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nicta-SABP2

Nicotiana tabacum (Common tobacco) salicylic acid-binding protein 2 mRNA, complete

Comment

this enzyme is close to Rubber tree hydroxynitrile lyase HbHNL. Few mutations can convert one activity to the other (Padhi et al. Nedrud et al.)

Relationship

Family : Hydroxynitrile_lyase

Block : X

Position in NCBI Life Tree : Nicotiana tabacum

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Viridiplantae N E > Streptophyta N E > Streptophytina N E > Embryophyta N E > Tracheophyta N E > Euphyllophyta N E > Spermatophyta N E > Magnoliophyta N E > Mesangiospermae N E > eudicotyledons N E > Gunneridae N E > Pentapetalae N E > asterids N E > lamiids N E > Solanales N E > Solanaceae N E > Nicotianoideae N E > Nicotianeae N E > Nicotiana N E > Nicotiana tabacum N E

Molecular evidence

Database

Sequence

Peptide

MKEGKHFVLV HGACHGGWSW YKLKPLLEAA GHKVTALDLA ASGTDLRKIE ELRTLYDYTL PLMELMESLS ADEKVILVGH SLGGMNLGLA MEKYPQKIYA AVFLAAFMPD SVHNSSFVLE QYNERTPAEN WLDTQFLPYG SPEEPLTSMF FGPKFLAHKL YQLCSPEDLA LASSLVRPSS LFMEDLSKAK YFTDERFGSV KRVYIVCTED KGIPEEFQRW QIDNIGVTEA IEIKGADHMA MLCEPQKLCA SLLEIAHKYN

References (7)

Title : Tobacco SABP2-interacting protein SIP428 is a SIR2 type deacetylase - Haq_2020_Plant.Physiol.Biochem_152_72
Author(s) : Haq MI , Thakuri BKC , Hobbs T , Davenport ML , Kumar D
Ref : Plant Physiol Biochem , 152 :72 , 2020
Abstract :
PubMedSearch : Haq_2020_Plant.Physiol.Biochem_152_72
PubMedID: 32388422
Gene_locus related to this paper: nicta-SABP2

Title : Comparison of Five Protein Engineering Strategies for Stabilizing an alpha\/beta-Hydrolase - Jones_2017_Biochemistry_56_6521
Author(s) : Jones BJ , Lim HY , Huang J , Kazlauskas RJ
Ref : Biochemistry , 56 :6521 , 2017
Abstract :
PubMedSearch : Jones_2017_Biochemistry_56_6521
PubMedID: 29087185
Gene_locus related to this paper: nicta-SABP2

Title : Stabilization of an alpha\/beta-Hydrolase by Introducing Proline Residues: Salicylic Acid Binding Protein 2 from Tobacco -
Author(s) : Huang J , Jones BJ , Kazlauskas RJ
Ref : Biochemistry , 54 :4330 , 2015
PubMedID: 26110207
Gene_locus related to this paper: nicta-SABP2

Title : Uncovering divergent evolution of alpha\/beta-hydrolases: a surprising residue substitution needed to convert hydroxynitrile lyase into an esterase - Nedrud_2014_Chem.Sci_5_4265
Author(s) : Nedrud DM , Lin H , Lopez G , Padhi SK , Legatt GA , Kazlauskas RJ
Ref : Chem Sci , 5 :4265 , 2014
Abstract :
PubMedSearch : Nedrud_2014_Chem.Sci_5_4265
PubMedID: 25346843
Gene_locus related to this paper: hevbr-hnl , nicta-SABP2

Title : Switching from an esterase to a hydroxynitrile lyase mechanism requires only two amino acid substitutions - Padhi_2010_Chem.Biol_17_863
Author(s) : Padhi SK , Fujii R , Legatt GA , Fossum SL , Berchtold R , Kazlauskas RJ
Ref : Chemical Biology , 17 :863 , 2010
Abstract :
PubMedSearch : Padhi_2010_Chem.Biol_17_863
PubMedID: 20797615
Gene_locus related to this paper: hevbr-hnl , nicta-SABP2

Title : Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity - Forouhar_2005_Proc.Natl.Acad.Sci.U.S.A_102_1773
Author(s) : Forouhar F , Yang Y , Kumar D , Chen Y , Fridman E , Park SW , Chiang Y , Acton TB , Montelione GT , Pichersky E , Klessig DF , Tong L
Ref : Proc Natl Acad Sci U S A , 102 :1773 , 2005
Abstract :
PubMedSearch : Forouhar_2005_Proc.Natl.Acad.Sci.U.S.A_102_1773
PubMedID: 15668381
Gene_locus related to this paper: nicta-SABP2

Title : High-affinity salicylic acid-binding protein 2 is required for plant innate immunity and has salicylic acid-stimulated lipase activity - Kumar_2003_Proc.Natl.Acad.Sci.U.S.A_100_16101
Author(s) : Kumar D , Klessig DF
Ref : Proc Natl Acad Sci U S A , 100 :16101 , 2003
Abstract :
PubMedSearch : Kumar_2003_Proc.Natl.Acad.Sci.U.S.A_100_16101
PubMedID: 14673096
Gene_locus related to this paper: nicta-SABP2