4-Phenylchalcone-oxide
General
Type : Epoxide
Chemical_Nomenclature : phenyl-[3-(4-phenylphenyl)oxiran-2-yl]methanone
Canonical SMILES : C1=CC=C(C=C1)C2=CC=C(C=C2)C3C(O3)C(=O)C4=CC=CC=C4
InChI : InChI=1S\/C21H16O2\/c22-19(17-9-5-2-6-10-17)21-20(23-21)18-13-11-16(12-14-18)15-7-3-1-4-8-15\/h1-14,20-21H
InChIKey : WCVMKDUZFGWJAF-UHFFFAOYSA-N
Other name(s) : CCRIS 2240, AC1L44WC, SCHEMBL655373, 4-Phenylchalcone Oxide, 4-PCO
MW : 300.35
Formula : C21H16O2
CAS_number : 82389-34-2
PubChem : 150734
UniChem : WCVMKDUZFGWJAF-UHFFFAOYSA-N
Target
Families : 4-Phenylchalcone-oxide ligand of proteins in family
Epoxide_hydrolase
Protein :
human-EPHX2
References (5)
| Title : Role of epoxy-fatty acids and epoxide hydrolases in the pathology of neuro-inflammation - Kodani_2019_Biochimie_159_59 |
| Author(s) : Kodani SD , Morisseau C |
| Ref : Biochimie , 159 :59 , 2019 |
| PubMedID: 30716359 |
| Title : Inhibition of soluble epoxide hydrolase after cardiac arrest\/cardiopulmonary resuscitation induces a neuroprotective phenotype in activated microglia and improves neuronal survival - Wang_2013_J.Cereb.Blood.Flow.Metab_33_1574 |
| Author(s) : Wang J , Fujiyoshi T , Kosaka Y , Raybuck JD , Lattal KM , Ikeda M , Herson PS , Koerner IP |
| Ref : Journal of Cerebral Blood Flow & Metabolism , 33 :1574 , 2013 |
| PubMedID: 23820647 |
| Title : 14,15-Dihydroxyeicosatrienoic acid relaxes bovine coronary arteries by activation of K(Ca) channels - Campbell_2002_Am.J.Physiol.Heart.Circ.Physiol_282_H1656 |
| Author(s) : Campbell WB , Deeter C , Gauthier KM , Ingraham RH , Falck JR , Li PL |
| Ref : American Journal of Physiology Heart Circ Physiol , 282 :H1656 , 2002 |
| PubMedID: 11959628 |
| Title : Leukotoxin-diol: a putative toxic mediator involved in acute respiratory distress syndrome - Zheng_2001_Am.J.Respir.Cell.Mol.Biol_25_434 |
| Author(s) : Zheng J , Plopper CG , Lakritz J , Storms DH , Hammock BD |
| Ref : American Journal of Respiratory Cellular & Molecular Biology , 25 :434 , 2001 |
| PubMedID: 11694448 |
| Title : Epoxide hydrolases regulate epoxyeicosatrienoic acid incorporation into coronary endothelial phospholipids - Weintraub_1999_Am.J.Physiol_277_H2098 |
| Author(s) : Weintraub NL , Fang X , Kaduce TL , VanRollins M , Chatterjee P , Spector AA |
| Ref : American Journal of Physiology , 277 :H2098 , 1999 |
| PubMedID: 10564166 |