Tylosin
General
Type : Macrolide, Polyketide, Natural, Antibiotic
Chemical_Nomenclature : 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
Canonical SMILES : CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)C)COC4C(C(C(C(O4)C)O)OC)OC
InChI : InChI=1S\/C46H77NO17\/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35\/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3\/b15-14+,23-18+\/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-\/m1\/s1
InChIKey : WBPYTXDJUQJLPQ-VMXQISHHSA-N
Other name(s) : Tylosin A || Tylosine || Tylan || Tylocine || CHEBI:17658 || SCHEMBL3081 || CHEMBL42743 || DB11475
MW : 916.1
Formula : C46H77NO17
CAS_number : 1405-54-5
PubChem : 5280440
UniChem : WBPYTXDJUQJLPQ-VMXQISHHSA-N
Target
Structures : No structure
Families : Aclacinomycin-methylesterase_RdmC
References (1)
| Title : The global distribution of the macrolide esterase EstX from the alpha\/beta hydrolase superfamily - Lin_2024_Commun.Biol_7_781 |
| Author(s) : Lin J , Lv H , Wang T , Tao H , Zhong Y , Zhou Y , Tang Y , Xie F , Zhuang G , Xu C , Chu Y , Wang X , Yang Y , Song T |
| Ref : Commun Biol , 7 :781 , 2024 |
| Abstract : |
| PubMedSearch : Lin_2024_Commun.Biol_7_781 |
| PubMedID: 38944651 |
| Gene_locus related to this paper: ecoli-estX |