Bromophenyl-hydrazineylidene-methyl-fluoro-indole-CpdK5
IC50 AChE 27.26 nM; IC50 BChE 34.09 nM; Ki AChE 13.08 +/- 1.79 nM; Ki BChE 5.28 +/- 1.05 nM
General
Type : Hydrazide, Hydrazinylidene, Indole
Chemical_Nomenclature : 3-((2-(3-bromophenyl)hydrazineylidene)methyl)-5-fluoro-1H-indole
Canonical SMILES : C1(=C[N]C2=CC=C(C=C12)F)C=NNC3=CC(=CC=C3)Br
InChI : InChI=1S\/C15H11BrFN3\/c16-11-2-1-3-13(6-11)20-19-9-10-8-18-15-5-4-12(17)7-14(10)15\/h1-9,18,20H
InChIKey : OSWFKFOZIOUENZ-UHFFFAOYSA-N
Other name(s) : Compound K5
Target
Families : Bromophenyl-hydrazineylidene-methyl-fluoro-indole-CpdK5 ligand of proteins in family
ACHE
BCHE
Protein :
human-ACHE
human-BCHE
References (1)
| Title : Synthesis and characterization of novel 5-fluoroindolylmethylene hydrazone derivatives as schiff base compounds: In vitro and in silico evaluation as potential cholinesterase (AChE and BChE) inhibitors, - Koprulu_2026_J.Indian.Chem.Soc_103_102484 |
| Author(s) : Koprulu C , Faydali N , Muhammed MT , Dilek E , Kucukoglu K , Sirinzade H |
| Ref : J Indian Chem Soc , 103 :102484 , 2026 |
| Abstract : |
| PubMedSearch : Koprulu_2026_J.Indian.Chem.Soc_103_102484 |
| PubMedID: |