Vermillion M

Title : Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys - Mackman_2023_J.Med.Chem_66_11701

Author(s) : Mackman RL , Kalla RV , Babusis D , Pitts J , Barrett KT , Chun K , Du Pont V , Rodriguez L , Moshiri J , Xu Y , Lee M , Lee G , Bleier B , Nguyen AQ , O'Keefe BM , Ambrosi A , Cook M , Yu J , Dempah KE , Bunyan E , Riola NC , Lu X , Liu R , Davie A , Hsiang TY , Dearing J , Vermillion M , Gale M, Jr. , Niedziela-Majka A , Feng JY , Hedskog C , Bilello JP , Subramanian R , Cihlar T

Ref : Journal of Medicinal Chemistry , 66 :11701 , 2023

Abstract :

PubMedSearch : Mackman_2023_J.Med.Chem_66_11701

PubMedID: 37596939

Title : Linker Architectures as Steric Auxiliaries for Altering Enzyme-Mediated Payload Release from Bioconjugates - Giese_2021_Bioconjug.Chem__

Author(s) : Giese M , Davis PD , Woodman RH , Hermanson G , Pokora A , Vermillion M

Ref : Bioconjug Chem , : , 2021

Abstract :

PubMedSearch : Giese_2021_Bioconjug.Chem__

PubMedID: 34587447

Vermillion M

References (2)

1. Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys - Mackman_2023_J.Med.Chem_66_11701

2. Linker Architectures as Steric Auxiliaries for Altering Enzyme-Mediated Payload Release from Bioconjugates - Giese_2021_Bioconjug.Chem__