Gene_Locus Report

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Gene_locus Report for: hetga-g5b7v3

Heterocephalus glaber (Naked mole rat). Abhydrolase domain-containing protein 8

Relationship
Family|ABHD8
Block| X
Position in NCBI Life Tree|Heterocephalus glaber
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Sarcopterygii: N E > Dipnotetrapodomorpha: N E > Tetrapoda: N E > Amniota: N E > Mammalia: N E > Theria: N E > Eutheria: N E > Boreoeutheria: N E > Euarchontoglires: N E > Glires: N E > Rodentia: N E > Hystricomorpha: N E > Bathyergidae: N E > Heterocephalus: N E > Heterocephalus glaber: N E


Molecular evidence
Database
No mutation
No structure
No kinetic





No Substrate
No inhibitor
1 Genbank : JH168822
1 UniProt : G5B7V3
1 UniProt : G5B7V3
1 Interpro : G5B7V3
1 Prodom : G5B7V3
1 Pfam : G5B7V3
1 PIRSF : G5B7V3
1 SUPERFAM : G5B7V3
Sequence
Graphical view for this peptide sequence: hetga-g5b7v3
Colored MSA for ABHD8 (raw)
MLTGVTEGFLCCLLGSPPNAVGPLESVESGDGYTFVEVKPGRVLRVKHAG
PASAPSPPSPPDTAQGGRAGLVRCQRRITVYRNGRLLVGGGGRRRRARRP
KRTIHIDCERRVTSCKGAQADVVLFFIHGVGGSLAIWKAQLDFFVRLGYE
VVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFKRYAKKRNVLIGHSYG
VSFCTFLAHEYPDLVHKVIMINGGGPTALEPSICSIFNMPACVLHCLSPC
LAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVY
HAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIDEGSHMVMLEC
PETVNTLLHEFLLWEPEPSPRALPEPQPTPTEEE
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MLTGVTEGFLCCLLGSPPNAVGPLESVESGDGYTFVEVKPGRVLRVKHAG
PASAPSPPSPPDTAQGGRAGLVRCQRRITVYRNGRLLVGGGGRRRRARRP
KRTIHIDCERRVTSCKGAQADVVLFFIHGVGGSLAIWKAQLDFFVRLGYE
VVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFKRYAKKRNVLIGHSYG
VSFCTFLAHEYPDLVHKVIMINGGGPTALEPSICSIFNMPACVLHCLSPC
LAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVY
HAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIDEGSHMVMLEC
PETVNTLLHEFLLWEPEPSPRALPEPQPTPTEEE


Reference
    Title: Genome sequencing reveals insights into physiology and longevity of the naked mole rat
    Kim EB, Fang X, Fushan AA, Huang Z, Lobanov AV, Han L, Marino SM, Sun X, Turanov AA and Gladyshev VN <26 more author(s)>
    Ref: Nature, 479:223, 2011 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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