CHEMBL2376211
Not very specific MAGL IC50 0.028 microM; FAAH IC50 0.012 microM
General
Type : Tetrazol, Carboxamide, Phenoxyphenyl
Chemical_Nomenclature : N,N-dimethyl-5-(4-phenoxyphenyl)tetrazole-2-carboxamide
Canonical SMILES : CN(C)C(=O)N1N=C(N=N1)C2=CC=C(C=C2)OC3=CC=CC=C3
InChI : InChI=1S\/C16H15N5O2\/c1-20(2)16(22)21-18-15(17-19-21)12-8-10-14(11-9-12)23-13-6-4-3-5-7-13\/h3-11H,1-2H3
InChIKey : QVDHPSYKBHTKDV-UHFFFAOYSA-N
Other name(s) : SCHEMBL21775389 || BDBM50432853 || Compound 16
MW : 309.32
Formula : C16H15N5O2
CAS_number :
PubChem : 72197623
UniChem : QVDHPSYKBHTKDV-UHFFFAOYSA-N
Target
Families : CHEMBL2376211 ligand of proteins in family
Monoglyceridelipase_lysophospholip
Protein :
human-MGLL
References (1)
| Title : (4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) - Holtfrerich_2013_Eur.J.Med.Chem_63C_64 |
| Author(s) : Holtfrerich A , Hanekamp W , Lehr M |
| Ref : Eur Journal of Medicinal Chemistry , 63C :64 , 2013 |
| Abstract : |
| PubMedSearch : Holtfrerich_2013_Eur.J.Med.Chem_63C_64 |
| PubMedID: 23455058 |