burga-GbnD6TE

Burkholderia gladioli (Pseudomonas marginata) (Phytomonas marginata) Thioesterase domain (GbnD6 TE domain) from the gladiolin PKS

Comment

Relationship

Family : Thioesterase

Block : X

Position in NCBI Life Tree : Burkholderia gladioli

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Proteobacteria N E > Betaproteobacteria N E > Burkholderiales N E > Burkholderiaceae N E > Burkholderia N E > Burkholderia gladioli N E

Molecular evidence

No mutation

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MAGERVSDTP TQRDPVFEIL QSRGRRSPAV WFHGSMGTVQ AYLGLARAIG DEVPFHAFQS RGLRGEDAPL ADLGEMAALY TRRLLARQPD ESRAFRLGGY SQGGLLAYEV TRQLQLAGRR VESLVMVDTP YAYGDMALKD DDDTDSLRLA IVYVNLLLMN GLGDFSDLAE VHRPGIDPAE LLPALVRAGI DRGLPYTPQA LGQLIERHHR VARANETAAR TYLPADLPHP GQPVVHYFAR RHPQVYFDPA RFSGPMVEWT NRYFADKDCA SRWQRHLPTW HHHATPAVDH FAMLTDSASF AAIVRTCREL YLGSGSTTDQ AGALLVSGPA

References (1)

Title : Discovery and Biosynthesis of Gladiolin: A Burkholderia gladioli Antibiotic with Promising Activity against Mycobacterium tuberculosis - Song_2017_J.Am.Chem.Soc_139_7974
Author(s) : Song L , Jenner M , Masschelein J , Jones C , Bull MJ , Harris SR , Hartkoorn RC , Vocat A , Romero-Canelon I , Coupland P , Webster G , Dunn M , Weiser R , Paisey C , Cole ST , Parkhill J , Mahenthiralingam E , Challis GL
Ref : Journal of the American Chemical Society , 139 :7974 , 2017
Abstract :
PubMedSearch : Song_2017_J.Am.Chem.Soc_139_7974
PubMedID: 28528545
Gene_locus related to this paper: burga-GbnD6TE