Tilmicosin
Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease
General
Type : Macrolide, Polyketide, Natural, Antibiotic
Chemical_Nomenclature : (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-7-[2-[(3S,5R)-3,5-dimethylpiperidin-1-yl]ethyl]-16-ethyl-4-hydroxy-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione
Canonical SMILES : CCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)O)N(C)C)O)CCN3CC(CC(C3)C)C)C)C)COC4C(C(C(C(O4)C)O)OC)OC
InChI : InChI=1S\/C46H80N2O13\/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45\/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3\/b15-14+,25-19+\/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-\/m1\/s1
InChIKey : JTSDBFGMPLKDCD-XVFHVFLVSA-N
Other name(s) : Micotil || Tilmicosinum || Tilmicosina
MW : 869.1
Formula : C46H80N2O13
CAS_number : 108050-54-0
PubChem : 5282521
UniChem : JTSDBFGMPLKDCD-XVFHVFLVSA-N
Target
Structures : No structure
Families : Aclacinomycin-methylesterase_RdmC
References (1)
| Title : The global distribution of the macrolide esterase EstX from the alpha\/beta hydrolase superfamily - Lin_2024_Commun.Biol_7_781 |
| Author(s) : Lin J , Lv H , Wang T , Tao H , Zhong Y , Zhou Y , Tang Y , Xie F , Zhuang G , Xu C , Chu Y , Wang X , Yang Y , Song T |
| Ref : Commun Biol , 7 :781 , 2024 |
| Abstract : |
| PubMedSearch : Lin_2024_Commun.Biol_7_781 |
| PubMedID: 38944651 |
| Gene_locus related to this paper: ecoli-estX |