Acetaminophen

Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide. It is also used for its antipyretic effects, helping to reduce fever.

General

Type : Not AlphaBeta Hydrolase target, Drug, Multitarget

Chemical_Nomenclature : N-(4-hydroxyphenyl)acetamide

Canonical SMILES : CC(=O)NC1=CC=C(C=C1)O

InChI : InChI=1S\/C8H9NO2\/c1-6(10)9-7-2-4-8(11)5-3-7\/h2-5,11H,1H3,(H,9,10)

InChIKey : RZVAJINKPMORJF-UHFFFAOYSA-N

Other name(s) : Paracetamol  ||  Doliprane  ||  Injectapap  ||  Acenol  ||  Biocetamol  ||  Febridol


MW : 151.16\

Formula : C8H9NO2

CAS_number : 103-90-2

PubChem : 1983

UniChem : RZVAJINKPMORJF-UHFFFAOYSA-N

Target

Families : Acetaminophen ligand of proteins in family
Lipase_3

Protein :
human-DAGLA

References (1)

Title : Acetaminophen inhibits diacylglycerol lipase synthesis of 2-arachidonoyl glycerol: Implications for nociception - Dvorakova_2025_Cell.Rep.Med__102139
Author(s) : Dvorakova M , Bosquez-Berger T , Billingsley J , Murataeva N , Woodward T , Leishman E , Zimmowitch A , Gibson A , Wager-Miller J , Cai R , Cai S , Ware T , Hsu KL , Li Y , Bradshaw H , Mackie K , Straiker A
Ref : Cell Rep Med , :102139 , 2025
Abstract :
PubMedSearch : Dvorakova_2025_Cell.Rep.Med__102139
PubMedID: 40381619