1. Home
  2. Gene Locus
  3. toxgo-a0a125yz56

toxgo-a0a125yz56

Toxoplasma gondii ASH4 TgME49_262290 hydrolase TgASH4

Comment

preference for short acyl substrate. No depalmitoylase activity

Relationship

Family : ABHD17-depalmitoylase

Block : X

Position in NCBI Life Tree : Toxoplasma gondii

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Alveolata N E > Apicomplexa N E > Conoidasida N E > Coccidia N E > Eucoccidiorida N E > Eimeriorina N E > Sarcocystidae N E > Toxoplasma N E > Toxoplasma gondii N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MGNALKRMVF QPPSPPTYEC DASFIWLTTR RRQRIPAFFI DIGASLTIIF SHGNAEDIGM VIEYFKEVSR LWNCNFFVYD YVGYGHSTGK PSEQGVYDSV EAAFEYLTLQ LGLPASSIVV YGRSLGTGAS CHLASRHRLA GMILQSGLTS IHRVGLNTRF SLPGDMFCNI DKIGRVDCPV FIIHGTKDEI VPVHHGMELY NRCPLSVTPY WVEGGGHNNL ELLGRRTFYE NVARFLKFVR ARETPGVRSG PLSSTARLVR

References (3)

Title : Toxoplasma gondii serine hydrolases regulate parasite lipid mobilization during growth and replication within the host - Onguka_2021_Cell.Chem.Biol__
Author(s) : Onguka O , Babin BM , Lakemeyer M , Foe IT , Amara N , Terrell SM , Lum KM , Cieplak P , Niphakis MJ , Long JZ , Bogyo M
Ref : Cell Chemical Biology , : , 2021
Abstract :
PubMedSearch : Onguka_2021_Cell.Chem.Biol__
PubMedID: 34043961
Gene_locus related to this paper: toxgo-TgASH3 , toxgo-TgASH2 , toxgo-s4ug63 , toxgo-a0a125yz56

Title : The Toxoplasma gondii Active Serine Hydrolase 4 Regulates Parasite Division and Intravacuolar Parasite Architecture - Foe_2018_mSphere_3_
Author(s) : Foe IT , Onguka O , Amberg-Johnson K , Garner RM , Amara N , Beatty W , Yeh E , Bogyo M
Ref : mSphere , 3 : , 2018
Abstract :
PubMedSearch : Foe_2018_mSphere_3_
PubMedID: 30232166
Gene_locus related to this paper: toxgo-a0a125yz56

Title : Characterization of a serine hydrolase targeted by acyl-protein thioesterase inhibitors in Toxoplasma gondii - Kemp_2013_J.Biol.Chem_288_27002
Author(s) : Kemp LE , Rusch M , Adibekian A , Bullen HE , Graindorge A , Freymond C , Rottmann M , Braun-Breton C , Baumeister S , Porfetye AT , Vetter IR , Hedberg C , Soldati-Favre D
Ref : Journal of Biological Chemistry , 288 :27002 , 2013
Abstract :
PubMedSearch : Kemp_2013_J.Biol.Chem_288_27002
PubMedID: 23913689
Gene_locus related to this paper: toxgo-TgASH3 , toxgo-TgASH2 , toxgo-s8en43 , toxgo-s4ug63 , toxgo-a0a125yz56