Family: LIDHydrolase

Block: X

Parent Family: Abhydrolase_6


Family LIDHydrolase DUF2305 UPF0554 This family of proteins is conserved from plants to humans. The function is unknown. A lipid droplet hydrolase LD-associated hydrolase (LDAH) (C2orf43) with weak in vitro cholesterol hydrolase was described by Goo et al. The name DUF_2305 was replaced by LIDHydrolase


Interpro : IPR019363 Lipid droplet-associated hydrolase DUF2305


Pdoc : No Pdoc

Pfam : PF10230 LIDHydrolase DUF2305

Prints : No Print

EC Number : No EC Number


Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

No structure scheme yet for this family

Genes Proteins in LIDHydrolase family (102)

Fragments of genes in LIDHydrolase family (10)

No fragment of genes

Substrates in LIDHydrolase family (1)

Inhibitors in LIDHydrolase family (1)

References (4)

Title : Saccharomyces cerevisiae lipid droplet associated enzyme Ypr147cp shows both TAG lipase and ester hydrolase activities - Manda_2018_J.Gen.Appl.Microbiol_64_76
Author(s) : Manda NK , Thunuguntla VBSC , Bokka CS , Singh BJ
Ref : J Gen Appl Microbiol , 64 :76 , 2018
PubMedID: 29491250
Gene_locus related to this paper: aspnc-a2qgm6 , yeast-YPR147C

Title : Mice lacking lipid droplet-associated hydrolase, a gene linked to human prostate cancer, have normal cholesterol ester metabolism - Kory_2017_J.Lipid.Res_58_226
Author(s) : Kory N , Grond S , Kamat SS , Li Z , Krahmer N , Chitraju C , Zhou P , Frohlich F , Semova I , Ejsing C , Zechner R , Cravatt BF , Farese RV, Jr. , Walther TC
Ref : J Lipid Res , 58 :226 , 2017
PubMedID: 27836991
Gene_locus related to this paper: human-LDAH , mouse-Ldah

Title : Novel lipid droplet-associated serine hydrolase regulates macrophage cholesterol mobilization - Goo_2014_Arterioscler.Thromb.Vasc.Biol_34_386
Author(s) : Goo YH , Son SH , Kreienberg PB , Paul A
Ref : Arterioscler Thromb Vasc Biol , 34 :386 , 2014
PubMedID: 24357060
Gene_locus related to this paper: human-LDAH

Title : Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies - Wan_2007_FASEB.J_21_167
Author(s) : Wan HC , Melo RC , Jin Z , Dvorak AM , Weller PF
Ref : FASEB Journal , 21 :167 , 2007
PubMedID: 17135363
Gene_locus related to this paper: human-LDAH