Type : Derivative of Evodiamine, Natural, beta-carboline, Not A\/B H target, Multitarget
Chemical_Nomenclature : (1S)-21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15,17,19-heptaen-14-one
Canonical SMILES : CN1C2C3=C(CCN2C(=O)C4=CC=CC=C41)C5=CC=CC=C5N3
InChI : InChI=1S\/C19H17N3O\/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22\/h2-9,18,20H,10-11H2,1H3\/t18-\/m0\/s1
InChIKey : TXDUTHBFYKGSAH-SFHVURJKSA-N
Other name(s) : d-Evodiamine, (+)-Evodiamine, UNII-C01825BVNL, CHEBI:4948, CHEMBL463165, DTXSID10966123, ZINC898159
MW : 303.4
Formula : C19H17N3O
CAS_number : 518-17-2
PubChem : 442088
UniChem : TXDUTHBFYKGSAH-SFHVURJKSA-N
Families : Evodiamine ligand of proteins in family
BCHE
Title : Identification of a neuroprotective and selective butyrylcholinesterase inhibitor derived from the natural alkaloid evodiamine - Huang_2014_Eur.J.Med.Chem_81C_15 |
Author(s) : Huang G , Kling B , Darras FH , Heilmann J , Decker M |
Ref : Eur Journal of Medicinal Chemistry , 81C :15 , 2014 |
PubMedID: 24819955 |
Title : Novel inhibitors of acetyl- and butyrylcholinesterase derived from the alkaloids dehydroevodiamine and rutaecarpine - Decker_2005_Eur.J.Med.Chem_40_305 |
Author(s) : Decker M |
Ref : Eur Journal of Medicinal Chemistry , 40 :305 , 2005 |
PubMedID: 15725500 |