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sphmc-SpL

Sphingopyxis macrogoltabida (Sphingomonas macrogoltabidus) Sphingomonas sp. HXN-200 intracellular lipase

Comment

Other strains: Sphingomonas sp. HXN-200 lipase for amide synthesis via aminolysis of ester or acid. || Amide formation of (hetero)aromatic esters and primary amines in buffer catalyzed by serine hydrolases: An Asp next to Ser of the catalytic triad of serine hydrolases is crucial for activity. Biocatalytic Heteroaromatic Amide Formation in Water Enabled by a Catalytic Tetrad and Two Access Tunnels

Relationship

Family : Hormone-sensitive_lipase_like

Block : H

Position in NCBI Life Tree : Sphingopyxis macrogoltabida

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Proteobacteria N E > Alphaproteobacteria N E > Sphingomonadales N E > Sphingomonadaceae N E > Sphingopyxis N E > Sphingopyxis macrogoltabida N E

Molecular evidence

Database

Sequence

Peptide

MTDSTTHYTR PDVAAFLAFL NAQEGPKMEE MPPAGAREMM RVMGQLADVP RGEIAKVEDR MIPGPDGDIP IRLYDNRPDR EAGPVMVFYH GGGWVIGDLE THDPYCAEAA RILDMPVIAI DYRLAPEHPF PAAPIDCEAA TRWVADNIAC TGLVLSGDSA GGNLTIVTAL ALRDEPAAKP VIAIHPIYPA VTTHNDWQSY RDFGEGHLLT EGSMTWFGNH YAADPADRRA APIDFPADGL PPTLLITASL DPLRDQGRAY AAKLIEAGVP TTYREAKGTI HGYICLAQGI PSAKDDIRGA LTVLKAIVAE ATGAA

References (2)

Title : Biocatalytic Heteroaromatic Amide Formation in Water Enabled by a Catalytic Tetrad and Two Access Tunnels - Zukic_2024_ACS.Catal_14_8913
Author(s) : Zukic E , Mokos D , Weber M , Stix N , Ditrich K , Ferrario V , Muller H , Willrodt C , Gruber K , Daniel B , Kroutil W
Ref : ACS Catal , 14 :8913 , 2024
Abstract :
PubMedSearch : Zukic_2024_ACS.Catal_14_8913
PubMedID: 38868102
Gene_locus related to this paper: sphmc-SpL

Title : Amide Synthesis via Aminolysis of Ester or Acid with an Intracellular Lipase - Zeng_2018_ACS.Catal_8_8856
Author(s) : Zeng S , Liu J , Anankanbil S , Chen M , Guo Z , Adams JP , Snajdrova R , Li Z
Ref : ACS Catal , 8 :8856 , 2018
Abstract :
PubMedSearch : Zeng_2018_ACS.Catal_8_8856
PubMedID:
Gene_locus related to this paper: sphmc-SpL