS Neurol Disord , 3 :123 , 2004
PubMedID: 15078187

Title : Ganglion cells from chick retina display multiple functional nAChR subtypes - Lecchi_2004_Neuroreport_15_307
Author(s) : Lecchi M , Marguerat A , Ionescu A , Pelizzone M , Renaud P , Sommerhalder J , Safran AB , Tribollet E , Bertrand D
Ref : Neuroreport , 15 :307 , 2004
PubMedID: 15076758

Title : Role of spontaneous mutations of neuronal nicotinic acetylcholine receptors in ADNFLE. -
Author(s) : Bertrand D , Favre I , Phillips H , Bertrand S , Berkovic SF , Mulley J
Ref : Cholinergic Mechanisms, CRC Press :481 , 2004
PubMedID:

Title : Candoxin. -
Author(s) : Charpantier E , Nirthanan S , Gopalakrishnakone P , Gwee MC , Khoo HE , Cheah LS , Kini RM , Bertrand D
Ref : Cholinergic Mechanisms, CRC Press :509 , 2004
PubMedID:

Title : Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda - Chimienti_2003_Hum.Mol.Genet_12_3017
Author(s) : Chimienti F , Hogg RC , Plantard L , Lehmann C , Brakch N , Fischer J , Huber M , Bertrand D , Hohl D
Ref : Hum Mol Genet , 12 :3017 , 2003
PubMedID: 14506129

Title : Regulating the regulators: the role of nicotinic acetylcholine receptors in human epilepsy - Hogg_2003_Drug.News.Perspect_16_261
Author(s) : Hogg RC , Bertrand D
Ref : Drug News Perspect , 16 :261 , 2003
PubMedID: 12942156

Title : Alpha-conotoxins PnIA and [A10L]PnIA stabilize different states of the alpha7-L247T nicotinic acetylcholine receptor - Hogg_2003_J.Biol.Chem_278_26908
Author(s) : Hogg RC , Hopping G , Alewood PF , Adams DJ , Bertrand D
Ref : Journal of Biological Chemistry , 278 :26908 , 2003
PubMedID: 12746432

Title : Nicotinic acetylcholine receptors: from structure to brain function - Hogg_2003_Rev.Physiol.Biochem.Pharmacol_147_1
Author(s) : Hogg RC , Raggenbass M , Bertrand D
Ref : Rev Physiol Biochemical Pharmacology , 147 :1 , 2003
PubMedID: 12783266

Title : A three-dimensional multi-electrode array for multi-site stimulation and recording in acute brain slices - Heuschkel_2002_J.Neurosci.Methods_114_135
Author(s) : Heuschkel MO , Fejtl M , Raggenbass M , Bertrand D , Renaud P
Ref : Journal of Neuroscience Methods , 114 :135 , 2002
PubMedID: 11856564

Title : Nicotinic receptors in circuit excitability and epilepsy - Raggenbass_2002_J.Neurobiol_53_580
Author(s) : Raggenbass M , Bertrand D
Ref : Journal of Neurobiology , 53 :580 , 2002
PubMedID: 12436422

Title : Nicotinic cholinergic activation of magnocellular neurons of the hypothalamic paraventricular nucleus - Zaninetti_2002_Neurosci_110_287
Author(s) : Zaninetti M , Tribollet E , Bertrand D , Raggenbass M
Ref : Neuroscience , 110 :287 , 2002
PubMedID: 11958870

Title : Role of neuronal nicotinic receptors in the transmission and processing of information in neurons of the central nervous system - Tribollet_2001_Pharmacol.Biochem.Behav_70_457
Author(s) : Tribollet E , Bertrand D , Raggenbass M
Ref : Pharmacol Biochem Behav , 70 :457 , 2001
PubMedID: 11796145

Title : Neuronal nicotinic receptors: from structure to function - Leonard_2001_Nicotine.Tob.Res_3_203
Author(s) : Leonard S , Bertrand D
Ref : Nicotine Tob Res , 3 :203 , 2001
PubMedID: 11506765

Title : Desensitization of neuronal nicotinic acetylcholine receptors conferred by N-terminal segments of the beta 2 subunit - Bohler_2001_Biochemistry_40_2066
Author(s) : Bohler S , Gay S , Bertrand S , Corringer PJ , Edelstein SJ , Changeux JP , Bertrand D
Ref : Biochemistry , 40 :2066 , 2001
PubMedID: 11329274

Title : A new look at the neuronal nicotinic acetylcholine receptor pharmacophore - Curtis_2000_Eur.J.Pharmacol_393_155
Author(s) : Curtis L , Chiodini F , Spang JE , Bertrand S , Patt JT , Westera G , Bertrand D
Ref : European Journal of Pharmacology , 393 :155 , 2000
PubMedID: 10771009

Title : Magnocellular neurons of the rat supraoptic nucleus are endowed with functional nicotinic acetylcholine receptors - Zaninetti_2000_Neurosci_95_319
Author(s) : Zaninetti M , Blanchet C , Tribollet E , Bertrand D , Raggenbass M
Ref : Neuroscience , 95 :319 , 2000
PubMedID: 10658610

Title : The unusual nature of epibatidine responses at the alpha4beta2 nicotinic acetylcholine receptor - Buisson_2000_Neuropharmacol_39_2561
Author(s) : Buisson B , Vallejo YF , Green WN , Bertrand D
Ref : Neuropharmacology , 39 :2561 , 2000
PubMedID: 11044727

Title : Neuronal nicotinic acetylcholine receptors: from the gene to the disease - Weiland_2000_Behav.Brain.Res_113_43
Author(s) : Weiland S , Bertrand D , Leonard S
Ref : Behavioural Brain Research , 113 :43 , 2000
PubMedID: 10942031

Title : Neuronal nicotinic acetylcholine receptors from Drosophila: two different types of alpha subunits coassemble within the same receptor complex - Schulz_2000_J.Neurochem_74_2537
Author(s) : Schulz R , Bertrand S , Chamaon K , Smalla KH , Gundelfinger ED , Bertrand D
Ref : Journal of Neurochemistry , 74 :2537 , 2000
PubMedID: 10820216

Title : Neuronal Nicotinic Acetylcholine Receptors: From Biophysical Properties to Human Diseases -
Author(s) : Buisson B , Picard F , Bertrand D
Ref : Handbook of Experimental Pharmacology , 144 :271 , 2000
PubMedID:

Title : Presence of functional neuronal nicotinic acetylcholine receptors in brainstem motoneurons of the rat - Zaninetti_1999_Eur.J.Neurosci_11_2737
Author(s) : Zaninetti M , Tribollet E , Bertrand D , Raggenbass M
Ref : European Journal of Neuroscience , 11 :2737 , 1999
PubMedID: 10457170

Title : Molecular basis of the charge selectivity of nicotinic acetylcholine receptor and related ligand-gated ion channels - Corringer_1999_Novartis.Found.Symp_225_215
Author(s) : Corringer PJ , Bertrand S , Galzi JL , Devillers-Thiery A , Changeux JP , Bertrand D
Ref : Novartis Found Symp , 225 :215 , 1999
PubMedID: 10472058

Title : Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor - Corringer_1999_Neuron_22_831
Author(s) : Corringer PJ , Bertrand S , Galzi JL , Devillers-Thiery A , Changeux JP , Bertrand D
Ref : Neuron , 22 :831 , 1999
PubMedID: 10230802

Title : International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits -
Author(s) : Lukas RJ , Changeux JP , Le Novere N , Albuquerque EX , Balfour DJ , Berg DK , Bertrand D , Chiappinelli VA , Clarke PB , Collins AC , Dani JA , Grady SR , Kellar KJ , Lindstrom JM , Marks MJ , Quik M , Taylor P , Wonnacott S
Ref : Pharmacol Rev , 51 :397 , 1999
PubMedID: 10353988

Title : Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors - Corringer_1998_J.Neurosci_18_648
Author(s) : Corringer PJ , Bertrand S , Bohler S , Edelstein SJ , Changeux JP , Bertrand D
Ref : Journal of Neuroscience , 18 :648 , 1998
PubMedID: 9425007

Title : Effects of atracurium, a neuromuscular blocking agent, on reconstituted human neuronal nicotinic acetylcholine receptors -
Author(s) : Chiodini F , Bertrand S , Tassonyi E , Muller D , Bertrand D
Ref : Journal de Physiologie (Paris) , 92 :420 , 1998
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Title : Critical elements determining diversity in agonist binding and desensitization of neuronal nAChR -
Author(s) : Corringer PJ , Bertrand S , Bohler S , Edelstein SJ , Bertrand D , Changeux JP
Ref : Journal de Physiologie (Paris) , 92 :424 , 1998
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Title : Artificial toxins to explore new receptors? -
Author(s) : Menez A , Mourier G , Kessler P , Ducancel F , Bertrand D , Corringer PJ , Changeux JP , Servent D
Ref : Journal de Physiologie (Paris) , 92 :468 , 1998
PubMedID:

Title : D alpha3, a new functional alpha subunit of nicotinic acetylcholine receptors from Drosophila - Schulz_1998_J.Neurochem_71_853
Author(s) : Schulz R , Sawruk E , Mulhardt C , Bertrand S , Baumann A , Phannavong B , Betz H , Bertrand D , Gundelfinger ED , Schmitt B
Ref : Journal of Neurochemistry , 71 :853 , 1998
PubMedID: 9681478

Title : Regulation of desensitization by beta subunit in neuronal nAchR -
Author(s) : Bohler S , Corringer PJ , Changeux JP , Bertrand S , Bertrand D , Edelstein SJ
Ref : Journal de Physiologie (Paris) , 92 :414 , 1998
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Title : Human neuronal nicotinic acetylcholine receptors (nAChRs) may participate in the sexual dimorphism functionality of the brain -
Author(s) : Buisson B , Bertrand S , Bertrand D
Ref : Journal de Physiologie (Paris) , 92 :416 , 1998
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Title : Only snake curaremimetic toxins with a fifth disulfide bond have high affinity for the neuronal alpha7 nicotinic receptor - Servent_1997_J.Biol.Chem_272_24279
Author(s) : Servent D , Winckler-Dietrich V , Hu HY , Kessler P , Drevet P , Bertrand D , Menez A
Ref : Journal of Biological Chemistry , 272 :24279 , 1997
PubMedID: 9305882

Title : Paradoxical allosteric effects of competitive inhibitors on neuronal alpha7 nicotinic receptor mutants - Bertrand_1997_Neuroreport_8_3591
Author(s) : Bertrand S , Devillers-Thiery A , Palma E , Buisson B , Edelstein SJ , Corringer PJ , Changeux JP , Bertrand D
Ref : Neuroreport , 8 :3591 , 1997
PubMedID: 9427332

Title : Human alpha4beta2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study - Buisson_1996_J.Neurosci_16_7880
Author(s) : Buisson B , Gopalakrishnan M , Arneric SP , Sullivan JP , Bertrand D
Ref : Journal of Neuroscience , 16 :7880 , 1996
PubMedID: 8987816

Title : A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions - Edelstein_1996_Biol.Cybern_75_361
Author(s) : Edelstein SJ , Schaad O , Henry E , Bertrand D , Changeux JP
Ref : Biological Cybernetics , 75 :361 , 1996
PubMedID: 8983160

Title : Stable expression and pharmacological properties of the human alpha 7 nicotinic acetylcholine receptor - Gopalakrishnan_1995_Eur.J.Pharmacol_290_237
Author(s) : Gopalakrishnan M , Buisson B , Touma E , Giordano T , Campbell JE , Hu IC , Donnelly-Roberts D , Arneric SP , Bertrand D , Sullivan JP
Ref : European Journal of Pharmacology , 290 :237 , 1995
PubMedID: 7589218

Title : Physiological properties of neuronal nicotinic receptors reconstituted from the vertebrate beta 2 subunit and Drosophila alpha subunits - Bertrand_1994_Eur.J.Neurosci_6_869
Author(s) : Bertrand D , Ballivet M , Gomez M , Bertrand S , Phannavong B , Gundelfinger ED
Ref : European Journal of Neuroscience , 6 :869 , 1994
PubMedID: 8075828

Title : Pharmacology and biophysical properties of alpha 7 and alpha 7-alpha 8 alpha-bungarotoxin receptor subtypes immunopurified from the chick optic lobe - Gotti_1994_Eur.J.Neurosci_6_1281
Author(s) : Gotti C , Hanke W , Maury K , Moretti M , Ballivet M , Clementi F , Bertrand D
Ref : European Journal of Neuroscience , 6 :1281 , 1994
PubMedID: 7981870

Title : Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels -
Author(s) : Devillers-Thiery A , Galzi JL , Eisele JL , Bertrand S , Bertrand D , Changeux JP
Ref : J Membr Biol , 136 :97 , 1993
PubMedID: 7508983

Title : Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities - Eisele_1993_Nature_366_479
Author(s) : Eisele JL , Bertrand S , Galzi JL , Devillers-Thiery A , Changeux JP , Bertrand D
Ref : Nature , 366 :479 , 1993
PubMedID: 8247158

Title : Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor - Bertrand_1993_Proc.Natl.Acad.Sci.U.S.A_90_6971
Author(s) : Bertrand D , Galzi JL , Devillers-Thiery A , Bertrand S , Changeux JP
Ref : Proc Natl Acad Sci U S A , 90 :6971 , 1993
PubMedID: 7688468

Title : Stratification of the channel domain in neurotransmitter receptors - Bertrand_1993_Curr.Opin.Cell.Biol_5_688
Author(s) : Bertrand D , Galzi JL , Devillers-Thiery A , Bertrand S , Changeux JP
Ref : Current Opinion in Cell Biology , 5 :688 , 1993
PubMedID: 7504932

Title : Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic - Galzi_1992_Nature_359_500
Author(s) : Galzi JL , Devillers-Thiery A , Hussy N , Bertrand S , Changeux JP , Bertrand D
Ref : Nature , 359 :500 , 1992
PubMedID: 1383829

Title : Methyl lycaconitine: A novel nicotinic antagonist - Drasdo_1992_Mol.Cell.Neurosci_3_237
Author(s) : Drasdo A , Caulfield M , Bertrand D , Bertrand S , Wonnacott S
Ref : Molecular & Cellular Neurosciences , 3 :237 , 1992
PubMedID: 19912865

Title : Stratified organization of the nicotinic acetylcholine receptor channel - Devillers-Thiery_1992_Neuroreport_3_1001
Author(s) : Devillers-Thiery A , Galzi JL , Bertrand S , Changeux JP , Bertrand D
Ref : Neuroreport , 3 :1001 , 1992
PubMedID: 1282832

Title : New mutants to explore nicotinic receptor functions -
Author(s) : Changeux JP , Devillers-Thiery A , Galzi JL , Bertrand D
Ref : Trends in Pharmacological Sciences , 13 :299 , 1992
PubMedID: 1384213

Title : The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis -
Author(s) : Changeux JP , Galzi JL , Devillers-Thiery A , Bertrand D
Ref : Q Rev Biophys , 25 :395 , 1992
PubMedID: 1293635

Title : Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain - Bertrand_1992_Proc.Natl.Acad.Sci.U.S.A_89_1261
Author(s) : Bertrand D , Devillers-Thiery A , Revah F , Galzi JL , Hussy N , Mulle C , Bertrand S , Ballivet M , Changeux JP
Ref : Proc Natl Acad Sci U S A , 89 :1261 , 1992
PubMedID: 1741378

Title : Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis - Galzi_1991_FEBS.Lett_294_198
Author(s) : Galzi JL , Bertrand D , Devillers-Thiery A , Revah F , Bertrand S , Changeux JP
Ref : FEBS Letters , 294 :198 , 1991
PubMedID: 1756861

Title : Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor - Revah_1991_Nature_353_846
Author(s) : Revah F , Bertrand D , Galzi JL , Devillers-Thiery A , Mulle C , Hussy N , Bertrand S , Ballivet M , Changeux JP
Ref : Nature , 353 :846 , 1991
PubMedID: 1719423