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Thiophen

General

Thiophene is a heterocyclic compound with the formula C4H4S. Consisting of a planar five-membered ring. They can be used as building block in sythesis
Inhibitor Main targeted enzyme families Type Structure
Thiophen-amino-chromen-2-one-Cpd6h ACHE BCHE Chromen Sulfur Compound Thiophen GSK-3 kinase inhibitor anti-tau-aggregation Multitarget
Methyl-thienyl-ethenyl-phenol-cpd135 BCHE Sulfur Compound Thiophen
Canagliflozin Drug Multitarget Sodium-glucose cotransporter 2 Thiophen Sulfur Compound Glycoside
Pyrazoline-Thiazole-Cpd3f Pyrazole Pyrazoline Thiophen Sulfur Compound Thiazole pNP Dimethoxyphenyl
Pyrazoline-Thiazole-Cpd3g Pyrazole Pyrazoline Thiophen Sulfur Compound Thiazole Dimethoxyphenyl Cyanide
Thieno-Oxazepine-Cpd14 ACHE Multitarget Azepane Sulfur Compound Thiophen
Benzothiophene-3-boronic-acid Sulfur Compound Thiophen Boron compound
Methylthiophen-tacrine-Amine-cpd5m ACHE BCHE Multitarget NMDA-Ligand Derivative of Tacrine Acridine Sulfur Compound Thiophen
Resveratrol-carbamate-cpd7 BCHE Carbamate Sulfur Compound Multitarget Antioxidant Thiophen
Resveratrol-carbamate-cpd13 BCHE Carbamate Sulfur Compound Multitarget Antioxidant Thiophen
Resveratrol-carbamate-cpd6 BCHE Carbamate Sulfur Compound Multitarget Antioxidant Thiophen
Resveratrol-carbamate-cpdF BCHE Carbamate Sulfur Compound Multitarget Antioxidant Thiophen Morpholine
Tricyclic-cyclohepta-thiophene-cpd9 ACHE Sulfur Compound Oxazine Thiophen
Duloxetine BCHE Drug Multitarget Sodium:neurotransmitter symporter Naphthalen Sulfur Compound Thiophen
Nitrophenyl-thiophen-morpholinyl-phenyl-pyrazoline-2l ACHE Sulfur Compound Pyrazole Morpholine Thiophen Pyrazoline
Trifluoromethyl-thiophene-boronic-acid 6_AlphaBeta_hydrolase CarbLipBact_1 Trifluoro Boron compound Sulfur Compound Thiophen
Homocysteine-thiolactone ACHE Valacyclovir-hydrolase Carb_B_Chordata Natural Sulfur Compound Not AlphaBeta Hydrolase target Thiophen
Fluoropezil ACHE Multitarget Derivative of Donepezil Sulfur Compound anti-tau-aggregation Antioxidant Thiophen
N-methyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxamide Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Carboxamide Thiophen
4,5-Dihydronaphtho[1,2-b]thiophene-2-carboxylic-acid Pectinacetylesterase-Notum Thiophen Sulfur Compound
Methyl-4H-thieno[3,2-c]chromene-2-carboxylic-acid Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Chromen Thiophen
CHEMBL3233609-S0K-3WKD Epoxide_hydrolase Carboxamide Sulfur Compound Morpholine Thiophen
CHEMBL4644372 Epoxide_hydrolase LTA4-hydrolase-inhibitor Multitarget Sulfur Compound Piperidine Thiophen
CHEMBL1375713 Epoxide_hydrolase Sulfur Compound Thiophen
CHEMBL4465514 Epoxide_hydrolase Piperidine Carboxamide Sulfur Compound Thiophen
I3-AG85 A85-Mycolyl-transferase Cyanide Sulfur Compound Thiophen
ZINC02141756 Carb_B_Chordata Trifluoro Sulfur Compound Thiophen Hydrazinylidene
Quinazolin-carbamate-2p BCHE Quinazoline Carbamate Sulfur Compound Thiophen
Thiophen-amino-chromen-2-one-Cpd6h ACHE BCHE Chromen Sulfur compound Thiophen GSK-3 kinase inhibitor anti-tau-aggregation Multitarget
Methyl-thienyl-ethenyl-phenol-cpd135 BCHE Sulfur compound Thiophen
Canagliflozin Drug Multitarget Sodium-glucose cotransporter 2 Thiophen Sulfur compound Glycoside
Pyrazoline-Thiazole-Cpd3f Pyrazole Pyrazoline Thiophen Sulfur compound Thiazole pNP Dimethoxyphenyl
Pyrazoline-Thiazole-Cpd3g Pyrazole Pyrazoline Thiophen Sulfur compound Thiazole Dimethoxyphenyl Cyanide
Thieno-Oxazepine-Cpd14 ACHE Multitarget Azepane Sulfur compound Thiophen
Benzothiophene-3-boronic-acid Sulfur compound Thiophen Boron compound
Methylthiophen-tacrine-Amine-cpd5m ACHE BCHE Multitarget NMDA-Ligand Derivative of Tacrine Acridine Sulfur compound Thiophen
Resveratrol-carbamate-cpd7 BCHE Carbamate Sulfur compound Multitarget Antioxidant Thiophen
Resveratrol-carbamate-cpd13 BCHE Carbamate Sulfur compound Multitarget Antioxidant Thiophen
Resveratrol-carbamate-cpd6 BCHE Carbamate Sulfur compound Multitarget Antioxidant Thiophen
Resveratrol-carbamate-cpdF BCHE Carbamate Sulfur compound Multitarget Antioxidant Thiophen Morpholine
Tricyclic-cyclohepta-thiophene-cpd9 ACHE Sulfur compound Oxazine Thiophen
Duloxetine BCHE Drug Multitarget Sodium:neurotransmitter symporter Naphthalen Sulfur compound Thiophen
Nitrophenyl-thiophen-morpholinyl-phenyl-pyrazoline-2l ACHE Sulfur compound Pyrazole Morpholine Thiophen Pyrazoline
Trifluoromethyl-thiophene-boronic-acid 6_AlphaBeta_hydrolase CarbLipBact_1 Trifluoro Boron compound Sulfur compound Thiophen
Homocysteine-thiolactone ACHE Valacyclovir-hydrolase Carb_B_Chordata Natural Sulfur compound Not AlphaBeta Hydrolase target Thiophen
Fluoropezil ACHE Multitarget Derivative of Donepezil Sulfur compound anti-tau-aggregation Antioxidant Thiophen
N-methyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxamide Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur compound Carboxamide Thiophen
4,5-Dihydronaphtho[1,2-b]thiophene-2-carboxylic-acid Pectinacetylesterase-Notum Thiophen Sulfur compound
Methyl-4H-thieno[3,2-c]chromene-2-carboxylic-acid Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur compound Chromen Thiophen
CHEMBL3233609-S0K-3WKD Epoxide_hydrolase Carboxamide Sulfur compound Morpholine Thiophen
CHEMBL4644372 Epoxide_hydrolase LTA4-hydrolase-inhibitor Multitarget Sulfur compound Piperidine Thiophen
CHEMBL1375713 Epoxide_hydrolase Sulfur compound Thiophen
CHEMBL4465514 Epoxide_hydrolase Piperidine Carboxamide Sulfur compound Thiophen
I3-AG85 A85-Mycolyl-transferase Cyanide Sulfur compound Thiophen
ZINC02141756 Carb_B_Chordata Trifluoro Sulfur compound Thiophen Hydrazinylidene
Quinazolin-carbamate-2p BCHE Quinazoline Carbamate Sulfur compound Thiophen
Thiophen-amino-chromen-2-one-Cpd6h ACHE BCHE Chromen Sulfur compound Thiophen GSK-3 kinase inhibitor anti-tau-aggregation Multitarget
Methyl-thienyl-ethenyl-phenol-cpd135 BCHE Sulfur compound Thiophen
Canagliflozin Drug Multitarget Sodium-glucose cotransporter 2 Thiophen Sulfur compound Glycoside
Pyrazoline-Thiazole-Cpd3f Pyrazole Pyrazoline Thiophen Sulfur compound Thiazole pNP Dimethoxyphenyl
Pyrazoline-Thiazole-Cpd3g Pyrazole Pyrazoline Thiophen Sulfur compound Thiazole Dimethoxyphenyl Cyanide
Thieno-Oxazepine-Cpd14 ACHE Multitarget Azepane Sulfur compound Thiophen
Benzothiophene-3-boronic-acid Sulfur compound Thiophen Boron compound
Methylthiophen-tacrine-Amine-cpd5m ACHE BCHE Multitarget NMDA-Ligand Derivative of Tacrine Acridine Sulfur compound Thiophen
Resveratrol-carbamate-cpd7 BCHE Carbamate Sulfur compound Multitarget Antioxidant Thiophen
Resveratrol-carbamate-cpd13 BCHE Carbamate Sulfur compound Multitarget Antioxidant Thiophen
Resveratrol-carbamate-cpd6 BCHE Carbamate Sulfur compound Multitarget Antioxidant Thiophen
Resveratrol-carbamate-cpdF BCHE Carbamate Sulfur compound Multitarget Antioxidant Thiophen Morpholine
Tricyclic-cyclohepta-thiophene-cpd9 ACHE Sulfur compound Oxazine Thiophen
Duloxetine BCHE Drug Multitarget Sodium:neurotransmitter symporter Naphthalen Sulfur compound Thiophen
Nitrophenyl-thiophen-morpholinyl-phenyl-pyrazoline-2l ACHE Sulfur compound Pyrazole Morpholine Thiophen Pyrazoline
Trifluoromethyl-thiophene-boronic-acid 6_AlphaBeta_hydrolase CarbLipBact_1 Trifluoro Boron compound Sulfur compound Thiophen
Homocysteine-thiolactone ACHE Valacyclovir-hydrolase Carb_B_Chordata Natural Sulfur compound Not AlphaBeta Hydrolase target Thiophen
Fluoropezil ACHE Multitarget Derivative of Donepezil Sulfur compound anti-tau-aggregation Antioxidant Thiophen
N-methyl-4,5-dihydronaphtho[1,2-b]thiophene-2-carboxamide Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur compound Carboxamide Thiophen
4,5-Dihydronaphtho[1,2-b]thiophene-2-carboxylic-acid Pectinacetylesterase-Notum Thiophen Sulfur compound
Methyl-4H-thieno[3,2-c]chromene-2-carboxylic-acid Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur compound Chromen Thiophen
CHEMBL3233609-S0K-3WKD Epoxide_hydrolase Carboxamide Sulfur compound Morpholine Thiophen
CHEMBL4644372 Epoxide_hydrolase LTA4-hydrolase-inhibitor Multitarget Sulfur compound Piperidine Thiophen
CHEMBL1375713 Epoxide_hydrolase Sulfur compound Thiophen
CHEMBL4465514 Epoxide_hydrolase Piperidine Carboxamide Sulfur compound Thiophen
I3-AG85 A85-Mycolyl-transferase Cyanide Sulfur compound Thiophen
ZINC02141756 Carb_B_Chordata Trifluoro Sulfur compound Thiophen Hydrazinylidene
Quinazolin-carbamate-2p BCHE Quinazoline Carbamate Sulfur compound Thiophen