Benzyl-phenyl-cyclopropylcarbonylamino-thiazole-carboxamide-Cpd6l
AChE IC50 of 0.079 +/- 0.16 microM
General
Type : Carboxamide, Thiazole, Cyclopropyl, Sulfur Compound
Chemical_Nomenclature : N-benzyl-N-phenyl-2-(cyclopropylcarbonylamino)-1,3-thiazole-4-carboxamide
Canonical SMILES : O=C(N(CC1=CC=CC=C1)C2=CC=CC=C2)C3=CSC(=N3)NC(=O)C4CC4
InChI : InChI=1S\/C21H19N3O2S\/c25-19(16-11-12-16)23-21-22-18(14-27-21)20(26)24(17-9-5-2-6-10-17)13-15-7-3-1-4-8-15\/h1-10,14,16H,11-13H2,(H,22,23,25)
InChIKey : PEEBTPCELMQWMD-UHFFFAOYSA-N
Other name(s) : Compound 6l || N-Benzyl-N-phenyl-2-(cyclobutyrylamino)-1,3-thiazole-4-carboxamide
Target
Families : Benzyl-phenyl-cyclopropylcarbonylamino-thiazole-carboxamide-Cpd6l ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Synthesis and Characterization of Thiazole Derivatives as Cholinesterase Inhibitors - Zhang_2025_ChemistrySelect_10_e202500051 |
| Author(s) : Zhang Z-Y , Han S-T , Mingyu W , Zien Y , Hu P-h , He R , Cao Y-Y , Shi D-H |
| Ref : ChemistrySelect , 10 :e202500051 , 2025 |
| Abstract : |
| PubMedSearch : Zhang_2025_ChemistrySelect_10_e202500051 |
| PubMedID: |