Title : Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13\; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target - Wilson_2022_J.Med.Chem_65_409 |
Author(s) : Wilson C , Ray P , Zuccotto F , Hernandez J , Aggarwal A , Mackenzie C , Caldwell N , Taylor M , Huggett M , Mathieson M , Murugesan D , Smith A , Davis S , Cocco M , Parai MK , Acharya A , Tamaki F , Scullion P , Epemolu O , Riley J , Stojanovski L , Lopez-Roman EM , Torres-Gomez PA , Toledo AM , Guijarro-Lopez L , Camino I , Engelhart CA , Schnappinger D , Massoudi LM , Lenaerts A , Robertson GT , Walpole C , Matthews D , Floyd D , Sacchettini JC , Read KD , Encinas L , Bates RH , Green SR , Wyatt PG |
Ref : Journal of Medicinal Chemistry , 65 :409 , 2022 |
Abstract : |
PubMedSearch : Wilson_2022_J.Med.Chem_65_409 |
PubMedID: 34910486 |
Gene_locus related to this paper: myctu-PKS13 |
Title : Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13 - Aggarwal_2017_Cell_170_249 |
Author(s) : Aggarwal A , Parai MK , Shetty N , Wallis D , Woolhiser L , Hastings C , Dutta NK , Galaviz S , Dhakal RC , Shrestha R , Wakabayashi S , Walpole C , Matthews D , Floyd D , Scullion P , Riley J , Epemolu O , Norval S , Snavely T , Robertson GT , Rubin EJ , Ioerger TR , Sirgel FA , van der Merwe R , van Helden PD , Keller P , Bottger EC , Karakousis PC , Lenaerts AJ , Sacchettini JC |
Ref : Cell , 170 :249 , 2017 |
Abstract : |
PubMedSearch : Aggarwal_2017_Cell_170_249 |
PubMedID: 28669536 |
Gene_locus related to this paper: myctu-PKS13 |
Title : Genome of the bacterium Streptococcus pneumoniae strain R6 - Hoskins_2001_J.Bacteriol_183_5709 |
Author(s) : Hoskins J , Alborn WE, Jr. , Arnold J , Blaszczak LC , Burgett S , DeHoff BS , Estrem ST , Fritz L , Fu DJ , Fuller W , Geringer C , Gilmour R , Glass JS , Khoja H , Kraft AR , Lagace RE , LeBlanc DJ , Lee LN , Lefkowitz EJ , Lu J , Matsushima P , McAhren SM , McHenney M , McLeaster K , Mundy CW , Nicas TI , Norris FH , O'Gara M , Peery RB , Robertson GT , Rockey P , Sun PM , Winkler ME , Yang Y , Young-Bellido M , Zhao G , Zook CA , Baltz RH , Jaskunas SR , Rosteck PR, Jr. , Skatrud PL , Glass JI |
Ref : Journal of Bacteriology , 183 :5709 , 2001 |
Abstract : |
PubMedSearch : Hoskins_2001_J.Bacteriol_183_5709 |
PubMedID: 11544234 |
Gene_locus related to this paper: strp2-q04l35 , strpj-b8zns7 , strpn-AXE1 , strpn-b2dz20 , strpn-pepx , strpn-SP0614 , strpn-SP0777 , strpn-SP0902 , strpn-SP1343 |