Serine Hydrolase probe consisting of a tag linked to a fluorophosphonate (FP) group, which specifically and covalently labels serines of enzymatically active serine hydrolases. ABPP-Probe (activity based protein profiling probe)
Type : Organophosphate, ABPP-Probe, Biotin derivative
Chemical_Nomenclature : Ethyl (10-(6-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)hexanamido)decyl)phosphonofluoridate
Canonical SMILES : CCO[P](=O)(CCCCCCCCCCN(C(=O)CCCCC[C@@H]1[C@@H](N(C(=O)N1[H])[H])C)[H])F
InChI : InChI=1S\/C22H43FN3O4P\/c1-3-30-31(23,29)18-14-9-7-5-4-6-8-13-17-24-21(27)16-12-10-11-15-20-19(2)25-22(28)26-20\/h19-20H,3-18H2,1-2H3,(H,24,27)(H2,25,26,28)\/t19-,20+,31?\/m0\/s1
InChIKey : AKIGUFDWVLQSPA-LVQXAQMUSA-N
Other name(s) : ActivX Desthiobiotin-FP, ActivX DTB-FP, DTB-FP
MW : 463.57
Formula : C22H43FN3O4P
CAS_number : 1811556-65-6
PubChem : 145710413
UniChem : AKIGUFDWVLQSPA-LVQXAQMUSA-N
Families : FP-Desthiobiotin ligand of proteins in family
LIDHydrolase
Title : Investigating pH Effects on the Enzymes Catalyzing Polysorbate Degradation by Activity-Based Protein Profiling - Dehghani_2023_J.Pharm.Sci__ |
Author(s) : Dehghani A , Binder F , Zorn M , Feigler A , Fischer KI , Felix MN , Happersberger P , Reisinger B |
Ref : J Pharm Sci , : , 2023 |
PubMedID: 37758159 |
Title : Novel lipid droplet-associated serine hydrolase regulates macrophage cholesterol mobilization - Goo_2014_Arterioscler.Thromb.Vasc.Biol_34_386 |
Author(s) : Goo YH , Son SH , Kreienberg PB , Paul A |
Ref : Arterioscler Thromb Vasc Biol , 34 :386 , 2014 |
PubMedID: 24357060 |
Gene_locus related to this paper: human-LDAH |