Chloro-indol-methoxybenzyl-ethan-amine
IC50 AgAChE1 0.4 (0.210.60) microM; IC50 hAChE 62 (5471) microM; S.R 155
General
Type : Indole
Chemical_Nomenclature : 2-(5-Chloro-1H-indol-3-yl)-N-(2-methoxybenzyl)ethan-1-amine hydrochloride
Canonical SMILES : C1=CC(=C(C=C1)CNCCC2=C[N]C3=CC=C(C=C23)Cl)OC
InChI : InChI=1S\/C18H19ClN2O\/c1-22-18-5-3-2-4-14(18)11-20-9-8-13-12-21-17-7-6-15(19)10-16(13)17\/h2-7,10,12,20-21H,8-9,11H2,1H3
InChIKey : GYBYEYSMZJJVTF-UHFFFAOYSA-N
Other name(s) : Compound 18
Target
Families : Chloro-indol-methoxybenzyl-ethan-amine ligand of proteins in family
ACHE
Protein :
anoga-ACHE1
References (1)
| Title : Potent and selective indole-based inhibitors targeting disease-transmitting mosquitoes - Rajeshwari_2025_RSC.Med.Chem__ |
| Author(s) : Rajeshwari R , Duvauchelle V , Lindgren C , Stangner K , Knutsson S , Forsgren N , Ekstrom F , Kamau L , Linusson A |
| Ref : RSC Med Chem , : , 2025 |
| Abstract : |
| PubMedSearch : Rajeshwari_2025_RSC.Med.Chem__ |
| PubMedID: 41551022 |
| Gene_locus related to this paper: aedae-ACHE1 , anoga-ACHE1 , human-ACHE , mouse-ACHE |