A-262-Nerve-agent
Novichok (newcomer/ newbie/ novice, beginner/) is a series of binary chemical weapons developed by the Soviet Union and Russia between 1971 and 1993. Mirzayanov provided the first description of these agents but are somewhat different from the structures identified later. A-262 is not specifically listed in the Annex on Chemicals of the Chemical Weapons Convention, and falls outside the general definitions covering other Novichok agents, even though it has a chemical structure similar to that of both A-232 (the example compound for schedule 1.A.14) and A-242 (the example compound for schedule 1.A.15)
General
Type : Organophosphate, Chemical Warfare Agent, Novichok
Chemical_Nomenclature : 1,1,3,3-tetraethyl-2-[fluoro(methoxy)phosphoryl]guanidine
Canonical SMILES : CCN(CC)C(=NP(=O)(OC)F)N(CC)CC
InChI : InChI=1S\/C10H23FN3O2P\/c1-6-13(7-2)10(14(8-3)9-4)12-17(11,15)16-5\/h6-9H2,1-5H3
InChIKey : AEQJLRXTEIZQBQ-UHFFFAOYSA-N
Other name(s) : A-262 nerve agent || A-262 || A262 || MCL38N4DHF || SCHEMBL23866424 || DTXSID801336561
MW : 267.28
Formula : C10H23FN3O2P
CAS_number :
PubChem : 149628685
UniChem : AEQJLRXTEIZQBQ-UHFFFAOYSA-N
Wikipedia : Novichok_agent
Target
Families : A-262-Nerve-agent ligand of proteins in family
ACHE
Protein :
human-ACHE
References (4)
| Title : In vitro comparison of the acetylcholinesterase inhibition caused by V- and A-series nerve agents' surrogates - Kitagawa_2023_Chem.Biol.Interact_14ChEPon_110678 |
| Author(s) : Kitagawa DAS , Dos Santos MC , Kuca K , Franca TCC , Cavalcante SFA |
| Ref : Chemico-Biological Interactions , 383 :110678 , 2023 |
| Abstract : |
| PubMedSearch : Kitagawa_2023_Chem.Biol.Interact_14ChEPon_110678 |
| PubMedID: 37595776 |
| Title : Are the current commercially available oximes capable of reactivating acetylcholinesterase inhibited by the nerve agents of the A-series? - Santos_2022_Arch.Toxicol__ |
| Author(s) : Santos MC , Botelho FD , Goncalves AS , Kitagawa DAS , Borges CVN , Carvalho-Silva T , Bernardo LB , Ferreira CN , Rodrigues RB , Ferreira Neto DC , Nepovimova E , Kuca K , LaPlante SR , Lima ALS , Franca TCC , Cavalcante SFA |
| Ref : Archives of Toxicology , : , 2022 |
| Abstract : |
| PubMedSearch : Santos_2022_Arch.Toxicol__ |
| PubMedID: 35666269 |
| Title : Theoretical assessment of the performances of commercial oximes on the reactivation of acetylcholinesterase inhibited by the nerve agent A-242 (novichok) - Santos_2022_Food.Chem.Toxicol__113084 |
| Author(s) : Santos MC , Botelho FD , Goncalves AS , Kuca K , Nepovimova E , Cavalcante SFA , Lima ALS , Franca TCC |
| Ref : Food & Chemical Toxicology , :113084 , 2022 |
| Abstract : |
| PubMedSearch : Santos_2022_Food.Chem.Toxicol__113084 |
| PubMedID: 35489467 |
| Title : Novichok nerve agents banned by chemical-weapons treaty - |
| Author(s) : Castelvecchi D |
| Ref : Nature , : , 2019 |
| PubMedID: 33244185 |