Fmoc-prolyl-pyrrolidine-2-nitrile
General
Type : Peptide, Fluoren, Pyrrolidine, Cyanide
Chemical_Nomenclature : 9H-fluoren-9-ylmethyl (2S)-2-(2-cyanopyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate
Canonical SMILES : C1C[C@H](N(C1)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)N5CCCC5C#N
InChI : InChI=1S\/C25H25N3O3\/c26-15-17-7-5-13-27(17)24(29)23-12-6-14-28(23)25(30)31-16-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22\/h1-4,8-11,17,22-23H,5-7,12-14,16H2\/t17?,23-\/m0\/s1
InChIKey : VXHXMCNCCQPZOQ-VXLWULRPSA-N
Other name(s) : Fmoc-Pro-PyrrCN
MW : 415.5
Formula : C25H25N3O3
CAS_number :
PubChem : 54415804
UniChem : VXHXMCNCCQPZOQ-VXLWULRPSA-N
Target
Families : Fmoc-prolyl-pyrrolidine-2-nitrile ligand of proteins in family
S9N_PPCE_Peptidase_S9
Protein :
human-PREP
References (3)
| Title : Prolyl oligopeptidase is involved in release of the antifibrotic peptide Ac-SDKP - Cavasin_2004_Hypertension_43_1140 |
| Author(s) : Cavasin MA , Rhaleb NE , Yang XP , Carretero OA |
| Ref : Hypertension , 43 :1140 , 2004 |
| Abstract : |
| PubMedSearch : Cavasin_2004_Hypertension_43_1140 |
| PubMedID: 15037553 |
| Gene_locus related to this paper: human-PREP |
| Title : Early prepubertal ontogeny of pulsatile gonadotropin-releasing hormone (GnRH) secretion: I. Inhibitory autofeedback control through prolyl endopeptidase degradation of GnRH - Yamanaka_1999_Endocrinology_140_4609 |
| Author(s) : Yamanaka C , Lebrethon MC , Vandersmissen E , Gerard A , Purnelle G , Lemaitre M , Wilk S , Bourguignon JP |
| Ref : Endocrinology , 140 :4609 , 1999 |
| Abstract : |
| PubMedSearch : Yamanaka_1999_Endocrinology_140_4609 |
| PubMedID: 10499517 |
| Gene_locus related to this paper: human-PREP |
| Title : Inhibition of prolyl oligopeptidase by Fmoc-aminoacylpyrrolidine-2-nitriles - Li_1996_J.Neurochem_66_2105 |
| Author(s) : Li J , Wilk E , Wilk S |
| Ref : Journal of Neurochemistry , 66 :2105 , 1996 |
| Abstract : |
| PubMedSearch : Li_1996_J.Neurochem_66_2105 |
| PubMedID: 8780042 |
| Gene_locus related to this paper: human-PREP |