Full name : Inestrosa Nibaldo C
First name : Nibaldo Cantin
Mail : Catholic University of Chile, Dept of Cell & Molecular Biology, Faculty of Biological Sciences, Alameda 340, Santiago
Zip Code :
City :
Country : Chile
Email : ninestrosa@bio.puc.cl
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Website : \/\/es.wikipedia.org\/wiki\/Nibaldo_Inestrosa_Cant\%C3\%ADn
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Comment
Title : Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP\/PS1 Mice - Viayna_2021_J.Med.Chem_64_812 |
Author(s) : Viayna E , Coquelle N , Cieslikiewicz-Bouet M , Cisternas P , Oliva CA , Sanchez-Lopez E , Ettcheto M , Bartolini M , De Simone A , Ricchini M , Rendina M , Pons M , Firuzi O , Perez B , Saso L , Andrisano V , Nachon F , Brazzolotto X , Garcia ML , Camins A , Silman I , Jean L , Inestrosa NC , Colletier JP , Renard PY , Munoz-Torrero D |
Ref : Journal of Medicinal Chemistry , 64 :812 , 2021 |
Abstract : |
PubMedSearch : Viayna_2021_J.Med.Chem_64_812 |
PubMedID: 33356266 |
Gene_locus related to this paper: human-ACHE |
Title : Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer's Disease - Friedli_2021_Molecules_26_ |
Author(s) : Friedli MJ , Inestrosa NC |
Ref : Molecules , 26 : , 2021 |
Abstract : |
PubMedSearch : Friedli_2021_Molecules_26_ |
PubMedID: 34770940 |
Title : Modulating Wnt signaling at the root: Porcupine and Wnt acylation - Torres_2019_Pharmacol.Ther_198_34 |
Author(s) : Torres VI , Godoy JA , Inestrosa NC |
Ref : Pharmacol Ther , 198 :34 , 2019 |
Abstract : |
PubMedSearch : Torres_2019_Pharmacol.Ther_198_34 |
PubMedID: 30790642 |
Title : Rhein-Huprine Derivatives Reduce Cognitive Impairment, Synaptic Failure and Amyloid Pathology in AbetaPPswe\/PS-1 Mice of Different Ages - Serrano_2016_Curr.Alzheimer.Res_13_1017 |
Author(s) : Serrano FG , Tapia-Rojas C , Carvajal FJ , Cisternas P , Viayna E , Sola I , Munoz-Torrero D , Inestrosa NC |
Ref : Curr Alzheimer Res , 13 :1017 , 2016 |
Abstract : |
PubMedSearch : Serrano_2016_Curr.Alzheimer.Res_13_1017 |
PubMedID: 26502813 |
Title : The soluble extracellular fragment of neuroligin-1 targets Abeta oligomers to the postsynaptic region of excitatory synapses - Dinamarca_2015_Biochem.Biophys.Res.Commun_466_66 |
Author(s) : Dinamarca MC , Di Luca M , Godoy JA , Inestrosa NC |
Ref : Biochemical & Biophysical Research Communications , 466 :66 , 2015 |
Abstract : |
PubMedSearch : Dinamarca_2015_Biochem.Biophys.Res.Commun_466_66 |
PubMedID: 26325471 |
Title : Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents - Viayna_2014_J.Med.Chem_57_2549 |
Author(s) : Viayna E , Sola I , Bartolini M , De Simone A , Tapia-Rojas C , Serrano FG , Sabate R , Juarez-Jimenez J , Perez B , Luque FJ , Andrisano V , Clos MV , Inestrosa NC , Munoz-Torrero D |
Ref : Journal of Medicinal Chemistry , 57 :2549 , 2014 |
Abstract : |
PubMedSearch : Viayna_2014_J.Med.Chem_57_2549 |
PubMedID: 24568372 |
Title : Tetrahydrohyperforin increases adult hippocampal neurogenesis in wild-type and APPswe\/PS1DeltaE9 mice - Abbott_2013_J.Alzheimers.Dis_34_873 |
Author(s) : Abbott AC , Calderon Toledo C , Aranguiz FC , Inestrosa NC , Varela-Nallar L |
Ref : J Alzheimers Dis , 34 :873 , 2013 |
Abstract : |
PubMedSearch : Abbott_2013_J.Alzheimers.Dis_34_873 |
PubMedID: 23302657 |
Title : Wnt signaling in the regulation of adult hippocampal neurogenesis - Varela-Nallar_2013_Front.Cell.Neurosci_7_100 |
Author(s) : Varela-Nallar L , Inestrosa NC |
Ref : Front Cell Neurosci , 7 :100 , 2013 |
Abstract : |
PubMedSearch : Varela-Nallar_2013_Front.Cell.Neurosci_7_100 |
PubMedID: 23805076 |
Title : Peroxisome proliferators reduce spatial memory impairment, synaptic failure, and neurodegeneration in brains of a double transgenic mice model of Alzheimer's disease - Inestrosa_2013_J.Alzheimers.Dis_33_941 |
Author(s) : Inestrosa NC , Carvajal FJ , Zolezzi JM , Tapia-Rojas C , Serrano F , Karmelic D , Toledo EM , Toro A , Toro J , Santos MJ |
Ref : J Alzheimers Dis , 33 :941 , 2013 |
Abstract : |
PubMedSearch : Inestrosa_2013_J.Alzheimers.Dis_33_941 |
PubMedID: 23109558 |
Title : Postsynaptic Receptors for Amyloid-beta Oligomers as Mediators of Neuronal Damage in Alzheimer's Disease - Dinamarca_2012_Front.Physiol_3_464 |
Author(s) : Dinamarca MC , Rios JA , Inestrosa NC |
Ref : Front Physiol , 3 :464 , 2012 |
Abstract : |
PubMedSearch : Dinamarca_2012_Front.Physiol_3_464 |
PubMedID: 23267328 |
Title : SIRT1 regulates dendritic development in hippocampal neurons - Codocedo_2012_PLoS.One_7_e47073 |
Author(s) : Codocedo JF , Allard C , Godoy JA , Varela-Nallar L , Inestrosa NC |
Ref : PLoS ONE , 7 :e47073 , 2012 |
Abstract : |
PubMedSearch : Codocedo_2012_PLoS.One_7_e47073 |
PubMedID: 23056585 |
Title : Wnt-5a is a synaptogenic factor with neuroprotective properties against Abeta toxicity - Varela-Nallar_2012_Neurodegener.Dis_10_23 |
Author(s) : Varela-Nallar L , Parodi J , Farias GG , Inestrosa NC |
Ref : Neurodegener Dis , 10 :23 , 2012 |
Abstract : |
PubMedSearch : Varela-Nallar_2012_Neurodegener.Dis_10_23 |
PubMedID: 22261402 |
Title : Frizzled receptors in neurons: from growth cones to the synapse - Varela-Nallar_2012_Cytoskeleton.(Hoboken)_69_528 |
Author(s) : Varela-Nallar L , Ramirez VT , Gonzalez-Billault C , Inestrosa NC |
Ref : Cytoskeleton (Hoboken) , 69 :528 , 2012 |
Abstract : |
PubMedSearch : Varela-Nallar_2012_Cytoskeleton.(Hoboken)_69_528 |
PubMedID: 22407911 |
Title : Synaptic defects associated with s-inclusion body myositis are prevented by copper - Aldunate_2012_Biometals_25_815 |
Author(s) : Aldunate R , Minniti AN , Rebolledo D , Inestrosa NC |
Ref : Biometals , 25 :815 , 2012 |
Abstract : |
PubMedSearch : Aldunate_2012_Biometals_25_815 |
PubMedID: 22573194 |
Title : The Cellular Prion Protein Prevents Copper-Induced Inhibition of P2X(4) Receptors - Lorca_2011_Int.J.Alzheimers.Dis_2011_706576 |
Author(s) : Lorca RA , Varela-Nallar L , Inestrosa NC , Huidobro-Toro JP |
Ref : Int J Alzheimers Dis , 2011 :706576 , 2011 |
Abstract : |
PubMedSearch : Lorca_2011_Int.J.Alzheimers.Dis_2011_706576 |
PubMedID: 22114745 |
Title : Copper reduces Abeta oligomeric species and ameliorates neuromuscular synaptic defects in a C. elegans model of inclusion body myositis - Rebolledo_2011_J.Neurosci_31_10149 |
Author(s) : Rebolledo DL , Aldunate R , Kohn R , Neira I , Minniti AN , Inestrosa NC |
Ref : Journal of Neuroscience , 31 :10149 , 2011 |
Abstract : |
PubMedSearch : Rebolledo_2011_J.Neurosci_31_10149 |
PubMedID: 21752991 |
Title : Tetrahydrohyperforin prevents cognitive deficit, Abeta deposition, tau phosphorylation and synaptotoxicity in the APPswe\/PSEN1DeltaE9 model of Alzheimer's disease: a possible effect on APP processing - Inestrosa_2011_Transl.Psychiatry_1_e20 |
Author(s) : Inestrosa NC , Tapia-Rojas C , Griffith TN , Carvajal FJ , Benito MJ , Rivera-Dictter A , Alvarez AR , Serrano FG , Hancke JL , Burgos PV , Parodi J , Varela-Nallar L |
Ref : Transl Psychiatry , 1 :e20 , 2011 |
Abstract : |
PubMedSearch : Inestrosa_2011_Transl.Psychiatry_1_e20 |
PubMedID: 22832522 |
Title : The synaptic protein neuroligin-1 interacts with the amyloid beta-peptide. Is there a role in Alzheimer's disease? - Dinamarca_2011_Biochemistry_50_8127 |
Author(s) : Dinamarca MC , Weinstein D , Monasterio O , Inestrosa NC |
Ref : Biochemistry , 50 :8127 , 2011 |
Abstract : |
PubMedSearch : Dinamarca_2011_Biochemistry_50_8127 |
PubMedID: 21838267 |
Title : Interactions of AChE with Abeta Aggregates in Alzheimer's Brain: Therapeutic Relevance of IDN 5706 - Carvajal_2011_Front.Mol.Neurosci_4_19 |
Author(s) : Carvajal FJ , Inestrosa NC |
Ref : Front Mol Neurosci , 4 :19 , 2011 |
Abstract : |
PubMedSearch : Carvajal_2011_Front.Mol.Neurosci_4_19 |
PubMedID: 21949501 |
Title : Synaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylation - Perez_2010_J.Neurosci_30_3728 |
Author(s) : Perez de Arce K , Varela-Nallar L , Farias O , Cifuentes A , Bull P , Couch BA , Koleske AJ , Inestrosa NC , Alvarez AR |
Ref : Journal of Neuroscience , 30 :3728 , 2010 |
Abstract : |
PubMedSearch : Perez_2010_J.Neurosci_30_3728 |
PubMedID: 20220006 |
Title : Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses - Varela-Nallar_2010_Proc.Natl.Acad.Sci.U.S.A_107_21164 |
Author(s) : Varela-Nallar L , Alfaro IE , Serrano FG , Parodi J , Inestrosa NC |
Ref : Proc Natl Acad Sci U S A , 107 :21164 , 2010 |
Abstract : |
PubMedSearch : Varela-Nallar_2010_Proc.Natl.Acad.Sci.U.S.A_107_21164 |
PubMedID: 21084636 |
Title : Adult hippocampal neurogenesis in aging and Alzheimer's disease - Varela-Nallar_2010_Birth.Defects.Res.C.Embryo.Today_90_284 |
Author(s) : Varela-Nallar L , Aranguiz FC , Abbott AC , Slater PG , Inestrosa NC |
Ref : Birth Defects Res C Embryo Today , 90 :284 , 2010 |
Abstract : |
PubMedSearch : Varela-Nallar_2010_Birth.Defects.Res.C.Embryo.Today_90_284 |
PubMedID: 21181889 |
Title : Neurobiological effects of Hyperforin and its potential in Alzheimer's disease therapy - Griffith_2010_Curr.Med.Chem_17_391 |
Author(s) : Griffith TN , Varela-Nallar L , Dinamarca MC , Inestrosa NC |
Ref : Curr Med Chem , 17 :391 , 2010 |
Abstract : |
PubMedSearch : Griffith_2010_Curr.Med.Chem_17_391 |
PubMedID: 20015041 |
Title : Wnt signaling modulates pre- and postsynaptic maturation: therapeutic considerations - Farias_2010_Dev.Dyn_239_94 |
Author(s) : Farias GG , Godoy JA , Cerpa W , Varela-Nallar L , Inestrosa NC |
Ref : Developmental Dynamics , 239 :94 , 2010 |
Abstract : |
PubMedSearch : Farias_2010_Dev.Dyn_239_94 |
PubMedID: 19681159 |
Title : Overexpression of amyloid precursor protein increases copper content in HEK293 cells - Suazo_2009_Biochem.Biophys.Res.Commun_382_740 |
Author(s) : Suazo M , Hodar C , Morgan C , Cerpa W , Cambiazo V , Inestrosa NC , Gonzalez M |
Ref : Biochemical & Biophysical Research Communications , 382 :740 , 2009 |
Abstract : |
PubMedSearch : Suazo_2009_Biochem.Biophys.Res.Commun_382_740 |
PubMedID: 19318086 |
Title : The role of Wnt signaling in neuroprotection - Cerpa_2009_Drug.News.Perspect_22_579 |
Author(s) : Cerpa W , Toledo EM , Varela-Nallar L , Inestrosa NC |
Ref : Drug News Perspect , 22 :579 , 2009 |
Abstract : |
PubMedSearch : Cerpa_2009_Drug.News.Perspect_22_579 |
PubMedID: 20140278 |
Title : Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function - Varela-Nallar_2009_Neural.Dev_4_41 |
Author(s) : Varela-Nallar L , Grabowski CP , Alfaro IE , Alvarez AR , Inestrosa NC |
Ref : Neural Dev , 4 :41 , 2009 |
Abstract : |
PubMedSearch : Varela-Nallar_2009_Neural.Dev_4_41 |
PubMedID: 19883499 |
Title : Methionine sulfoxide reductase A expression is regulated by the DAF-16\/FOXO pathway in Caenorhabditis elegans - Minniti_2009_Aging.Cell_8_690 |
Author(s) : Minniti AN , Cataldo R , Trigo C , Vasquez L , Mujica P , Leighton F , Inestrosa NC , Aldunate R |
Ref : Aging Cell , 8 :690 , 2009 |
Abstract : |
PubMedSearch : Minniti_2009_Aging.Cell_8_690 |
PubMedID: 19747232 |
Title : Intracellular amyloid formation in muscle cells of Abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification - Minniti_2009_Mol.Neurodegener_4_2 |
Author(s) : Minniti AN , Rebolledo DL , Grez PM , Fadic R , Aldunate R , Volitakis I , Cherny RA , Opazo C , Masters C , Bush AI , Inestrosa NC |
Ref : Mol Neurodegener , 4 :2 , 2009 |
Abstract : |
PubMedSearch : Minniti_2009_Mol.Neurodegener_4_2 |
PubMedID: 19126228 |
Title : Calcium\/calmodulin-dependent protein kinase type IV is a target gene of the Wnt\/beta-catenin signaling pathway - Arrazola_2009_J.Cell.Physiol_221_658 |
Author(s) : Arrazola MS , Varela-Nallar L , Colombres M , Toledo EM , Cruzat F , Pavez L , Assar R , Aravena A , Gonzalez M , Montecino M , Maass A , Martinez S , Inestrosa NC |
Ref : Journal of Cellular Physiology , 221 :658 , 2009 |
Abstract : |
PubMedSearch : Arrazola_2009_J.Cell.Physiol_221_658 |
PubMedID: 19711354 |
Title : Structure-function implications in Alzheimer's disease: effect of Abeta oligomers at central synapses - Cerpa_2008_Curr.Alzheimer.Res_5_233 |
Author(s) : Cerpa W , Dinamarca MC , Inestrosa NC |
Ref : Curr Alzheimer Res , 5 :233 , 2008 |
Abstract : |
PubMedSearch : Cerpa_2008_Curr.Alzheimer.Res_5_233 |
PubMedID: 18537540 |
Title : Amyloid-cholinesterase interactions. Implications for Alzheimer's disease - Inestrosa_2008_FEBS.J_275_625 |
Author(s) : Inestrosa NC , Dinamarca MC , Alvarez A |
Ref : Febs J , 275 :625 , 2008 |
Abstract : |
PubMedSearch : Inestrosa_2008_FEBS.J_275_625 |
PubMedID: 18205831 |
Title : Frizzled-1 is involved in the neuroprotective effect of Wnt3a against Abeta oligomers - Chacon_2008_J.Cell.Physiol_217_215 |
Author(s) : Chacon MA , Varela-Nallar L , Inestrosa NC |
Ref : Journal of Cellular Physiology , 217 :215 , 2008 |
Abstract : |
PubMedSearch : Chacon_2008_J.Cell.Physiol_217_215 |
PubMedID: 18521822 |
Title : Inclusion body myositis: a view from the Caenorhabditis elegans muscle - Rebolledo_2008_Mol.Neurobiol_38_178 |
Author(s) : Rebolledo DL , Minniti AN , Grez PM , Fadic R , Kohn R , Inestrosa NC |
Ref : Molecular Neurobiology , 38 :178 , 2008 |
Abstract : |
PubMedSearch : Rebolledo_2008_Mol.Neurobiol_38_178 |
PubMedID: 18773311 |
Title : Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice - Dinamarca_2008_Chem.Biol.Interact_175_142 |
Author(s) : Dinamarca MC , Arrazola M , Toledo E , Cerpa WF , Hancke J , Inestrosa NC |
Ref : Chemico-Biological Interactions , 175 :142 , 2008 |
Abstract : |
PubMedSearch : Dinamarca_2008_Chem.Biol.Interact_175_142 |
PubMedID: 18599028 |
Title : Synaptotoxicity in Alzheimer's disease: the Wnt signaling pathway as a molecular target - Inestrosa_2007_IUBMB.Life_59_316 |
Author(s) : Inestrosa NC , Varela-Nallar L , Grabowski CP , Colombres M |
Ref : IUBMB Life , 59 :316 , 2007 |
Abstract : |
PubMedSearch : Inestrosa_2007_IUBMB.Life_59_316 |
PubMedID: 17505971 |
Title : Role of copper in prion diseases: deleterious or beneficial? - Varela-Nallar_2006_Curr.Pharm.Des_12_2587 |
Author(s) : Varela-Nallar L , Gonzalez A , Inestrosa NC |
Ref : Curr Pharm Des , 12 :2587 , 2006 |
Abstract : |
PubMedSearch : Varela-Nallar_2006_Curr.Pharm.Des_12_2587 |
PubMedID: 16842180 |
Title : Localization, specific activity, and molecular forms of acetylcholinesterase in developmental stages of the cestode Mesocestoides corti - Kemmerling_2006_J.Cell.Physiol_206_503 |
Author(s) : Kemmerling U , Cabrera G , Campos EO , Inestrosa NC , Galanti N |
Ref : Journal of Cellular Physiology , 206 :503 , 2006 |
Abstract : |
PubMedSearch : Kemmerling_2006_J.Cell.Physiol_206_503 |
PubMedID: 16155922 |
Title : The functional links between prion protein and copper - Varela-Nallar_2006_Biol.Res_39_39 |
Author(s) : Varela-Nallar L , Toledo EM , Chacon MA , Inestrosa NC |
Ref : Biol Res , 39 :39 , 2006 |
Abstract : |
PubMedSearch : Varela-Nallar_2006_Biol.Res_39_39 |
PubMedID: 16629163 |
Title : Induction of cellular prion protein gene expression by copper in neurons - Varela-Nallar_2006_Am.J.Physiol.Cell.Physiol_290_C271 |
Author(s) : Varela-Nallar L , Toledo EM , Larrondo LF , Cabral AL , Martins VR , Inestrosa NC |
Ref : American Journal of Physiology Cell Physiol , 290 :C271 , 2006 |
Abstract : |
PubMedSearch : Varela-Nallar_2006_Am.J.Physiol.Cell.Physiol_290_C271 |
PubMedID: 16148034 |
Title : Is there a role for copper in neurodegenerative diseases? - Cerpa_2005_Mol.Aspects.Med_26_405 |
Author(s) : Cerpa W , Varela-Nallar L , Reyes AE , Minniti AN , Inestrosa NC |
Ref : Mol Aspects Med , 26 :405 , 2005 |
Abstract : |
PubMedSearch : Cerpa_2005_Mol.Aspects.Med_26_405 |
PubMedID: 16112188 |
Title : Blood cells cholinesterase activity in early stage Alzheimer's disease and vascular dementia - von Bernhardi_2005_Dement.Geriatr.Cogn.Disord_19_204 |
Author(s) : Von Bernhardi R , Alarcon R , Mezzano D , Fuentes P , Inestrosa NC |
Ref : Dementia & Geriatric Cognitive Disorders , 19 :204 , 2005 |
Abstract : |
PubMedSearch : von Bernhardi_2005_Dement.Geriatr.Cogn.Disord_19_204 |
PubMedID: 15677868 |
Title : Copper brain homeostasis: role of amyloid precursor protein and prion protein - Inestrosa_2005_IUBMB.Life_57_645 |
Author(s) : Inestrosa NC , Cerpa W , Varela-Nallar L |
Ref : IUBMB Life , 57 :645 , 2005 |
Abstract : |
PubMedSearch : Inestrosa_2005_IUBMB.Life_57_645 |
PubMedID: 16203684 |
Title : Acetylcholinesterase-amyloid-beta-peptide interaction: effect of Congo Red and the role of the Wnt pathway - Inestrosa_2005_Curr.Alzheimer.Res_2_301 |
Author(s) : Inestrosa NC , Alvarez A , Dinamarca MC , Perez-Acle T , Colombres M |
Ref : Curr Alzheimer Res , 2 :301 , 2005 |
Abstract : |
PubMedSearch : Inestrosa_2005_Curr.Alzheimer.Res_2_301 |
PubMedID: 15974895 |
Title : Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu - Inestrosa_2005_Neurobiol.Aging_26_1023 |
Author(s) : Inestrosa NC , Reyes AE , Chacon MA , Cerpa W , Villalon A , Montiel J , Merabachvili G , Aldunate R , Bozinovic F , Aboitiz F |
Ref : Neurobiology of Aging , 26 :1023 , 2005 |
Abstract : |
PubMedSearch : Inestrosa_2005_Neurobiol.Aging_26_1023 |
PubMedID: 15748782 |
Title : Acetylcholinesterase interaction with Alzheimer amyloid beta - Inestrosa_2005_Subcell.Biochem_38_299 |
Author(s) : Inestrosa NC , Sagal JP , Colombres M |
Ref : Subcell Biochem , 38 :299 , 2005 |
Abstract : |
PubMedSearch : Inestrosa_2005_Subcell.Biochem_38_299 |
PubMedID: 15709485 |
Title : The anti-inflammatory and cholinesterase inhibitor bifunctional compound IBU-PO protects from beta-amyloid neurotoxicity by acting on Wnt signaling components - Farias_2005_Neurobiol.Dis_18_176 |
Author(s) : Farias GG , Godoy JA , Vazquez MC , Adani R , Meshulam H , Avila J , Amitai G , Inestrosa NC |
Ref : Neurobiol Dis , 18 :176 , 2005 |
Abstract : |
PubMedSearch : Farias_2005_Neurobiol.Dis_18_176 |
PubMedID: 15649708 |
Title : Nerve-induced muscle activity modulates CGRP effect on AChE expression in rat myotubes - |
Author(s) : Aldunate R , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :31 , 2004 |
PubMedID: |
Title : Poster (80) The anti-inflammatory-cholinergic bifunctional compound ibu-po protects at sub-micromolar levels rat hippocampal cells from a beta-induced apoptosis and beta-catenin depletion - |
Author(s) : Godoy JA , Adani R , Meshulam H , Inestrosa NC , Amitai G |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :363 , 2004 |
PubMedID: |
Title : Poster (77) Galanthamine inhibits the aggregation of the amyloid-beta-peptide stimulated by acetylcholinesterase in vitro. - |
Author(s) : Dinamarca MC , Campos EO , Hancke JL , Rakonczay Z , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :361 , 2004 |
PubMedID: |
Title : Neurodegenerative processes in Alzheimer's disease: Role of A-beta-AChE complexes and Wnt signaling - |
Author(s) : Inestrosa NC , Colombres M , De Ferrari GV |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :95 , 2004 |
PubMedID: |
Title : Poster (92) Acetylcholinesterase stabilizes amyloid fibrils against disassembly induced by laminin - |
Author(s) : Morgan C , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :369 , 2004 |
PubMedID: |
Title : Effects of intrahippocampal injection of acetylcholinesterase-A-beta complexes and AChE alone: Analysis of neuropathological changes and spatial learning acquisition - |
Author(s) : Chacon MA , Reyes AE , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :119 , 2004 |
PubMedID: |
Title : The anti-inflammatory bifunctional compound IBU-PO protects rat hippocampal neurons from A-beta-induced cytotoxicity and beta-catenin depletion - |
Author(s) : Godoy JA , Adani R , Meshulam H , Inestrosa NC , Amitai G |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :135 , 2004 |
PubMedID: |
Title : Signal transduction during amyloid-beta-peptide neurotoxicity: role in Alzheimer disease - Fuentealba_2004_Brain.Res.Brain.Res.Rev_47_275 |
Author(s) : Fuentealba RA , Farias G , Scheu J , Bronfman M , Marzolo MP , Inestrosa NC |
Ref : Brain Research Brain Res Rev , 47 :275 , 2004 |
Abstract : |
PubMedSearch : Fuentealba_2004_Brain.Res.Brain.Res.Rev_47_275 |
PubMedID: 15572177 |
Title : Acetylcholinesterase stabilizes beta-amyloid fibrils against disassembly induced by laminin - |
Author(s) : Morgan C , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :141 , 2004 |
PubMedID: |
Title : The association of AChE to A-beta peptide aggregates increases its neurotoxicity - |
Author(s) : Alvarez A , Godoy JA , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :147 , 2004 |
PubMedID: |
Title : Increased detection of amyloid precursor protein in astrocytes exposed to acetylcholinesterase in culture - |
Author(s) : Von Bernhardi R , Ramirez G , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :153 , 2004 |
PubMedID: |
Title : Decreased cholinesterase activity in blood cells of Alzheimer's disease patients - |
Author(s) : Von Bernhardi R , Alarcon R , Mezzano D , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :159 , 2004 |
PubMedID: |
Title : Poster (102) Blood cells cholinesterase activity and dementia: decreased activity is established from early stages in alzheimer's disease and is common to various organic dementias - |
Author(s) : Von Bernhardi R , Alarcon R , Mezzano D , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :373 , 2004 |
PubMedID: |
Title : Poster (103) Acetylcholinesterase induces the expression of the beta-amyloid precursor protein in astrocytes and activates glial cells in culture - |
Author(s) : Von Bernhardi R , Ramirez G , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :374 , 2004 |
PubMedID: |
Title : Stepwise construction of triple-helical heparin binding sites using peptide models - Doss-Pepe_2004_Biochim.Biophys.Acta_1698_187 |
Author(s) : Doss-Pepe E , Deprez P , Silva T , Inestrosa NC , Kirkpatrick A , Ramshaw JA , Brodsky B |
Ref : Biochimica & Biophysica Acta , 1698 :187 , 2004 |
Abstract : |
PubMedSearch : Doss-Pepe_2004_Biochim.Biophys.Acta_1698_187 |
PubMedID: 15134651 |
Title : Structural and functional organization of synaptic acetylcholinesterase - Aldunate_2004_Brain.Res.Brain.Res.Rev_47_96 |
Author(s) : Aldunate R , Casar JC , Brandan E , Inestrosa NC |
Ref : Brain Research Brain Res Rev , 47 :96 , 2004 |
Abstract : |
PubMedSearch : Aldunate_2004_Brain.Res.Brain.Res.Rev_47_96 |
PubMedID: 15572165 |
Title : Poster (40) Acetylcholinesterase - amyloid beta-peptide interaction. - |
Author(s) : De Ferrari GV , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :342 , 2004 |
PubMedID: |
Title : Acetylcholinesterase-Abeta complexes are more toxic than Abeta fibrils in rat hippocampus: effect on rat beta-amyloid aggregation, laminin expression, reactive astrocytosis, and neuronal cell loss - Reyes_2004_Am.J.Pathol_164_2163 |
Author(s) : Reyes AE , Chacon MA , Dinamarca MC , Cerpa W , Morgan C , Inestrosa NC |
Ref : American Journal of Pathology , 164 :2163 , 2004 |
Abstract : |
PubMedSearch : Reyes_2004_Am.J.Pathol_164_2163 |
PubMedID: 15161650 |
Title : Structure and function of amyloid in Alzheimer's disease - Morgan_2004_Prog.Neurobiol_74_323 |
Author(s) : Morgan C , Colombres M , Nunez MT , Inestrosa NC |
Ref : Prog Neurobiol , 74 :323 , 2004 |
Abstract : |
PubMedSearch : Morgan_2004_Prog.Neurobiol_74_323 |
PubMedID: 15649580 |
Title : An overview of the current and novel drugs for Alzheimer's disease with particular reference to anti-cholinesterase compounds - Colombres_2004_Curr.Pharm.Des_10_3121 |
Author(s) : Colombres M , Sagal JP , Inestrosa NC |
Ref : Curr Pharm Des , 10 :3121 , 2004 |
Abstract : |
PubMedSearch : Colombres_2004_Curr.Pharm.Des_10_3121 |
PubMedID: 15544502 |
Title : Neurodegenerative processes in Alzheimer?s disease. - |
Author(s) : Inestrosa NC , De Ferrari GV , Opazo C , Alvarez A |
Ref : Cholinergic Mechanisms, CRC Press :363 , 2004 |
PubMedID: |
Title : Acetylcholinesterase (AChE)--amyloid-beta-peptide complexes in Alzheimer's disease. the Wnt signaling pathway - Inestrosa_2004_Curr.Alzheimer.Res_1_249 |
Author(s) : Inestrosa NC , Urra S , Colombres M |
Ref : Curr Alzheimer Res , 1 :249 , 2004 |
Abstract : |
PubMedSearch : Inestrosa_2004_Curr.Alzheimer.Res_1_249 |
PubMedID: 15975054 |
Title : Poster (61) Nerve-induced muscle activity modulates cgrp effect on AChE expression in rat myotubes - |
Author(s) : Aldunate R , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :353 , 2004 |
PubMedID: |
Title : Poster (63) The association of acetylcholinesterase to amyloid-beta-peptide aggregates increases jt~ neurotoxicity - |
Author(s) : Alvarez A , Godoy JA , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :354 , 2004 |
PubMedID: |
Title : Poster (71) Acetylcholinesterase induces neuronal loss and spatial memory deficits in mammalian hippocampus - |
Author(s) : Chacon MA , Reyes AE , Calderon R , Alvarez A , Inestrosa NC |
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :357 , 2004 |
PubMedID: |
Title : Two different heparin-binding domains in the triple-helical domain of ColQ, the collagen tail subunit of synaptic acetylcholinesterase - Deprez_2003_J.Biol.Chem_278_23233 |
Author(s) : Deprez P , Inestrosa NC , Krejci E |
Ref : Journal of Biological Chemistry , 278 :23233 , 2003 |
Abstract : |
PubMedSearch : Deprez_2003_J.Biol.Chem_278_23233 |
PubMedID: 12684510 |
Title : Acetylcholinesterase induces neuronal cell loss, astrocyte hypertrophy and behavioral deficits in mammalian hippocampus - Chacon_2003_J.Neurochem_87_195 |
Author(s) : Chacon MA , Reyes AE , Inestrosa NC |
Ref : Journal of Neurochemistry , 87 :195 , 2003 |
Abstract : |
PubMedSearch : Chacon_2003_J.Neurochem_87_195 |
PubMedID: 12969266 |
Title : Acetylcholinesterase induces the expression of the beta-amyloid precursor protein in glia and activates glial cells in culture - von Bernhardi_2003_Neurobiol.Dis_14_447 |
Author(s) : Von Bernhardi R , Ramirez G , De Ferrari GV , Inestrosa NC |
Ref : Neurobiol Dis , 14 :447 , 2003 |
Abstract : |
PubMedSearch : von Bernhardi_2003_Neurobiol.Dis_14_447 |
PubMedID: 14678761 |
Title : Vitamin E but not 17beta-estradiol protects against vascular toxicity induced by beta-amyloid wild type and the Dutch amyloid variant - Munoz_2002_J.Neurosci_22_3081 |
Author(s) : Munoz FJ , Opazo C , Gil-Gomez G , Tapia G , Fernandez V , Valverde MA , Inestrosa NC |
Ref : Journal of Neuroscience , 22 :3081 , 2002 |
Abstract : |
PubMedSearch : Munoz_2002_J.Neurosci_22_3081 |
PubMedID: 11943811 |
Title : Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and the acylation sites - De Ferrari_2001_J.Biol.Chem_276_23282 |
Author(s) : De Ferrari GV , Mallender WD , Inestrosa NC , Rosenberry TL |
Ref : Journal of Biological Chemistry , 276 :23282 , 2001 |
Abstract : |
PubMedSearch : De Ferrari_2001_J.Biol.Chem_276_23282 |
PubMedID: 11313335 |
Title : A Structural Motif of Acetylcholinesterase That Promotes Amyloid beta-Peptide Fibril Formation - De Ferrari_2001_Biochemistry_40_10447 |
Author(s) : De Ferrari GV , Canales MA , Shin I , Weiner L , Silman I , Inestrosa NC |
Ref : Biochemistry , 40 :10447 , 2001 |
Abstract : |
PubMedSearch : De Ferrari_2001_Biochemistry_40_10447 |
PubMedID: 11523986 |
Title : Interaction of collagen-like peptide models of asymmetric acetylcholinesterase with glycosaminoglycans: spectroscopic studies of conformational changes and stability - Doss-Pepe_2000_Biochemistry_39_14884 |
Author(s) : Doss-Pepe E , Deprez P , Inestrosa NC , Brodsky B |
Ref : Biochemistry , 39 :14884 , 2000 |
Abstract : |
PubMedSearch : Doss-Pepe_2000_Biochemistry_39_14884 |
PubMedID: 11101304 |
Title : Interaction of the collagen-like tail of asymmetric acetylcholinesterase with heparin depends on triple-helical conformation, sequence and stability - Deprez_2000_Biochem.J_350 Pt 1_283 |
Author(s) : Deprez P , Doss-Pepe E , Brodsky B , Inestrosa NC |
Ref : Biochemical Journal , 350 Pt 1 :283 , 2000 |
Abstract : |
PubMedSearch : Deprez_2000_Biochem.J_350 Pt 1_283 |
PubMedID: 10926855 |
Title : Acetylcholinesterase-amyloid-beta-peptide interaction and Wnt signaling involvement in Abeta neurotoxicity - Inestrosa_2000_Acta.Neurol.Scand.Suppl_176_53 |
Author(s) : Inestrosa NC , Alvarez A , Godoy J , Reyes A , De Ferrari GV |
Ref : Acta Neurologica Scandinavica Supplementum , 176 :53 , 2000 |
Abstract : |
PubMedSearch : Inestrosa_2000_Acta.Neurol.Scand.Suppl_176_53 |
PubMedID: 11261806 |
Title : The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease - Miranda_2000_Prog.Neurobiol_62_633 |
Author(s) : Miranda S , Opazo C , Larrondo LF , Munoz FJ , Ruiz F , Leighton F , Inestrosa NC |
Ref : Prog Neurobiol , 62 :633 , 2000 |
Abstract : |
PubMedSearch : Miranda_2000_Prog.Neurobiol_62_633 |
PubMedID: 10880853 |
Title : Molecular modeling of the collagen-like tail of asymmetric acetylcholinesterase - Deprez_2000_Protein.Eng_13_27 |
Author(s) : Deprez P , Inestrosa NC |
Ref : Protein Engineering , 13 :27 , 2000 |
Abstract : |
PubMedSearch : Deprez_2000_Protein.Eng_13_27 |
PubMedID: 10679527 |
Title : PC12 and neuro 2a cells have different susceptibilities to acetylcholinesterase-amyloid complexes, amyloid25-35 fragment, glutamate, and hydrogen peroxide - Calderon_1999_J.Neurosci.Res_56_620 |
Author(s) : Calderon FH , Bonnefont A , Munoz FJ , Fernandez V , Videla LA , Inestrosa NC |
Ref : Journal of Neuroscience Research , 56 :620 , 1999 |
Abstract : |
PubMedSearch : Calderon_1999_J.Neurosci.Res_56_620 |
PubMedID: 10374817 |
Title : Mannose receptor is present in a functional state in rat microglial cells - Marzolo_1999_J.Neurosci.Res_58_387 |
Author(s) : Marzolo MP , Von Bernhardi R , Inestrosa NC |
Ref : Journal of Neuroscience Research , 58 :387 , 1999 |
Abstract : |
PubMedSearch : Marzolo_1999_J.Neurosci.Res_58_387 |
PubMedID: 10518112 |
Title : Peripheral binding site is involved in the neurotrophic activity of acetylcholinesterase - Munoz_1999_Neuroreport_10_3621 |
Author(s) : Munoz FJ , Aldunate R , Inestrosa NC |
Ref : Neuroreport , 10 :3621 , 1999 |
Abstract : |
PubMedSearch : Munoz_1999_Neuroreport_10_3621 |
PubMedID: 10619655 |
Title : Neurotoxicity of acetylcholinesterase amyloid beta-peptide aggregates is dependent on the type of Abeta peptide and the AChE concentration present in the complexes - Munoz_1999_FEBS.Lett_450_205 |
Author(s) : Munoz FJ , Inestrosa NC |
Ref : FEBS Letters , 450 :205 , 1999 |
Abstract : |
PubMedSearch : Munoz_1999_FEBS.Lett_450_205 |
PubMedID: 10359075 |
Title : The Heparin-Binding Sites in the Collagenic Tail of Acetylcholinesterase - 1 - |
Author(s) : Deprez P , Inestrosa NC |
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :444 , 1998 |
PubMedID: |
Title : The Heparin-Binding Sites in the Collagenic Tail of Acetylcholinesterase - 2 - |
Author(s) : Deprez P , Krejci E , Inestrosa NC , Massoulie J |
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :446 , 1998 |
PubMedID: |
Title : Laminin blocks the assembly of wild-type A beta and the Dutch variant peptide into Alzheimer's fibrils - Bronfman_1998_Amyloid_5_16 |
Author(s) : Bronfman FC , Alvarez A , Morgan C , Inestrosa NC |
Ref : Amyloid , 5 :16 , 1998 |
Abstract : |
PubMedSearch : Bronfman_1998_Amyloid_5_16 |
PubMedID: 9547001 |
Title : Toxic effects of acetylcholinesterase on neuronal and glial-like cells in vitro - Calderon_1998_Mol.Psychiatry_3_247 |
Author(s) : Calderon FH , Von Bernhardi R , De Ferrari GV , Luza S , Aldunate R , Inestrosa NC |
Ref : Mol Psychiatry , 3 :247 , 1998 |
Abstract : |
PubMedSearch : Calderon_1998_Mol.Psychiatry_3_247 |
PubMedID: 9672900 |
Title : Molecular Interactions of Acetylcholinesterase with the Synaptic Basal Lamina and the Senile Plaques - |
Author(s) : Inestrosa NC , Alarcon R , Alvarez A , Calderon FH , Campos EO , Casanueva OI , De Ferrari GV , Deprez P , Garcia-Huidobro T , Munoz FJ , Perez D , Reyes AE |
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :167 , 1998 |
PubMedID: |
Title : At least two receptors of asymmetric acetylcholinesterase are present at the synaptic basal lamina of Torpedo electric organ - Casanueva_1998_Biochem.Biophys.Res.Commun_250_312 |
Author(s) : Casanueva OI , Deprez P , Garcia-Huidobro T , Inestrosa NC |
Ref : Biochemical & Biophysical Research Communications , 250 :312 , 1998 |
Abstract : |
PubMedSearch : Casanueva_1998_Biochem.Biophys.Res.Commun_250_312 |
PubMedID: 9753626 |
Title : Acetylcholinesterase Enhances the Neurotoxicity of beta-Amyloid Fibrils - |
Author(s) : Munoz FJ , Inestrosa NC |
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :182 , 1998 |
PubMedID: |
Title : Identification of an Acetylcholinesterase Fragment that Promotes Alzheimer beta-Amyloid Fibril Formation - |
Author(s) : De Ferrari GV , Inestrosa NC |
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :185 , 1998 |
PubMedID: |
Title : Differential Effect of Acetylcholinesterase on Neuronal and Glial Cells in Culture - |
Author(s) : Calderon FH , Inestrosa NC |
Ref : In: Structure and Function of Cholinesterases and Related Proteins - Proceedings of Sixth International Meeting on Cholinesterases , (Doctor, B.P., Taylor, P., Quinn, D.M., Rotundo, R.L., Gentry, M.K. Eds) Plenum Publishing Corp. :187 , 1998 |
PubMedID: |
Title : Dissection of the heparin-binding domains present in the collagenic tail of mammalian acetylcholinesterase - |
Author(s) : Deprez P , Krejci E , Massoulie J , Inestrosa NC |
Ref : Journal de Physiologie (Paris) , 92 :425 , 1998 |
PubMedID: |
Title : Crosslinking of amyloid-beta peptide to brain acetylcholinesterase - Opazo_1998_Mol.Chem.Neuropathol_33_39 |
Author(s) : Opazo C , Inestrosa NC |
Ref : Molecular & Chemical Neuropathology , 33 :39 , 1998 |
Abstract : |
PubMedSearch : Opazo_1998_Mol.Chem.Neuropathol_33_39 |
PubMedID: 9493175 |
Title : A major portion of synaptic basal lamina acetylcholinesterase is detached by high salt- and heparin-containing buffers from rat diaphragm muscle and torpedo electric organ - Casanueva_1998_J.Biol.Chem_273_4258 |
Author(s) : Casanueva OI , Garcia-Huidobro T , Campos EO , Aldunate R , Garrido J , Inestrosa NC |
Ref : Journal of Biological Chemistry , 273 :4258 , 1998 |
Abstract : |
PubMedSearch : Casanueva_1998_J.Biol.Chem_273_4258 |
PubMedID: 9461624 |
Title : Brain acetylcholinesterase promotes amyloid-beta-peptide aggregation but does not hydrolyze amyloid precursor protein peptides - Campos_1998_Neurochem.Res_23_135 |
Author(s) : Campos EO , Alvarez A , Inestrosa NC |
Ref : Neurochem Res , 23 :135 , 1998 |
Abstract : |
PubMedSearch : Campos_1998_Neurochem.Res_23_135 |
PubMedID: 9475506 |
Title : Responses induced by tacrine in neuronal and non-neuronal cell lines - De Ferrari_1998_J.Neurosci.Res_52_435 |
Author(s) : De Ferrari GV , Von Bernhardi R , Calderon FH , Luza SC , Inestrosa NC |
Ref : Journal of Neuroscience Research , 52 :435 , 1998 |
Abstract : |
PubMedSearch : De Ferrari_1998_J.Neurosci.Res_52_435 |
PubMedID: 9589388 |
Title : Molecular interactions of acetylcholinesterase with senile plaques - Inestrosa_1998_J.Physiol.Paris_92_341 |
Author(s) : Inestrosa NC , Alarcon R |
Ref : Journal de Physiologie (Paris) , 92 :341 , 1998 |
Abstract : |
PubMedSearch : Inestrosa_1998_J.Physiol.Paris_92_341 |
PubMedID: 9789834 |
Title : Stable Complexes Involving Acetylcholinesterase and Amyloid-beta Peptide Change the Biochemical Properties of the Enzyme and Increase the Neurotoxicity of Alzheimer's Fibrils - Alvarez_1998_J.Neurosci_18_3213 |
Author(s) : Alvarez A , Alarcon R , Opazo C , Campos EO , Munoz FJ , Calderon FH , Dajas F , Gentry MK , Doctor BP , de Mello FG , Inestrosa NC |
Ref : Journal of Neuroscience , 18 :3213 , 1998 |
Abstract : |
PubMedSearch : Alvarez_1998_J.Neurosci_18_3213 |
PubMedID: 9547230 |
Title : Developmental regulation of mouse brain monomeric acetylcholinesterase - Moreno_1998_Int.J.Dev.Neurosci_16_123 |
Author(s) : Moreno RD , Campos FO , Dajas F , Inestrosa NC |
Ref : Int J Developmental Neuroscience , 16 :123 , 1998 |
Abstract : |
PubMedSearch : Moreno_1998_Int.J.Dev.Neurosci_16_123 |
PubMedID: 9762585 |
Title : Kinetic and thermodynamic effects of acetylcholinesterase on the solubility of Abeta peptide - |
Author(s) : Perez D , Alarcon R , Inestrosa NC |
Ref : Journal de Physiologie (Paris) , 92 :479 , 1998 |
PubMedID: |
Title : Estrogen protects neuronal cells from the cytotoxicity induced by acetylcholinesterase-amyloid complexes - Bonnefont_1998_FEBS.Lett_441_220 |
Author(s) : Bonnefont AB , Munoz FJ , Inestrosa NC |
Ref : FEBS Letters , 441 :220 , 1998 |
Abstract : |
PubMedSearch : Bonnefont_1998_FEBS.Lett_441_220 |
PubMedID: 9883888 |
Title : A monoclonal antibody against acetylcholinesterase inhibits the formation of amyloid fibrils induced by the enzyme - Reyes_1997_Biochem.Biophys.Res.Commun_232_652 |
Author(s) : Reyes AE , Perez DR , Alvarez A , Garrido J , Gentry MK , Doctor BP , Inestrosa NC |
Ref : Biochemical & Biophysical Research Communications , 232 :652 , 1997 |
Abstract : |
PubMedSearch : Reyes_1997_Biochem.Biophys.Res.Commun_232_652 |
PubMedID: 9126330 |
Title : Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils - Alvarez_1997_J.Mol.Biol_272_348 |
Author(s) : Alvarez A , Opazo C , Alarcon R , Garrido J , Inestrosa NC |
Ref : Journal of Molecular Biology , 272 :348 , 1997 |
Abstract : |
PubMedSearch : Alvarez_1997_J.Mol.Biol_272_348 |
PubMedID: 9325095 |
Title : Amyloid precursor protein fragment and acetylcholinesterase increase with cell confluence and differentiation in a neuronal cell line - Bronfman_1996_Exp.Cell.Res_229_93 |
Author(s) : Bronfman FC , Fernandez HL , Inestrosa NC |
Ref : Experimental Cell Research , 229 :93 , 1996 |
Abstract : |
PubMedSearch : Bronfman_1996_Exp.Cell.Res_229_93 |
PubMedID: 8940253 |
Title : Tetrameric (G4) acetylcholinesterase: structure, localization, and physiological regulation. - Fernandez_1996_J.Neurochem_66_1335 |
Author(s) : Fernandez HL , Moreno RD , Inestrosa NC |
Ref : Journal of Neurochemistry , 66 :1335 , 1996 |
Abstract : |
PubMedSearch : Fernandez_1996_J.Neurochem_66_1335 |
PubMedID: 8627284 |
Title : Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme - Inestrosa_1996_Neuron_16_881 |
Author(s) : Inestrosa NC , Alvarez A , Perez CA , Moreno RD , Vicente M , Linker C , Casanueva OI , Soto C , Garrido J |
Ref : Neuron , 16 :881 , 1996 |
Abstract : |
PubMedSearch : Inestrosa_1996_Neuron_16_881 |
PubMedID: 8608006 |
Title : Acetylcholinesterase, a senile plaque component, affects the fibrillogenesis of amyloid-beta-peptides - Alvarez_1995_Neurosci.Lett_201_49 |
Author(s) : Alvarez A , Bronfman F , Perez CA , Vicente M , Garrido J , Inestrosa NC |
Ref : Neuroscience Letters , 201 :49 , 1995 |
Abstract : |
PubMedSearch : Alvarez_1995_Neurosci.Lett_201_49 |
PubMedID: 96274631 |
Title : Two heparin-binding domains are present on the collagenic tail of asymmetric acetylcholinesterase - Deprez_1995_J.Biol.Chem_270_11043 |
Author(s) : Deprez P , Inestrosa NC |
Ref : Journal of Biological Chemistry , 270 :11043 , 1995 |
Abstract : |
PubMedSearch : Deprez_1995_J.Biol.Chem_270_11043 |
PubMedID: 7744733 |
Title : Effect of protamine on the solubilization of collagen-tailed acetylcholinesterase: potential heparin-binding consensus sequences in the tail of the enzyme - Deprez_1995_Biochim.Biophys.Acta_1252_53 |
Author(s) : Deprez P , Signorelli J , Inestrosa NC |
Ref : Biochimica & Biophysica Acta , 1252 :53 , 1995 |
Abstract : |
PubMedSearch : Deprez_1995_Biochim.Biophys.Acta_1252_53 |
PubMedID: 7548166 |
Title : Blood markers in Alzheimer disease: subnormal acetylcholinesterase and butyrylcholinesterase in lymphocytes and erythrocytes - Inestrosa_1994_J.Neurol.Sci_122_1 |
Author(s) : Inestrosa NC , Alarcon R , Arriagada J , Donoso A , Alvarez J , Campos EO |
Ref : Journal of the Neurological Sciences , 122 :1 , 1994 |
Abstract : |
PubMedSearch : Inestrosa_1994_J.Neurol.Sci_122_1 |
PubMedID: 8195795 |
Title : Monomeric amphiphilic forms of acetylcholinesterase appear early during brain development and may correspond to biosynthetic precursors of the amphiphilic G4 forms - Inestrosa_1994_Neurosci.Lett_173_155 |
Author(s) : Inestrosa NC , Moreno RD , Fuentes ME |
Ref : Neuroscience Letters , 173 :155 , 1994 |
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PubMedSearch : Inestrosa_1994_Neurosci.Lett_173_155 |
PubMedID: 7936404 |
Title : Sensitivity of acetylcholinesterase molecular forms to inhibition by high MgCl2 concentration - Inestrosa_1994_Biochim.Biophys.Acta_1208_286 |
Author(s) : Inestrosa NC , Perez CA , Simpfendorfer RW |
Ref : Biochimica & Biophysica Acta , 1208 :286 , 1994 |
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PubMedSearch : Inestrosa_1994_Biochim.Biophys.Acta_1208_286 |
PubMedID: 7947960 |
Title : Acetylcholinesterase changes in hearts with sinus rhythm and atrial fibrillation - Gonzalez_1993_Gen.Pharmacol_24_111 |
Author(s) : Gonzalez RA , Campos EO , Karmelic C , Moran S , Inestrosa NC |
Ref : General Pharmacology , 24 :111 , 1993 |
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PubMedSearch : Gonzalez_1993_Gen.Pharmacol_24_111 |
PubMedID: 8482484 |
Title : Binding of Asymmetric (Al2) Acetylcholinesterase to C2 Muscle Cells and to Cho Mutants Defective in Glycosaminoglycan Synthesis - |
Author(s) : Inestrosa NC , Gordon H |
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PubMedID: |
Title : Amphiphilic behavior of a brain tetrameric acetylcholinesterase form lacking the plasma membrane anchoring domain - Fuentes_1992_Brain.Res_580_1 |
Author(s) : Fuentes ME , Inestrosa NC |
Ref : Brain Research , 580 :1 , 1992 |
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PubMedSearch : Fuentes_1992_Brain.Res_580_1 |
PubMedID: 1504788 |
Title : Characterization of acetylcholinesterase from human heart auricles: evidence for the presence of a G-form sensitive to phosphatidylinositol-specific phospholipase c - Gonzalez_1991_Gen.Pharmacol_22_107 |
Author(s) : Gonzalez R , Campos EO , Moran S , Inestrosa NC |
Ref : General Pharmacology , 22 :107 , 1991 |
Abstract : |
PubMedSearch : Gonzalez_1991_Gen.Pharmacol_22_107 |
PubMedID: 1646743 |
Title : A comparison of the Xenopus laevis oocyte acetylcholinesterase with the muscle and brain enzyme suggests variations at the post-translational level - Moya_1991_Comp.Biochem.Physiol.C_98_299 |
Author(s) : Moya MA , Fuentes ME , Inestrosa NC |
Ref : Comparative Biochemistry & Physiology C Pharmacol Toxicol , 98 :299 , 1991 |
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PubMedID: 1676945 |
Title : Differential association and distribution of acetyl- and butyrylcholinesterases within rat liver subcellular organelles - Perelman_1990_J.Biol.Chem_265_214 |
Author(s) : Perelman A , Abeijon C , Hirschberg CB , Inestrosa NC , Brandan E |
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PubMedID: 2152920 |
Title : [Biotechnological aspects in loco larvae]. [Spanish] - Inestrosa_1990_Arch.Biol.Med.Exp_23_179 |
Author(s) : Inestrosa NC , Labarca R , Perelman A , Campos EO , Araneda R , Gonzalez M , Brandan E , Sanchez JP , Gonzalez-Plaza R |
Ref : Archivos de Biologia y Medicina Experimentales , 23 :179 , 1990 |
Abstract : |
PubMedSearch : Inestrosa_1990_Arch.Biol.Med.Exp_23_179 |
PubMedID: 1966831 |
Title : Motor nerve regulates muscle extracellular matrix proteoglycan expression - Fadic_1990_J.Neurosci_10_3516 |
Author(s) : Fadic R , Brandan E , Inestrosa NC |
Ref : Journal of Neuroscience , 10 :3516 , 1990 |
Abstract : |
PubMedSearch : Fadic_1990_J.Neurosci_10_3516 |
PubMedID: 2230941 |
Title : Dermatan sulfate and de-sulfated heparin solubilized collagen-tailed acetylcholinesterase from the rat neuromuscular junction - von Bernhardi_1990_Brain.Res_529_91 |
Author(s) : Von Bernhardi R , Inestrosa NC |
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Abstract : |
PubMedSearch : von Bernhardi_1990_Brain.Res_529_91 |
PubMedID: 2282507 |
Title : Carrageenans solubilize asymmetric acetylcholinesterase from nicotinic cholinergic synapses - von Bernhardi_1990_Comp.Biochem.Physiol.C_96_77 |
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Abstract : |
PubMedSearch : von Bernhardi_1990_Comp.Biochem.Physiol.C_96_77 |
PubMedID: 1980885 |
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Author(s) : Inestrosa NC , Perelman A |
Ref : Journal of Membrane Biology , 118 :1 , 1990 |
PubMedID: 2283677 |
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Author(s) : Perelman A , Inestrosa NC |
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Abstract : |
PubMedSearch : Perelman_1989_Anal.Biochem_180_227 |
PubMedID: 2817352 |
Title : Phosphatidylinositol-specific phospholipase C solubilized G2 acetylcholinesterase from plasma membranes of chromaffin cells - Prieto_1989_J.Neurosci.Res_24_169 |
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Title : Distribution and anchoring of molecular forms of acetylcholinesterase. - Inestrosa_1989_TIPS_10_325 |
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PubMedID: 2686130 |
Title : Nerve regulation of class I and class II-asymmetric forms of acetylcholinesterase in rat skeletal muscles - Fadic_1989_J.Neurosci.Res_22_449 |
Author(s) : Fadic R , Inestrosa NC |
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Abstract : |
PubMedSearch : Fadic_1989_J.Neurosci.Res_22_449 |
PubMedID: 2760943 |
Title : A membrane-associated dimer of acetylcholinesterase from Xenopus skeletal muscle is solubilized by phosphatidylinositol-specific phospholipase C - Inestrosa_1988_Neurosci.Lett_90_186 |
Author(s) : Inestrosa NC , Fuentes ME , Anglister L , Futerman AH , Silman I |
Ref : Neuroscience Letters , 90 :186 , 1988 |
Abstract : |
PubMedSearch : Inestrosa_1988_Neurosci.Lett_90_186 |
PubMedID: 3412641 |
Title : Changes in contralateral synaptic acetylcholinesterase following motor nerve section in rats - Fadic_1988_Neurosci.Lett_90_229 |
Author(s) : Fadic R , Soza MA , Inestrosa NC |
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PubMedSearch : Fadic_1988_Neurosci.Lett_90_229 |
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Title : Characterization of a tetrameric G4 form of acetylcholinesterase from bovine brain: a comparison with the dimeric G2 form of the electric organ - Fuentes_1988_Mol.Cell.Biochem_81_53 |
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PubMedSearch : Fuentes_1988_Mol.Cell.Biochem_81_53 |
PubMedID: 3173345 |
Title : A 13 kDa fragment is responsible for the hydrophobic aggregation of brain G4 acetylcholinesterase - Fuentes_1988_Biochem.J_256_1047 |
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PubMedSearch : Fuentes_1988_Biochem.J_256_1047 |
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Title : Axons grow in the aging rat but fast transport and acetylcholinesterase content remain unchanged - Inestrosa_1988_Brain.Res_441_331 |
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PubMedSearch : Inestrosa_1988_Brain.Res_441_331 |
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Title : Co-solubilization of asymmetric acetylcholinesterase and dermatan sulfate proteoglycan from the extracellular matrix of rat skeletal muscles - Brandan_1987_FEBS.Lett_213_159 |
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PubMedSearch : Brandan_1987_FEBS.Lett_213_159 |
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Title : Acetylcholinesterase from bovine caudate nucleus is attached to membranes by a novel subunit distinct from those of acetylcholinesterases in other tissues - Inestrosa_1987_J.Biol.Chem_262_4441 |
Author(s) : Inestrosa NC , Roberts WL , Marshall TL , Rosenberry TL |
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PubMedSearch : Inestrosa_1987_J.Biol.Chem_262_4441 |
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Title : The synaptic form of acetylcholinesterase binds to cell-surface heparan sulfate proteoglycans - Brandan_1986_J.Neurosci.Res_15_185 |
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PubMedSearch : Brandan_1986_J.Neurosci.Res_15_185 |
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Title : Atypical distribution of asymmetric acetylcholinesterase in mutant PC12 pheochromocytoma cells lacking a cell surface heparan sulfate proteoglycan - Inestrosa_1985_J.Neurochem_45_86 |
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PubMedSearch : Inestrosa_1985_J.Neurochem_45_86 |
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Title : Anchorage of collagen-tailed acetylcholinesterase to the extracellular matrix is mediated by heparan sulfate proteoglycans - Brandan_1985_J.Cell.Biol_101_985 |
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PubMedSearch : Brandan_1985_J.Cell.Biol_101_985 |
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Title : Interaction of heparin with multimolecular aggregates of acetylcholinesterase - Torres_1985_Cell.Mol.Neurobiol_5_303 |
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PubMedSearch : Torres_1985_Cell.Mol.Neurobiol_5_303 |
PubMedID: 4064078 |
Title : Membrane-bound form of acetylcholinesterase activated during postnatal development of the rat somatosensory cortex - Inestrosa_1985_Dev.Neurosci_7_120 |
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PubMedSearch : Inestrosa_1985_Dev.Neurosci_7_120 |
PubMedID: 2415318 |
Title : Acetylcholinesterase is functional in embryonic rat muscle before its accumulation at the sites of nerve-muscle contact - Ziskind-Conhaim_1984_Dev.Biol_103_369 |
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PubMedSearch : Ziskind-Conhaim_1984_Dev.Biol_103_369 |
PubMedID: 6202574 |
Title : Age-related responses of skeletal muscle after ectopic innervation, with particular reference to 16S acetylcholinesterase, in adult rats - Maldonado_1984_J.Neurochem_43_375 |
Author(s) : Maldonado M , Ramirez BU , Ruiz G , Yamuy J , Inestrosa NC |
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PubMedSearch : Maldonado_1984_J.Neurochem_43_375 |
PubMedID: 6736957 |
Title : Binding of the asymmetric forms of acetylcholinesterase to heparin - Brandan_1984_Biochem.J_221_415 |
Author(s) : Brandan E , Inestrosa NC |
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Title : The electric organ of Discopyge tschudii: its innervated face and the biology of acetylcholinesterase - Mendez_1984_Cell.Mol.Neurobiol_4_125 |
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PubMedSearch : Mendez_1984_Cell.Mol.Neurobiol_4_125 |
PubMedID: 6488242 |
Title : Subcellular localization of acetylcholinesterase molecular forms in endplate regions of adult mammalian skeletal muscle - Fernandez_1984_Neurochem.Res_9_1211 |
Author(s) : Fernandez HL , Inestrosa NC , Stiles JR |
Ref : Neurochemical Research , 9 :1211 , 1984 |
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PubMedSearch : Fernandez_1984_Neurochem.Res_9_1211 |
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Title : 16S acetylcholinesterase of the extracellular matrix is assembled within mouse muscle cells in culture - Inestrosa_1984_Biochem.J_217_377 |
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PubMedSearch : Inestrosa_1984_Biochem.J_217_377 |
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Title : The A12 acetylcholinesterase and polypeptide composition of electric organ basal lamina of Electrophorus and some Torpedinae fishes - Inestrosa_1983_Cell.Biochem.Func_1_41 |
Author(s) : Inestrosa NC , Mendez B |
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PubMedSearch : Inestrosa_1983_Cell.Biochem.Func_1_41 |
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Title : Heparin solubilizes asymmetric acetylcholinesterase from rat neuromuscular junction - Torres_1983_FEBS.Lett_154_265 |
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Title : Increase of muscle peroxisomal enzymes and myotonia induced by nafenopin, a hypolipidemic drug - Behrens_1983_Muscle.Nerve_6_154 |
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PubMedSearch : Behrens_1983_Muscle.Nerve_6_154 |
PubMedID: 6855799 |
Title : Developmental regulation of 16S acetylcholinesterase and acetylcholine receptors in a mouse muscle cell line - Inestrosa_1983_Exp.Cell.Res_147_393 |
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PubMedSearch : Torres_1983_Biochem.J_215_201 |
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Title : Aneural muscle cell cultures make synaptic basal lamina components - |
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Ref : Nature , 295 :143 , 1982 |
PubMedID: 7035963 |
Title : Association of the synaptic form of acetylcholinesterase with extracellular matrix in cultured mouse muscle cells - Inestrosa_1982_Cell_29_71 |
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PubMedSearch : Inestrosa_1982_Cell_29_71 |
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Title : Cellular localization of the molecular forms of acetylcholinesterase in rat pheochromocytoma PC12 cells treated with nerve growth factor - Inestrosa_1981_J.Neurosci_1_1260 |
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Title : Acetylcholinesterase aggregates in a newly formed motor nerve-smooth muscle junction - Mendez_1981_Brain.Res.Bull_7_17 |
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PubMedSearch : Mendez_1981_Brain.Res.Bull_7_17 |
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Title : Acetylcholinesterase like that of skeletal muscle in smooth muscle reinnervated by a motor nerve - |
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Ref : Nature , 280 :504 , 1979 |
PubMedID: 460431 |
Title : Effects of denervation and of axoplasmic transport blockage on the in vitro release of muscle endplate acetylcholinesterase - |
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Ref : Journal of Neurochemistry , 28 :941 , 1977 |
PubMedID: 68100 |
Title : Role of axoplasmic transport in neurotrophic regulation of muscle end plate acetylcholinesterase - |
Author(s) : Ferdandez HL , Inestrosa NC |
Ref : Nature , 262 :55 , 1976 |
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