Title : Design and discovery of anthranilamide derivatives as a potential treatment for neurodegenerative disorders via targeting cholinesterases and monoamine oxidases - Zaib_2024_Int.J.Biol.Macromol__132748 |
Author(s) : Zaib S , Khan I , Ali HS , Younas MT , Ibrar A , Al-Odayni AB , Al-Kahtani AA |
Ref : Int J Biol Macromol , :132748 , 2024 |
Abstract : |
PubMedSearch : Zaib_2024_Int.J.Biol.Macromol__132748 |
PubMedID: 38821306 |
Title : Pyrimidine-morpholine hybrids as potent druggable therapeutics for Alzheimer's disease: Synthesis, biochemical and in silico analyses - Zaib_2023_Bioorg.Chem_141_106868 |
Author(s) : Zaib S , Younas MT , Khan I , Ali HS , McAdam CJ , White JM , Jaber F , Awwad NS , Ibrahium HA |
Ref : Bioorg Chem , 141 :106868 , 2023 |
Abstract : |
PubMedSearch : Zaib_2023_Bioorg.Chem_141_106868 |
PubMedID: 37738768 |
Title : Ultrasound-Assisted Synthesis of Piperidinyl-Quinoline Acylhydrazones as New Anti-Alzheimer's Agents: Assessment of Cholinesterase Inhibitory Profile, Molecular Docking Analysis, and Drug-like Properties - Munir_2023_Molecules_28_ |
Author(s) : Munir R , Zaib S , Zia-Ur-Rehman M , Hussain N , Chaudhry F , Younas MT , Zahra FT , Tajammul Z , Javid N , Dera AA , Ogaly HA , Khan I |
Ref : Molecules , 28 : , 2023 |
Abstract : |
PubMedSearch : Munir_2023_Molecules_28_ |
PubMedID: 36903376 |
Title : Discovery of potent and selective dual cholinesterases and beta-secretase inhibitors in pomegranate as a treatment for Alzheimer's disease - Yousof_2022_Bioorg.Chem_129_106137 |
Author(s) : Yousof Ali M , Zaib S , Jannat S , Khan I |
Ref : Bioorg Chem , 129 :106137 , 2022 |
Abstract : |
PubMedSearch : Yousof_2022_Bioorg.Chem_129_106137 |
PubMedID: 36108590 |
Title : Hybrid Quinoline-Thiosemicarbazone Therapeutics as a New Treatment Opportunity for Alzheimer's Disease-Synthesis, In Vitro Cholinesterase Inhibitory Potential and Computational Modeling Analysis - Zaib_2021_Molecules_26_ |
Author(s) : Zaib S , Munir R , Younas MT , Kausar N , Ibrar A , Aqsa S , Shahid N , Asif TT , Alsaab HO , Khan I |
Ref : Molecules , 26 : , 2021 |
Abstract : |
PubMedSearch : Zaib_2021_Molecules_26_ |
PubMedID: 34770983 |
Title : Microwave-Assisted Synthesis of (Piperidin-1-yl)quinolin-3-yl)methylene)hydrazinecarbothioamides as Potent Inhibitors of Cholinesterases: A Biochemical and In Silico Approach - Munir_2021_Molecules_26_ |
Author(s) : Munir R , Zia-Ur-Rehman M , Murtaza S , Zaib S , Javid N , Awan SJ , Iftikhar K , Athar MM , Khan I |
Ref : Molecules , 26 : , 2021 |
Abstract : |
PubMedSearch : Munir_2021_Molecules_26_ |
PubMedID: 33513837 |
Title : Structure-based virtual screening of dipeptidyl peptidase 4 inhibitors and their in vitro analysis - Rahman_2020_Comput.Biol.Chem__107326 |
Author(s) : Rahman SU , Ali HS , Jafari B , Zaib S , Hameed A , Al-Kahraman Y , Langer P , Iqbal J |
Ref : Comput Biol Chem , :107326 , 2020 |
Abstract : |
PubMedSearch : Rahman_2020_Comput.Biol.Chem__107326 |
PubMedID: 32739275 |
Title : Investigation of potent inhibitors of cholinesterase based on thiourea and pyrazoline derivatives: Synthesis, inhibition assay and molecular modeling studies - Mumtaz_2019_Bioorg.Chem_90_103036 |
Author(s) : Mumtaz A , Majeed A , Zaib S , Ur Rahman S , Hameed S , Saeed A , Rafique H , Mughal E , Maalik A , Hussain I , Iqbal J |
Ref : Bioorg Chem , 90 :103036 , 2019 |
Abstract : |
PubMedSearch : Mumtaz_2019_Bioorg.Chem_90_103036 |
PubMedID: 31271943 |
Title : Quinolinic Carboxylic Acid Derivatives as Potential Multi-target Compounds for Neurodegeneration: Monoamine Oxidase and Cholinesterase Inhibition - Khan_2018_Med.Chem_14_74 |
Author(s) : Khan NA , Khan I , Abid SMA , Zaib S , Ibrar A , Andleeb H , Hameed S , Iqbal J |
Ref : Med Chem , 14 :74 , 2018 |
Abstract : |
PubMedSearch : Khan_2018_Med.Chem_14_74 |
PubMedID: 28545383 |
Title : Synthesis, molecular modelling and biological evaluation of tetrasubstituted thiazoles towards cholinesterase enzymes and cytotoxicity studies - Mumtaz_2018_Bioorg.Chem_78_141 |
Author(s) : Mumtaz A , Shoaib M , Zaib S , Shah MS , Bhatti HA , Saeed A , Hussain I , Iqbal J |
Ref : Bioorg Chem , 78 :141 , 2018 |
Abstract : |
PubMedSearch : Mumtaz_2018_Bioorg.Chem_78_141 |
PubMedID: 29567428 |
Title : Identification of New Chromenone Derivatives as Cholinesterase Inhibitors and Molecular Docking Studies - Iqbal_2018_Med.Chem_14_809 |
Author(s) : Iqbal J , Abbasi MSA , Zaib S , Afridi S , Furtmann N , Bajorath J , Langer P |
Ref : Med Chem , 14 :809 , 2018 |
Abstract : |
PubMedSearch : Iqbal_2018_Med.Chem_14_809 |
PubMedID: 29473519 |
Title : Modification of Bischler-Mohlau indole derivatives through palladium catalyzed Suzuki reaction as effective cholinesterase inhibitors, their kinetic and molecular docking studies - Parveen_2017_Bioorg.Chem_76_166 |
Author(s) : Parveen S , Shah MS , Zaib S , Gul T , Khan KM , Iqbal J , Hassan A |
Ref : Bioorg Chem , 76 :166 , 2017 |
Abstract : |
PubMedSearch : Parveen_2017_Bioorg.Chem_76_166 |
PubMedID: 29175588 |
Title : Synthesis, cholinesterase inhibition and molecular modelling studies of coumarin linked thiourea derivatives - Saeed_2015_Bioorg.Chem_63_58 |
Author(s) : Saeed A , Zaib S , Ashraf S , Iftikhar J , Muddassar M , Zhang KY , Iqbal J |
Ref : Bioorg Chem , 63 :58 , 2015 |
Abstract : |
PubMedSearch : Saeed_2015_Bioorg.Chem_63_58 |
PubMedID: 26440714 |
Title : Exploration of a library of triazolothiadiazole and triazolothiadiazine compounds as a highly potent and selective family of cholinesterase and monoamine oxidase inhibitors: design, synthesis, X-ray diffraction analysis and molecular docking studies - Khan_2015_RSC.Adv_5_21249 |
Author(s) : Khan I , Bakht SM , Ibrar A , Abbas S , Hameed S , White JM , Rana UA , Zaib S , Shahid M , IqbalJ |
Ref : RSC Adv , 5 :21249 , 2015 |
Abstract : |
PubMedSearch : Khan_2015_RSC.Adv_5_21249 |
PubMedID: |
Title : Novel structural hybrids of pyrazolobenzothiazines with benzimidazoles as cholinesterase inhibitors - Aslam_2014_Eur.J.Med.Chem_78C_106 |
Author(s) : Aslam S , Zaib S , Ahmad M , Gardiner JM , Ahmad A , Hameed A , Furtmann N , Gutschow M , Bajorath J , Iqbal J |
Ref : Eur Journal of Medicinal Chemistry , 78C :106 , 2014 |
Abstract : |
PubMedSearch : Aslam_2014_Eur.J.Med.Chem_78C_106 |
PubMedID: 24681070 |
Title : Synthesis, crystal structure and biological evaluation of some novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines - Khan_2014_Eur.J.Med.Chem_78C_167 |
Author(s) : Khan I , Zaib S , Ibrar A , Rama NH , Simpson J , Iqbal J |
Ref : Eur Journal of Medicinal Chemistry , 78C :167 , 2014 |
Abstract : |
PubMedSearch : Khan_2014_Eur.J.Med.Chem_78C_167 |
PubMedID: 24681981 |
Title : Synthesis, cytotoxicity and molecular modelling studies of new phenylcinnamide derivatives as potent inhibitors of cholinesterases - Saeed_2014_Eur.J.Med.Chem_78C_43 |
Author(s) : Saeed A , Mahesar PA , Zaib S , Khan MS , Matin A , Shahid M , Iqbal J |
Ref : Eur Journal of Medicinal Chemistry , 78C :43 , 2014 |
Abstract : |
PubMedSearch : Saeed_2014_Eur.J.Med.Chem_78C_43 |
PubMedID: 24675179 |
Title : Active compounds from a diverse library of triazolothiadiazole and triazolothiadiazine scaffolds: Synthesis, crystal structure determination, cytotoxicity, cholinesterase inhibitory activity, and binding mode analysis - Khan_2014_Bioorg.Med.Chem_22_6163 |
Author(s) : Khan I , Ibrar A , Zaib S , Ahmad S , Furtmann N , Hameed S , Simpson J , Bajorath J , Iqbal J |
Ref : Bioorganic & Medicinal Chemistry , 22 :6163 , 2014 |
Abstract : |
PubMedSearch : Khan_2014_Bioorg.Med.Chem_22_6163 |
PubMedID: 25257911 |