Title : Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity - Green_2023_J.Med.Chem__ |
Author(s) : Green SR , Wilson C , Eadsforth TC , Punekar AS , Tamaki FK , Wood G , Caldwell N , Forte B , Norcross NR , Kiczun M , Post JM , Lopez-Roman EM , Engelhart CA , Lukac I , Zuccotto F , Epemolu O , Boshoff HIM , Schnappinger D , Walpole C , Gilbert IH , Read KD , Wyatt PG , Baragana B |
Ref : Journal of Medicinal Chemistry , : , 2023 |
Abstract : |
PubMedSearch : Green_2023_J.Med.Chem__ |
PubMedID: 37948640 |
Gene_locus related to this paper: myctu-PKS13 |
Title : Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13\; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target - Wilson_2022_J.Med.Chem_65_409 |
Author(s) : Wilson C , Ray P , Zuccotto F , Hernandez J , Aggarwal A , Mackenzie C , Caldwell N , Taylor M , Huggett M , Mathieson M , Murugesan D , Smith A , Davis S , Cocco M , Parai MK , Acharya A , Tamaki F , Scullion P , Epemolu O , Riley J , Stojanovski L , Lopez-Roman EM , Torres-Gomez PA , Toledo AM , Guijarro-Lopez L , Camino I , Engelhart CA , Schnappinger D , Massoudi LM , Lenaerts A , Robertson GT , Walpole C , Matthews D , Floyd D , Sacchettini JC , Read KD , Encinas L , Bates RH , Green SR , Wyatt PG |
Ref : Journal of Medicinal Chemistry , 65 :409 , 2022 |
Abstract : |
PubMedSearch : Wilson_2022_J.Med.Chem_65_409 |
PubMedID: 34910486 |
Gene_locus related to this paper: myctu-PKS13 |
Title : An epoxide hydrolase from endophytic Streptomyces shows unique structural features and wide biocatalytic activity - Tormet-Gonzalez_2020_Acta.Crystallogr.D.Struct.Biol_76_868 |
Author(s) : Tormet-Gonzalez GD , Wilson C , de Oliveira GS , dos Santos JC , de Oliveira LG , Dias MVB |
Ref : Acta Crystallographica D Struct Biol , 76 :868 , 2020 |
Abstract : |
PubMedSearch : Tormet-Gonzalez_2020_Acta.Crystallogr.D.Struct.Biol_76_868 |
PubMedID: 32876062 |
Gene_locus related to this paper: strsq-b1eph2 |
Title : Structure of a soluble epoxide hydrolase identified in Trichoderma reesei - Wilson_2017_Biochim.Biophys.Acta_1865_1039 |
Author(s) : Wilson C , de Oliveira GS , Adriani PP , Chambergo FS , Dias MVB |
Ref : Biochimica & Biophysica Acta , 1865 :1039 , 2017 |
Abstract : |
PubMedSearch : Wilson_2017_Biochim.Biophys.Acta_1865_1039 |
PubMedID: 28502798 |
Gene_locus related to this paper: hypjq-g0r7e2 |
Title : Prolonged Paralysis Following Emergent Cesarean Section with Succinylcholine Despite Normal Dibucaine Number - Ellison_2016_W.V.Med.J_112_44 |
Author(s) : Ellison M , Grose B , Howell S , Wilson C , Lenz J , Driver R |
Ref : W V Med J , 112 :44 , 2016 |
Abstract : |
PubMedSearch : Ellison_2016_W.V.Med.J_112_44 |
PubMedID: 27025119 |
Title : Species variation in small molecule components of animal vitreous - Mains_2012_Invest.Ophthalmol.Vis.Sci_53_4778 |
Author(s) : Mains J , Tan LE , Zhang T , Young L , Shi R , Wilson C |
Ref : Invest Ophthalmol Vis Sci , 53 :4778 , 2012 |
Abstract : |
PubMedSearch : Mains_2012_Invest.Ophthalmol.Vis.Sci_53_4778 |
PubMedID: 22669713 |
Title : Efficacy and safety of the dipeptidyl peptidase-4 inhibitor alogliptin in patients with type 2 diabetes inadequately controlled by glyburide monotherapy - Pratley_2009_Diabetes.Obes.Metab_11_167 |
Author(s) : Pratley RE , Kipnes MS , Fleck PR , Wilson C , Mekki Q |
Ref : Diabetes Obes Metab , 11 :167 , 2009 |
Abstract : |
PubMedSearch : Pratley_2009_Diabetes.Obes.Metab_11_167 |
PubMedID: 19125778 |
Title : Muscarinic and nicotinic cholinergic mechanisms in the mesostriatal dopamine systems - Zhou_2003_Neuroscientist_9_23 |
Author(s) : Zhou FM , Wilson C , Dani JA |
Ref : Neuroscientist , 9 :23 , 2003 |
Abstract : |
PubMedSearch : Zhou_2003_Neuroscientist_9_23 |
PubMedID: 12580337 |
Title : Nonstriatal dopamine D1 receptors regulate striatal acetylcholine release in vivo - Acquas_1997_J.Pharmacol.Exp.Ther_281_360 |
Author(s) : Acquas E , Wilson C , Fibiger HC |
Ref : Journal of Pharmacology & Experimental Therapeutics , 281 :360 , 1997 |
Abstract : |
PubMedSearch : Acquas_1997_J.Pharmacol.Exp.Ther_281_360 |
PubMedID: 9103518 |