lache-u6f2k7
Lactobacillus helveticus highly active esterase. hydrolyzes chlorogenic acid
Comment
one of the most active CGA esterases known to date with a Km of 0.090 mM and a kcat of 82.1 s-1. Other strains: Lactobacillus helveticus (Lactobacillus suntoryeus) ( DPC 4571\; CIRM-BIA 951)
Relationship
Family : FAE-Bacterial-promiscuous
Block : X
Position in NCBI Life Tree : Lactobacillus helveticus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Lactobacillales N E > Lactobacillaceae N E > Lactobacillus N E > Lactobacillus helveticus N E > cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Lactobacillales N E > Lactobacillaceae N E > Lactobacillus N E > Lactobacillus helveticus N E > cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Lactobacillales N E > Lactobacillaceae N E > Lactobacillus N E > Lactobacillus helveticus N EMolecular evidence
No mutation
8SKM - Wild type chlorogenic acid esterase from Lactobacillus helveticus
8SKM - Wild type chlorogenic acid esterase from Lactobacillus helveticus
8SKM - Wild type chlorogenic acid esterase from Lactobacillus helveticus
8SLJ - K164A mutant of a chlorogenic acid esterase from Lactobacillus helveticus
8SLJ - K164A mutant of a chlorogenic acid esterase from Lactobacillus helveticus
8SLJ - K164A mutant of a chlorogenic acid esterase from Lactobacillus helveticus
No kinetic
No disease
No inhibitor
Sequence
Peptide
MSRITIERDG LTLVGDREEP FGEIYDMAII MHGFTANRNT DLLRQIADDL RDENVASVRF DFNGHGESDG KFEDMTVCNE IADGKAILDY VHTDPHVRDI FLVGHSQGGV VASMLAGLYP DVVKKVVLLA PAAQLKDDAL RGNTQGATYD PNHIPDVVPL VGNKLGMKVG GFYLRTAQVL PIYEVSQRFT RPVSVIAGTN DQVVDPKYAK KYDEVYENSE LHMIPNADHR FSGGYKDMAA DLTAQFLKPA F
References (9)
| Title : The structure of a Lactobacillus helveticus chlorogenic acid esterase and the dynamics of its insertion domain provide insights into substrate binding - Omori_2023_FEBS.Lett__ |
| Author(s) : Omori KK , Drucker CT , Okumura TLS , Carl NB , Dinn BT , Ly D , Sacapano KN , Tajii A , Owens CP |
| Ref : FEBS Letters , : , 2023 |
| Abstract : |
| PubMedSearch : Omori_2023_FEBS.Lett__ |
| PubMedID: 37698360 |
| Gene_locus related to this paper: lache-u6f2k7 |
| Title : The structure of a Lactobacillus helveticus chlorogenic acid esterase and the dynamics of its insertion domain provide insights into substrate binding - Omori_2023_FEBS.Lett__ |
| Author(s) : Omori KK , Drucker CT , Okumura TLS , Carl NB , Dinn BT , Ly D , Sacapano KN , Tajii A , Owens CP |
| Ref : FEBS Letters , : , 2023 |
| Abstract : |
| PubMedSearch : Omori_2023_FEBS.Lett__ |
| PubMedID: 37698360 |
| Gene_locus related to this paper: lache-u6f2k7 |
| Title : The structure of a Lactobacillus helveticus chlorogenic acid esterase and the dynamics of its insertion domain provide insights into substrate binding - Omori_2023_FEBS.Lett__ |
| Author(s) : Omori KK , Drucker CT , Okumura TLS , Carl NB , Dinn BT , Ly D , Sacapano KN , Tajii A , Owens CP |
| Ref : FEBS Letters , : , 2023 |
| Abstract : |
| PubMedSearch : Omori_2023_FEBS.Lett__ |
| PubMedID: 37698360 |
| Gene_locus related to this paper: lache-u6f2k7 |
| Title : A highly active esterase from Lactobacillus helveticus hydrolyzes chlorogenic acid in sunflower meal to prevent chlorogenic acid induced greening in sunflower protein isolates - Lo Verde_2022_Food.Res.Int_162_111996 |
| Author(s) : Lo Verde C , Pepra-Ameyaw NB , Drucker CT , Okumura TLS , Lyon KA , Muniz JC , Sermet CS , Were Senger L , Owens CP |
| Ref : Food Res Int , 162 :111996 , 2022 |
| Abstract : |
| PubMedSearch : Lo Verde_2022_Food.Res.Int_162_111996 |
| PubMedID: 36461298 |
| Gene_locus related to this paper: lache-u6f2k7 |
| Title : A highly active esterase from Lactobacillus helveticus hydrolyzes chlorogenic acid in sunflower meal to prevent chlorogenic acid induced greening in sunflower protein isolates - Lo Verde_2022_Food.Res.Int_162_111996 |
| Author(s) : Lo Verde C , Pepra-Ameyaw NB , Drucker CT , Okumura TLS , Lyon KA , Muniz JC , Sermet CS , Were Senger L , Owens CP |
| Ref : Food Res Int , 162 :111996 , 2022 |
| Abstract : |
| PubMedSearch : Lo Verde_2022_Food.Res.Int_162_111996 |
| PubMedID: 36461298 |
| Gene_locus related to this paper: lache-u6f2k7 |
| Title : A highly active esterase from Lactobacillus helveticus hydrolyzes chlorogenic acid in sunflower meal to prevent chlorogenic acid induced greening in sunflower protein isolates - Lo Verde_2022_Food.Res.Int_162_111996 |
| Author(s) : Lo Verde C , Pepra-Ameyaw NB , Drucker CT , Okumura TLS , Lyon KA , Muniz JC , Sermet CS , Were Senger L , Owens CP |
| Ref : Food Res Int , 162 :111996 , 2022 |
| Abstract : |
| PubMedSearch : Lo Verde_2022_Food.Res.Int_162_111996 |
| PubMedID: 36461298 |
| Gene_locus related to this paper: lache-u6f2k7 |
| Title : Characterization of Cinnamoyl Esterases from Different Lactobacilli and Bifidobacteria - Fritsch_2017_Curr.Microbiol_74_247 |
| Author(s) : Fritsch C , Jansch A , Ehrmann MA , Toelstede S , Vogel RF |
| Ref : Curr Microbiol , 74 :247 , 2017 |
| Abstract : |
| PubMedSearch : Fritsch_2017_Curr.Microbiol_74_247 |
| PubMedID: 27999938 |
| Gene_locus related to this paper: limf3-b2gdc2 , lache-u6f2k7 , bifa0-b8du06 , lacac-q5fi30 , lacga-q040s2 , lacpl-LP.2953 , lacre-q2bvr2 |
| Title : Characterization of Cinnamoyl Esterases from Different Lactobacilli and Bifidobacteria - Fritsch_2017_Curr.Microbiol_74_247 |
| Author(s) : Fritsch C , Jansch A , Ehrmann MA , Toelstede S , Vogel RF |
| Ref : Curr Microbiol , 74 :247 , 2017 |
| Abstract : |
| PubMedSearch : Fritsch_2017_Curr.Microbiol_74_247 |
| PubMedID: 27999938 |
| Gene_locus related to this paper: limf3-b2gdc2 , lache-u6f2k7 , bifa0-b8du06 , lacac-q5fi30 , lacga-q040s2 , lacpl-LP.2953 , lacre-q2bvr2 |
| Title : Characterization of Cinnamoyl Esterases from Different Lactobacilli and Bifidobacteria - Fritsch_2017_Curr.Microbiol_74_247 |
| Author(s) : Fritsch C , Jansch A , Ehrmann MA , Toelstede S , Vogel RF |
| Ref : Curr Microbiol , 74 :247 , 2017 |
| Abstract : |
| PubMedSearch : Fritsch_2017_Curr.Microbiol_74_247 |
| PubMedID: 27999938 |
| Gene_locus related to this paper: limf3-b2gdc2 , lache-u6f2k7 , bifa0-b8du06 , lacac-q5fi30 , lacga-q040s2 , lacpl-LP.2953 , lacre-q2bvr2 |