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Family Report for: Prolyl_oligopeptidase_S9

Prolyl_oligopeptidase_S9



Relationship
Block X
Parent Family : Peptidase_S9

Comment
Prolyl_oligopeptidase_S9 are serine protease of the clan S family S9 in MEROPS database. Previously this family contained also all the subfamilies ACPH_Peptidase_S9, Glutamyl_Peptidase_S9, DPP4N_Peptidase_S9, S9N_Peptidase_S9. Now it contains entries that do not fit in these well defined sub families. Few proteins characterized in this family. Aspergillus fumigatus DPP5 and DPP4.(Beauvais et al.) DPP5 unique substrate specificity limited to the hydrolysis of X-Ala, His-Ser, and Ser-Tyr dipeptide and not post Proline

Database
Sequences
Interpro
|
IPR001375 (Peptidase_S9)
PIRSF
|
Pdoc
|
PFam
|
PF00326 (Peptidase_S9)
Prints
|
Prosite
|
no EC number



Peptide in
|Fasta
Nucleotide in
|Fasta
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
Dendrogram
|Graphical display, obtained with the dnd file produced by Clustalw

References
    Title: A bacterial acyl aminoacyl peptidase couples flexibility and stability as a result of cold adaptation
    Brocca S, Ferrari C, Barbiroli A, Pesce A, Lotti M, Nardini M
    Ref: Febs J, 283:4310, 2016 : PubMed

            

    Title: Biochemical and antigenic characterization of a new dipeptidyl-peptidase isolated from Aspergillus fumigatus
    Beauvais A, Monod M, Debeaupuis JP, Diaquin M, Kobayashi H, Latge JP
    Ref: Journal of Biological Chemistry, 272:6238, 1997 : PubMed

            

Other Papers


No structure scheme yet for this family

Structures in Prolyl_oligopeptidase_S9 family (2)

Genes Proteins in Prolyl_oligopeptidase_S9 family (189)

Fragments of genes in Prolyl_oligopeptidase_S9 family (8)

Substrates of some enzymes in the Prolyl_oligopeptidase_S9 family (5)

No Inhibitor



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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