lache-u6f2k7

Lactobacillus helveticus highly active esterase. hydrolyzes chlorogenic acid

Comment

one of the most active CGA esterases known to date with a Km of 0.090 mM and a kcat of 82.1 s-1. Other strains: Lactobacillus helveticus (Lactobacillus suntoryeus) ( DPC 4571\; CIRM-BIA 951)

Relationship

Family : FAE-Bacterial-promiscuous

Block : X

Position in NCBI Life Tree : Lactobacillus helveticus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Lactobacillales N E > Lactobacillaceae N E > Lactobacillus N E > Lactobacillus helveticus N E

Molecular evidence

No mutation

No kinetic

No disease

No inhibitor

Sequence

Peptide

MSRITIERDG LTLVGDREEP FGEIYDMAII MHGFTANRNT DLLRQIADDL RDENVASVRF DFNGHGESDG KFEDMTVCNE IADGKAILDY VHTDPHVRDI FLVGHSQGGV VASMLAGLYP DVVKKVVLLA PAAQLKDDAL RGNTQGATYD PNHIPDVVPL VGNKLGMKVG GFYLRTAQVL PIYEVSQRFT RPVSVIAGTN DQVVDPKYAK KYDEVYENSE LHMIPNADHR FSGGYKDMAA DLTAQFLKPA F

References (3)

Title : The structure of a Lactobacillus helveticus chlorogenic acid esterase and the dynamics of its insertion domain provide insights into substrate binding - Omori_2023_FEBS.Lett__
Author(s) : Omori KK , Drucker CT , Okumura TLS , Carl NB , Dinn BT , Ly D , Sacapano KN , Tajii A , Owens CP
Ref : FEBS Letters , : , 2023
PubMedID: 37698360
Gene_locus related to this paper: lache-u6f2k7

Title : A highly active esterase from Lactobacillus helveticus hydrolyzes chlorogenic acid in sunflower meal to prevent chlorogenic acid induced greening in sunflower protein isolates - Lo Verde_2022_Food.Res.Int_162_111996
Author(s) : Lo Verde C , Pepra-Ameyaw NB , Drucker CT , Okumura TLS , Lyon KA , Muniz JC , Sermet CS , Were Senger L , Owens CP
Ref : Food Res Int , 162 :111996 , 2022
PubMedID: 36461298
Gene_locus related to this paper: lache-u6f2k7

Title : Characterization of Cinnamoyl Esterases from Different Lactobacilli and Bifidobacteria - Fritsch_2017_Curr.Microbiol_74_247
Author(s) : Fritsch C , Jansch A , Ehrmann MA , Toelstede S , Vogel RF
Ref : Curr Microbiol , 74 :247 , 2017
PubMedID: 27999938
Gene_locus related to this paper: limf3-b2gdc2 , lache-u6f2k7 , bifa0-b8du06 , lacac-q5fi30 , lacga-q040s2 , lacpl-LP.2953 , lacre-q2bvr2