Weiner L

General

Full name : Weiner Lev M

First name : Lev M

Mail : Weizmann Institute of Science, Rehovot

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Country : Israel

Email : lev.weiner@weizmann.ac.il

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References (31)

Title : Why is binding of a divalent metal cation to a structural motif containing four carboxylate residues not accompanied by a conformational change? - Lushchekina_2024_Protein.Sci_33_e5206
Author(s) : Lushchekina S , Weiner L , Ashani Y , Emrizal R , Firdaus-Raih M , Silman I , Sussman JL
Ref : Protein Science , 33 :e5206 , 2024
Abstract :
PubMedSearch : Lushchekina_2024_Protein.Sci_33_e5206
PubMedID: 39548604
Gene_locus related to this paper: torca-ACHE

Title : Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif - Silman_2021_Protein.Sci_30_966
Author(s) : Silman I , Shnyrov VL , Ashani Y , Roth E , Nicolas A , Sussman JL , Weiner L
Ref : Protein Science , 30 :966 , 2021
Abstract :
PubMedSearch : Silman_2021_Protein.Sci_30_966
PubMedID: 33686648
Gene_locus related to this paper: torca-ACHE

Title : Generation of Reactive Oxygen Species by Photosensitizers and their Modes of Action on Proteins - Bilkis_2018_Curr.Med.Chem_25_5528
Author(s) : Bilkis I , Silman I , Weiner L
Ref : Curr Med Chem , 25 :5528 , 2018
Abstract :
PubMedSearch : Bilkis_2018_Curr.Med.Chem_25_5528
PubMedID: 29303072

Title : The Impact of Crystallization Conditions on Structure-Based Drug Design: A Case Study on the Methylene Blue\/Acetylcholinesterase Complex - Dym_2016_Protein.Sci_25_1096
Author(s) : Dym O , Song W , Felder CE , Roth E , Shnyrov V , Ashani Y , Xu Y , Joosten RP , Weiner L , Sussman JL , Silman I
Ref : Protein Science , 25 :1096 , 2016
Abstract :
PubMedSearch : Dym_2016_Protein.Sci_25_1096
PubMedID: 26990888
Gene_locus related to this paper: torca-ACHE

Title : The specific interaction of the photosensitizer methylene blue with acetylcholinesterase provides a model system for studying the molecular consequences of photodynamic therapy - Silman_2013_Chem.Biol.Interact_203_63
Author(s) : Silman I , Roth E , Paz A , Triquigneaux MM , Ehrenshaft M , Xu Y , Shnyrov VL , Sussman JL , Deterding LJ , Ashani Y , Mason RP , Weiner L
Ref : Chemico-Biological Interactions , 203 :63 , 2013
Abstract :
PubMedSearch : Silman_2013_Chem.Biol.Interact_203_63
PubMedID: 23159732

Title : Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen: identification of N-formylkynurenine tryptophan derivatives within the active-site gorge of its complex with the photosensitizer Methylene Blue - Triquigneaux_2012_Biochem.J_448_83
Author(s) : Triquigneaux MM , Ehrenshaft M , Roth E , Silman I , Ashani Y , Mason RP , Weiner L , Deterding LJ
Ref : Biochemical Journal , 448 :83 , 2012
Abstract :
PubMedSearch : Triquigneaux_2012_Biochem.J_448_83
PubMedID: 22888904

Title : Structural and functional characterization of the interaction of the photosensitizing probe methylene blue with Torpedo californica acetylcholinesterase - Paz_2012_Protein.Sci_21_1138
Author(s) : Paz A , Roth E , Ashani Y , Xu Y , Shnyrov VL , Sussman JL , Silman I , Weiner L
Ref : Protein Science , 21 :1138 , 2012
Abstract :
PubMedSearch : Paz_2012_Protein.Sci_21_1138
PubMedID: 22674800
Gene_locus related to this paper: torca-ACHE

Title : Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen - Weiner_2011_Photochem.Photobiol_87_308
Author(s) : Weiner L , Roth E , Silman I
Ref : Photochem Photobiol , 87 :308 , 2011
Abstract :
PubMedSearch : Weiner_2011_Photochem.Photobiol_87_308
PubMedID: 21155827

Title : Stabilization of Torpedo californica acetylcholinesterase by reversible inhibitors - Weiner_2009_Biochemistry_48_563
Author(s) : Weiner L , Shnyrov VL , Konstantinovskii L , Roth E , Ashani Y , Silman I
Ref : Biochemistry , 48 :563 , 2009
Abstract :
PubMedSearch : Weiner_2009_Biochemistry_48_563
PubMedID: 19115961

Title : Biophysical characterization of the unstructured cytoplasmic domain of the human neuronal adhesion protein neuroligin 3 - Paz_2008_Biophys.J_95_1928
Author(s) : Paz A , Zeev-Ben-Mordehai T , Lundqvist M , Sherman E , Mylonas E , Weiner L , Haran G , Svergun DI , Mulder FA , Sussman JL , Silman I
Ref : Biophysical Journal , 95 :1928 , 2008
Abstract :
PubMedSearch : Paz_2008_Biophys.J_95_1928
PubMedID: 18456828

Title : Poster (18) Partially unfolded states of acetylcholinesterase: rule or exception? -
Author(s) : Weiner L
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :330 , 2004
PubMedID:

Title : Stabilization of a metastable state of Torpedo californica acetylcholinesterase by chemical chaperones - Millard_2003_Protein.Sci_12_2337
Author(s) : Millard CB , Shnyrov VL , Newstead S , Shin I , Roth E , Silman I , Weiner L
Ref : Protein Science , 12 :2337 , 2003
Abstract :
PubMedSearch : Millard_2003_Protein.Sci_12_2337
PubMedID: 14500892

Title : Thermal denaturation of Bungarus fasciatus acetylcholinesterase: Is aggregation a driving force in protein unfolding? - Shin_2002_Protein.Sci_11_2022
Author(s) : Shin I , Wachtel E , Roth E , Bon C , Silman I , Weiner L
Ref : Protein Science , 11 :2022 , 2002
Abstract :
PubMedSearch : Shin_2002_Protein.Sci_11_2022
PubMedID: 12142456

Title : Enhanced free radical scavenging and decreased lipid peroxidation in the rat fetal brain after treatment with ethyl docosahexaenoate - Green_2001_Biochim.Biophys.Acta_1532_203
Author(s) : Green P , Glozman S , Weiner L , Yavin E
Ref : Biochimica & Biophysica Acta , 1532 :203 , 2001
Abstract :
PubMedSearch : Green_2001_Biochim.Biophys.Acta_1532_203
PubMedID: 11470241

Title : A Structural Motif of Acetylcholinesterase That Promotes Amyloid beta-Peptide Fibril Formation - De Ferrari_2001_Biochemistry_40_10447
Author(s) : De Ferrari GV , Canales MA , Shin I , Weiner L , Silman I , Inestrosa NC
Ref : Biochemistry , 40 :10447 , 2001
Abstract :
PubMedSearch : De Ferrari_2001_Biochemistry_40_10447
PubMedID: 11523986

Title : S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties - Rabinkov_2000_Biochim.Biophys.Acta_1499_144
Author(s) : Rabinkov A , Miron T , Mirelman D , Wilchek M , Glozman S , Yavin E , Weiner L
Ref : Biochimica & Biophysica Acta , 1499 :144 , 2000
Abstract :
PubMedSearch : Rabinkov_2000_Biochim.Biophys.Acta_1499_144
PubMedID: 11118647

Title : Ethyl docosahexaenoic acid administration during intrauterine life enhances prostanoid production and reduces free radicals generation in the fetal rat brain -
Author(s) : Glozman S , Green P , Kamensky B , Weiner L , Yavin E
Ref : Lipids , 34 Suppl :S247 , 1999
PubMedID: 10419167

Title : Targeted cross-linking of a molten globule form of acetylcholinesterase by the virucidal agent hypericin - Weiner_1999_Biochemistry_38_11401
Author(s) : Weiner L , Roth E , Mazur Y , Silman I
Ref : Biochemistry , 38 :11401 , 1999
Abstract :
PubMedSearch : Weiner_1999_Biochemistry_38_11401
PubMedID: 10471290

Title : Membrane-Promoted Unfolding of Torpedo Californica and Bungarus Fasciatus Acetylcholinesterase -
Author(s) : Shin I , Silman I , Bon C , Weiner L
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :438 , 1998
PubMedID:

Title : Liposome-catalyzed unfolding of acetylcholinesterase from Bungarus fasciatus - Shin_1998_Biochemistry_37_4310
Author(s) : Shin I , Silman I , Bon C , Weiner L
Ref : Biochemistry , 37 :4310 , 1998
Abstract :
PubMedSearch : Shin_1998_Biochemistry_37_4310
PubMedID: 9556345

Title : Membrane-promoted unfolding of acetylcholinesterase: a possible mechanism for insertion into the lipid bilayer - Shin_1997_Proc.Natl.Acad.Sci.U.S.A_94_2848
Author(s) : Shin I , Kreimer DI , Silman I , Weiner L
Ref : Proceedings of the National Academy of Sciences of the United States of America , 94 :2848 , 1997
Abstract :
PubMedSearch : Shin_1997_Proc.Natl.Acad.Sci.U.S.A_94_2848
PubMedID: 9096309

Title : Two partially unfolded states of Torpedo californica acetylcholinesterase - Kreimer_1996_Protein.Sci_5_1852
Author(s) : Kreimer DI , Shin I , Shnyrov VL , Villar E , Silman I , Weiner L
Ref : Protein Science , 5 :1852 , 1996
Abstract :
PubMedSearch : Kreimer_1996_Protein.Sci_5_1852
PubMedID: 8880909

Title : Interaction of partially unfolded forms of Torpedo acetylcholinesterase with liposomes - Shin_1996_Prot.Sci_5_42
Author(s) : Shin I , Silman I , Weiner L
Ref : Protein Science , 5 :42 , 1996
Abstract :
PubMedSearch : Shin_1996_Prot.Sci_5_42
PubMedID: 8771195

Title : Irreversible thermal denaturation of Torpedo californica acetylcholinesterase - Kreimer_1995_Prot.Sci_4_2349
Author(s) : Kreimer DI , Shnyrov VL , Villar E , Silman I , Weiner L
Ref : Protein Science , 4 :2349 , 1995
Abstract :
PubMedSearch : Kreimer_1995_Prot.Sci_4_2349
PubMedID: 8563632

Title : Quantitative determination of thiol groups in low and high molecular weight compounds by electron paramagnetic resonance -
Author(s) : Weiner L
Ref : Methods Enzymol , 251 :87 , 1995
PubMedID: 7651235

Title : Studies on Partially Unfolded States of Torpedo californica Acetylcholinesterase -
Author(s) : Silman I , Kreimer DI , Shin I , Dolginova EA , Roth E , Goldfarb D , Szosenfogel R , Raves ML , Sussman JL , Borochov N , Weiner L
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :77 , 1995
PubMedID:

Title : A metastable state of Torpedo californica acetylcholinesterase generated by modification with organomercurials - Kreimer_1994_Biochemistry_33_14407
Author(s) : Kreimer DI , Dolginova EA , Raves ML , Sussman JL , Silman I , Weiner L
Ref : Biochemistry , 33 :14407 , 1994
Abstract :
PubMedSearch : Kreimer_1994_Biochemistry_33_14407
PubMedID: 7981200
Gene_locus related to this paper: torca-ACHE

Title : Oxidative stress transforms acetylcholinesterase to a molten-globule-like state - Weiner_1994_Biochem.Biophys.Res.Commun_198_915
Author(s) : Weiner L , Kreimer D , Roth E , Silman I
Ref : Biochemical & Biophysical Research Communications , 198 :915 , 1994
Abstract :
PubMedSearch : Weiner_1994_Biochem.Biophys.Res.Commun_198_915
PubMedID: 8117296

Title : A molten globule of Torpedo acetylcholinesterase undergoes thiol-disulfide exchange - Eichler_1994_J.Biol.Chem_269_30093
Author(s) : Eichler J , Kreimer DI , Varon L , Silman I , Weiner L
Ref : Journal of Biological Chemistry , 269 :30093 , 1994
Abstract :
PubMedSearch : Eichler_1994_J.Biol.Chem_269_30093
PubMedID: 7982909

Title : Two-state transition between molten globule and unfolded states of acetylcholinesterase as monitored by electron paramagnetic resonance spectroscopy - Kreimer_1994_Proc.Natl.Acad.Sci.U.S.A_91_12145
Author(s) : Kreimer DI , Szosenfogel R , Goldfarb D , Silman I , Weiner L
Ref : Proceedings of the National Academy of Sciences of the United States of America , 91 :12145 , 1994
Abstract :
PubMedSearch : Kreimer_1994_Proc.Natl.Acad.Sci.U.S.A_91_12145
PubMedID: 7991597

Title : Chemical modification of Torpedo acetylcholinesterase by disulfides: appearance of a molten globule state - Dolginova_1992_Biochemistry_31_12248
Author(s) : Dolginova EA , Roth E , Silman I , Weiner L
Ref : Biochemistry , 31 :12248 , 1992
Abstract :
PubMedSearch : Dolginova_1992_Biochemistry_31_12248
PubMedID: 1333796