Benzothiophene-3-boronic-acid
IC50 FphE 0.051 +/- 0.004 microM
General
Type : Sulfur Compound, Thiophen, Boron compound
Chemical_Nomenclature : 1-benzothiophen-3-ylboronic acid
Canonical SMILES : B(C1=CSC2=CC=CC=C12)(O)O
InChI : InChI=1S\/C8H7BO2S\/c10-9(11)7-5-12-8-4-2-1-3-6(7)8\/h1-5,10-11H
InChIKey : QVANIYYVZZLQJP-UHFFFAOYSA-N
Other name(s) : (1-benzothiophen-3-yl)boronic acid || 808-005-7 || Benzothiophene-3-boronic acid || 1-benzothiophen-3-ylboronic acid || Compound Z27 || CHEMBL342173 || SCHEMBL9024
MW : 178.02
Formula : C8H7BO2S
CAS_number : 113893-08-6
PubChem : 2776344
UniChem : QVANIYYVZZLQJP-UHFFFAOYSA-N
Target
Families : Benzothiophene-3-boronic-acid ligand of proteins in family
6_AlphaBeta_hydrolase
Structure :
8UGM
Protein :
staau-SA2367
References (1)
| Title : Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation - Upadhyay_2025_Nat.Commun_16_5046 |
| Author(s) : Upadhyay T , Woods EC , Dela Ahator S , Julin K , Faucher FF , Uddin MJ , Hollander MJ , Pedowitz NJ , Abegg D , Hammond I , Eke IE , Wang S , Chen S , Bennett JM , Jo J , Lentz CS , Adibekian A , Fellner M , Bogyo M |
| Ref : Nat Commun , 16 :5046 , 2025 |
| Abstract : |
| PubMedSearch : Upadhyay_2025_Nat.Commun_16_5046 |
| PubMedID: 40447595 |
| Gene_locus related to this paper: staau-MW0741 , staau-SA2367 , staep-SE2095 |