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Azanyl-oxidanylidene-(sulfoamino)phosphanium-A1INF

Adduct covalently linked to active serine

General

Type : Sulfur Compound, Organophosphate

Chemical_Nomenclature :

Canonical SMILES : N[P+](=O)NS(=O)(=O)O

InChI : InChI=1S\/H3N2O4PS\/c1-7(3)2-8(4,5)6\/h(H3-,1,2,3,4,5,6)\/p+1

InChIKey : UGZLMCWNUKYQNY-UHFFFAOYSA-O

Other name(s) :

MW : 159.082

Formula : H4N2O4PS

CAS_number :

PubChem :

UniChem : UGZLMCWNUKYQNY-UHFFFAOYSA-O

Target

Families : Azanyl-oxidanylidene-(sulfoamino)phosphanium-A1INF ligand of proteins in family
DPP4N_Peptidase_S9

Structure :
9GON 9GOH

Protein :
human-DPP9 human-DPP4

References (1)

Title : Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors - Sewald_2025_Nat.Commun_16_3208
Author(s) : Sewald L , Tabak WWA , Fehr L , Zolg S , Najdzion M , Verhoef CJA , Podlesainski D , Geiss-Friedlander R , Lammens A , Kaschani F , Hellerschmied D , Huber R , Kaiser M
Ref : Nat Commun , 16 :3208 , 2025
Abstract :
PubMedSearch : Sewald_2025_Nat.Commun_16_3208
PubMedID: 40180908
Gene_locus related to this paper: human-DPP4 , human-DPP8 , human-DPP9