Methyl-salicylate
Salicylic Acid (SA) can be methylated or conjugated to glucose. SA is a natural beta hydroxy acid in plants (bark of the white willow and wintergreen leaves).SA is a critical signal for the activation of plant defense responses against pathogen infections. SABP2 binds SA with high affinity (Kd of 90 nM). SABP2 has strong esterase activity with methyl salicylate. SA has direct activity as an anti-inflammatory agent and acts as a topical antibacterial agent due to its ability to promote exfoliation. Methyl 2-hydroxybenzoate is found in beverages. Methyl 2-hydroxybenzoate is present in white wine, tea, porcini mushroom Boletus edulis, Bourbon vanilla, clary sage, red sage and fruits including cherry, apple, raspberry, papaya and plum. Methyl 2-hydroxybenzoate is found in leaves of Gaultheria procumbens (wintergreen). Methyl 2-hydroxybenzoate is a flavouring agent.
General
Type : Plant hormone, Natural, Aryl ester, Salicylic, Benzoate
Chemical_Nomenclature : methyl 2-hydroxybenzoate
Canonical SMILES : COC(=O)C1=CC=CC=C1O
InChI : InChI=1S\/C8H8O3\/c1-11-8(10)6-4-2-3-5-7(6)9\/h2-5,9H,1H3
InChIKey : OSWPMRLSEDHDFF-UHFFFAOYSA-N
Other name(s) : MeSA || Methyl salicylate || Methyl 2-hydroxybenzoate || Methyl-2-hydroxybenzoate || Gaultheria oil || Wintergreen oil || Betula oil
MW : 152.14
Formula : C8H8O3
CAS_number : 119-36-8
PubChem : 4133
UniChem : OSWPMRLSEDHDFF-UHFFFAOYSA-N
Wikipedia : Methyl_salicylate
Target
Structures : No structure
Families : Hydroxynitrile_lyase, 6_AlphaBeta_hydrolase
References (5)
| Title : A methyl esterase 1 (PvMES1) promotes the salicylic acid pathway and enhances Fusarium wilt resistance in common beans - Xue_2021_Theor.Appl.Genet__ |
| Author(s) : Xue R , Feng M , Chen J , Ge W , Blair MW |
| Ref : Theor Appl Genet , : , 2021 |
| Abstract : |
| PubMedSearch : Xue_2021_Theor.Appl.Genet__ |
| PubMedID: 34128089 |
| Gene_locus related to this paper: phavu-v7cf29 |
| Title : An enzyme from Auricularia auricula-judae combining both benzoyl and cinnamoyl esterase activity - Haase-Aschoff_2013_Process.Biochem_48_1872 |
| Author(s) : Haase-Aschoff P , Linke D , Nimtz M , Popper L , Berger RG |
| Ref : Process Biochemistry , 48 :1872 , 2013 |
| Abstract : |
| PubMedSearch : Haase-Aschoff_2013_Process.Biochem_48_1872 |
| PubMedID: |
| Gene_locus related to this paper: aurst-EJD51015 |
| Title : Inactive methyl indole-3-acetic acid ester can be hydrolyzed and activated by several esterases belonging to the AtMES esterase family of Arabidopsis - Yang_2008_Plant.Physiol_147_1034 |
| Author(s) : Yang Y , Xu R , Ma CJ , Vlot AC , Klessig DF , Pichersky E |
| Ref : Plant Physiol , 147 :1034 , 2008 |
| Abstract : |
| PubMedSearch : Yang_2008_Plant.Physiol_147_1034 |
| PubMedID: 18467465 |
| Gene_locus related to this paper: arath-MES17 , arath-AT4G16690 , arath-AT4G37150 , arath-MES6 , arath-MES7 , arath-MES3 , arath-MES1 , arath-MES18 , arath-MES10 , arath-MES19 |
| Title : Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity - Forouhar_2005_Proc.Natl.Acad.Sci.U.S.A_102_1773 |
| Author(s) : Forouhar F , Yang Y , Kumar D , Chen Y , Fridman E , Park SW , Chiang Y , Acton TB , Montelione GT , Pichersky E , Klessig DF , Tong L |
| Ref : Proc Natl Acad Sci U S A , 102 :1773 , 2005 |
| Abstract : |
| PubMedSearch : Forouhar_2005_Proc.Natl.Acad.Sci.U.S.A_102_1773 |
| PubMedID: 15668381 |
| Gene_locus related to this paper: nicta-SABP2 |