1. Home
  2. Inhibitor
  3. 1,3-Dibenzylurea

1,3-Dibenzylurea

General

Type : Natural,Urea derivative

Chemical_Nomenclature : 1,3-dibenzylurea

Canonical SMILES : C1=CC=C(C=C1)CNC(=O)NCC2=CC=CC=C2

InChI : InChI=1S\/C15H16N2O\/c18-15(16-11-13-7-3-1-4-8-13)17-12-14-9-5-2-6-10-14\/h1-10H,11-12H2,(H2,16,17,18)

InChIKey : KATOLVAXCGIBLO-UHFFFAOYSA-N

Other name(s) : N,N'-Dibenzylurea,1466-67-7,Sym-Dibenzylurea,Urea, N,N'-bis(phenylmethyl)-,1,3-dibenzyl urea

MW : 240.30

Formula : C15H16N2O

CAS_number :

PubChem : 72889

UniChem : KATOLVAXCGIBLO-UHFFFAOYSA-N

Target

Families : 1,3-Dibenzylurea ligand of proteins in family
Epoxide_hydrolase

References (4)

Title : Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales - Kitamura_2017_PLoS.One_12_e0176571
Author(s) : Kitamura S , Morisseau C , Harris TR , Inceoglu B , Hammock BD
Ref : PLoS ONE , 12 :e0176571 , 2017
Abstract : Kitamura_2017_PLoS.One_12_e0176571
ESTHER : Kitamura_2017_PLoS.One_12_e0176571
PubMedSearch : Kitamura_2017_PLoS.One_12_e0176571
PubMedID: 28472063

Title : Potent natural soluble epoxide hydrolase inhibitors from Pentadiplandra brazzeana baillon: synthesis, quantification, and measurement of biological activities in vitro and in vivo - Kitamura_2015_PLoS.One_10_e0117438
Author(s) : Kitamura S , Morisseau C , Inceoglu B , Kamita SG , De Nicola GR , Nyegue M , Hammock BD
Ref : PLoS ONE , 10 :e0117438 , 2015
Abstract : Kitamura_2015_PLoS.One_10_e0117438
ESTHER : Kitamura_2015_PLoS.One_10_e0117438
PubMedSearch : Kitamura_2015_PLoS.One_10_e0117438
PubMedID: 25659109

Title : Rare dipeptide and urea derivatives from roots of Moringa oleifera as potential anti-inflammatory and antinociceptive agents - Sashidhara_2009_Eur.J.Med.Chem_44_432
Author(s) : Sashidhara KV , Rosaiah JN , Tyagi E , Shukla R , Raghubir R , Rajendran SM
Ref : Eur Journal of Medicinal Chemistry , 44 :432 , 2009
Abstract : Sashidhara_2009_Eur.J.Med.Chem_44_432
ESTHER : Sashidhara_2009_Eur.J.Med.Chem_44_432
PubMedSearch : Sashidhara_2009_Eur.J.Med.Chem_44_432
PubMedID: 18243423

Title : Urea derivatives from Pentadiplandra brazzeana - Tsopmo_1999_J.Nat.Prod_62_1435
Author(s) : Tsopmo A , Ngnokam D , Ngamga D , Ayafor JF , Sterner O
Ref : Journal of Natural Products , 62 :1435 , 1999
Abstract : Tsopmo_1999_J.Nat.Prod_62_1435
ESTHER : Tsopmo_1999_J.Nat.Prod_62_1435
PubMedSearch : Tsopmo_1999_J.Nat.Prod_62_1435
PubMedID: 10543911 
Array
(
    [id] => 2997
    [inhibitor] => 1,3-Dibenzylurea
    [type] => Array
        (
            [0] => Natural
            [1] => Urea derivative
        )

    [other_name] => Array
        (
            [0] => N,N'-Dibenzylurea
            [1] => 1466-67-7
            [2] => Sym-Dibenzylurea
            [3] => Urea, N,N'-bis(phenylmethyl)-
            [4] => 1,3-dibenzyl urea
        )

    [chemical_nomenclature] => 1,3-dibenzylurea
    [formula] => C15H16N2O
    [cas_number] => 
    [mw] => 240.30
    [pick_me_to_call] => display_script
    [kinetic_parameter] => 
    [paper] => Kitamura_2017_PLoS.One_12_e0176571 || Kitamura_2015_PLoS.One_10_e0117438 || Sashidhara_2009_Eur.J.Med.Chem_44_432 || Tsopmo_1999_J.Nat.Prod_62_1435
    [comment] => 
    [gene_locus] => 
    [kin_inhibitor] => 
    [cid] => 72889
    [family] => Epoxide_hydrolase
    [inchikey] => KATOLVAXCGIBLO-UHFFFAOYSA-N
    [canonicalsmiles] => C1=CC=C(C=C1)CNC(=O)NCC2=CC=CC=C2
    [inchi] => InChI=1S\/C15H16N2O\/c18-15(16-11-13-7-3-1-4-8-13)17-12-14-9-5-2-6-10-14\/h1-10H,11-12H2,(H2,16,17,18)
    [wikipedia] => 
    [iupharlig] => 
    [structure] => 
    [substrate] => 
    [interact_gene_locus] => 
    [mutation] => 
    [comment2] => 
    [extoxnet] => 
    [news] => 
    [theoretical_model] => 
)