Family: Prolyl_oligopeptidase_S9

Block: X

Parent Family: Peptidase_S9


Prolyl_oligopeptidase_S9 are serine protease of the clan S family S9 in MEROPS database. Previously this family contained also all the subfamilies ACPH_Peptidase_S9, Glutamyl_Peptidase_S9, DPP4N_Peptidase_S9, S9N_Peptidase_S9. Now it contains entries that do not fit in these well defined sub families. Few proteins characterized in this family. Aspergillus fumigatus DPP5 and DPP4 (Beauvais et al.) DPP5 unique substrate specificity limited to the hydrolysis of X-Ala, His-Ser, and Ser-Tyr dipeptide and not post Proline


Interpro : IPR001375 Peptidase_S9


Pdoc : No Pdoc

Pfam : PF00326 Peptidase_S9

Prints : No Print

EC Number : No EC Number


Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

Structures (2)

Genes Proteins in Prolyl_oligopeptidase_S9 family (189)

Fragments of genes in Prolyl_oligopeptidase_S9 family (8)

Structures in Prolyl_oligopeptidase_S9 family (2)

Substrates in Prolyl_oligopeptidase_S9 family (5)

No Inhibitor

References (2)

Title : A bacterial acyl aminoacyl peptidase couples flexibility and stability as a result of cold adaptation - Brocca_2016_FEBS.J_283_4310
Author(s) : Brocca S , Ferrari C , Barbiroli A , Pesce A , Lotti M , Nardini M
Ref : Febs J , 283 :4310 , 2016
PubMedID: 27739253
Gene_locus related to this paper: spops-e1vfe0

Title : Biochemical and antigenic characterization of a new dipeptidyl-peptidase isolated from Aspergillus fumigatus - Beauvais_1997_J.Biol.Chem_272_6238
Author(s) : Beauvais A , Monod M , Debeaupuis JP , Diaquin M , Kobayashi H , Latge JP
Ref : Journal of Biological Chemistry , 272 :6238 , 1997
PubMedID: 9045640
Gene_locus related to this paper: aspfc-dpp5