9sphi-b5apj0

Sphingobacterium sp.; Sphingobacterium faecium Putative streptothricin resistance protein; macrolide esterase EstT

Comment

Other strains: Sphingobacterium sp. PM2-P1-29\; Sphingobacterium faecium strain WB1 plasmid pWB1\; Moraxella pluranimalium\; Riemerella anatipestifer (Moraxella anatipestifer)\; Glaesserella parasuis (Haemophilus parasuis)\; uncultured bacterium

Relationship

Family : Aclacinomycin-methylesterase_RdmC

Block : X

Position in NCBI Life Tree : Sphingobacterium sp. PM2-P1-29

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > FCB group N E > Bacteroidetes\/Chlorobi group N E > Bacteroidetes N E > Sphingobacteriia N E > Sphingobacteriales N E > Sphingobacteriaceae N E > Sphingobacterium N E > Sphingobacterium sp. PM2-P1-29 N E > cellular organisms N E > Bacteria N E > FCB group N E > Bacteroidetes\/Chlorobi group N E > Bacteroidetes N E > Sphingobacteriia N E > Sphingobacteriales N E > Sphingobacteriaceae N E > Sphingobacterium N E > Sphingobacterium sp. PM2-P1-29 N E > cellular organisms N E > Bacteria N E > FCB group N E > Bacteroidetes\/Chlorobi group N E > Bacteroidetes N E > Sphingobacteriia N E > Sphingobacteriales N E > Sphingobacteriaceae N E > Sphingobacterium N E > Sphingobacterium sp. PM2-P1-29 N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

Leucomycin-a5 Tildipirosin Tilmicosin Tylosin

No inhibitor

Database

EU864422 WP_046701559

A0A077XLA7 A0A127SFE6 A0A127SFQ5 A0A127SZT0 A0A1T0CLZ1 A0A6B9LFW9 B5APJ0 G3EN46 K1U9Z8

Sequence

Peptide

MKEKIIKTNG IELCTESFGN KKNPAILLVA GATVSMLYWD TEFCQQLSEK GFFVIRYDNR DVGKSTNYEP GSTPYDIVDL TNDAISILDG YKIDKAHFVG ISLGGLISQI ASIKFADRVN SLTLMSSGPW GDSDPTIPEM DTSILDFHSK AGTVNWTNED SVVNYLIQGA ELMSGKKQFD KQRSEKLIRA EFNRANNYIS MFNHAALQGG EEYWNRLNEI KQPTLIIHGT DDKIWHYKNA GFLLEKIKGS NLITLEGTGH ELHVDDWKSI IDGIEKHIND

References (6)

Title : A neglected and emerging antimicrobial resistance gene encodes for a serine-dependent macrolide esterase - Dhindwal_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2219827120

Author(s) : Dhindwal P , Thompson C , Kos D , Planedin K , Jain R , Jelinski M , Ruzzini A

Ref : Proc Natl Acad Sci U S A , 120 :e2219827120 , 2023

Abstract :

PubMedSearch : Dhindwal_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2219827120

PubMedID: 36791107

Gene_locus related to this paper: 9sphi-b5apj0

Title : A neglected and emerging antimicrobial resistance gene encodes for a serine-dependent macrolide esterase - Dhindwal_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2219827120

Author(s) : Dhindwal P , Thompson C , Kos D , Planedin K , Jain R , Jelinski M , Ruzzini A

Ref : Proc Natl Acad Sci U S A , 120 :e2219827120 , 2023

Abstract :

PubMedSearch : Dhindwal_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2219827120

PubMedID: 36791107

Gene_locus related to this paper: 9sphi-b5apj0

Title : A neglected and emerging antimicrobial resistance gene encodes for a serine-dependent macrolide esterase - Dhindwal_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2219827120

Author(s) : Dhindwal P , Thompson C , Kos D , Planedin K , Jain R , Jelinski M , Ruzzini A

Ref : Proc Natl Acad Sci U S A , 120 :e2219827120 , 2023

Abstract :

PubMedSearch : Dhindwal_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2219827120

PubMedID: 36791107

Gene_locus related to this paper: 9sphi-b5apj0

Title : Sphingobacterium sp. strain PM2-P1-29 harbours a functional tet(X) gene encoding for the degradation of tetracycline - Ghosh_2009_J.Appl.Microbiol_106_1336

Author(s) : Ghosh S , Sadowsky MJ , Roberts MC , Gralnick JA , LaPara TM

Ref : J Appl Microbiol , 106 :1336 , 2009

Abstract :

PubMedSearch : Ghosh_2009_J.Appl.Microbiol_106_1336

PubMedID: 19187139

Gene_locus related to this paper: 9sphi-b5apj0

Title : Sphingobacterium sp. strain PM2-P1-29 harbours a functional tet(X) gene encoding for the degradation of tetracycline - Ghosh_2009_J.Appl.Microbiol_106_1336

Author(s) : Ghosh S , Sadowsky MJ , Roberts MC , Gralnick JA , LaPara TM

Ref : J Appl Microbiol , 106 :1336 , 2009

Abstract :

PubMedSearch : Ghosh_2009_J.Appl.Microbiol_106_1336

PubMedID: 19187139

Gene_locus related to this paper: 9sphi-b5apj0

Title : Sphingobacterium sp. strain PM2-P1-29 harbours a functional tet(X) gene encoding for the degradation of tetracycline - Ghosh_2009_J.Appl.Microbiol_106_1336

Author(s) : Ghosh S , Sadowsky MJ , Roberts MC , Gralnick JA , LaPara TM

Ref : J Appl Microbiol , 106 :1336 , 2009

Abstract :

PubMedSearch : Ghosh_2009_J.Appl.Microbiol_106_1336

PubMedID: 19187139

Gene_locus related to this paper: 9sphi-b5apj0

9sphi-b5apj0

Comment

Relationship

Molecular evidence

Mutation (0)

Structure (0)

Kinetic (0)

Disease (0)

Substrate (4)

Inhibitor (0)

Database

Genbank (2)

Interpro (9)

Pfam (9)

UniProt (9)

PIRSF (9)

SUPERFAM (9)

Sequence

Peptide

References (6)

1. A neglected and emerging antimicrobial resistance gene encodes for a serine-dependent macrolide esterase - Dhindwal_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2219827120

2. A neglected and emerging antimicrobial resistance gene encodes for a serine-dependent macrolide esterase - Dhindwal_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2219827120

3. A neglected and emerging antimicrobial resistance gene encodes for a serine-dependent macrolide esterase - Dhindwal_2023_Proc.Natl.Acad.Sci.U.S.A_120_e2219827120

4. Sphingobacterium sp. strain PM2-P1-29 harbours a functional tet(X) gene encoding for the degradation of tetracycline - Ghosh_2009_J.Appl.Microbiol_106_1336

5. Sphingobacterium sp. strain PM2-P1-29 harbours a functional tet(X) gene encoding for the degradation of tetracycline - Ghosh_2009_J.Appl.Microbiol_106_1336

6. Sphingobacterium sp. strain PM2-P1-29 harbours a functional tet(X) gene encoding for the degradation of tetracycline - Ghosh_2009_J.Appl.Microbiol_106_1336