Aminoethyl-methyl-phenyl-triazole-carboxamide-cpd1D
IC50 eleelAChE 0.590 +/- 0.02 microM horse BACE1 9.85 +/- 1.93 microM
General
Type : Triazol, Carboxamide, Multitarget, BACE1-inhibitor
Chemical_Nomenclature : N-(2-aminoethyl)-5-methyl-1-phenyl-1H-1,2,3-triazole-4-carboxamide hydrochloride
Canonical SMILES : C1(=C([N](N=N1)C2=CC=CC=C2)C)C(NCCN)=O
InChI : 1S\/C12H15N5O\/c1-9-11(12(18)14-8-7-13)15-16-17(9)10-5-3-2-4-6-10\/h2-6H,7-8,13H2,1H3,(H,14,18)
InChIKey : KVYFDUBJJWWFOR-UHFFFAOYSA-N
Other name(s) : Compound 1D
Target
Families : Aminoethyl-methyl-phenyl-triazole-carboxamide-cpd1D ligand of proteins in family
ACHE
References (1)
| Title : Design, Synthesis, and Biological Evaluation of Novel Acetylcholinesterase and beta-Secretase 1 Inhibitors - Drozdowska_2026_Int.J.Mol.Sci_27_1008 |
| Author(s) : Drozdowska D , Pawelski D , Wrobel-Talalaj A , Plonska-Brzezinska M , Kolesinska B , Lazny R , Seroka B , Parzych C , Ratkiewicz A |
| Ref : Int J Mol Sci , 27 :1008 , 2026 |
| Abstract : |
| PubMedSearch : Drozdowska_2026_Int.J.Mol.Sci_27_1008 |
| PubMedID: 41596653 |