Imipramine
Imipramine is the prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
General
Type : Adrenergic Uptake Inhibitors, Not A\/B H target, Drug, Azepane, Benzazepin
Chemical_Nomenclature : 10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5propanamine
Canonical SMILES : CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31
InChI : InChI=1S\/C19H24N2\/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21\/h3-6,8-11H,7,12-15H2,1-2H3
InChIKey : BCGWQEUPMDMJNV-UHFFFAOYSA-N
Other name(s) : Imidobenzyle || Antideprin || Dimipressin || Melipramin || Melipramine || Nelipramin || Berkomine || Impramine || Intalpram || imizin
MW : 280.407
Formula : C19H24N2
CAS_number : 50-49-7
PubChem : 3696
UniChem : BCGWQEUPMDMJNV-UHFFFAOYSA-N
Wikipedia : Imipramine
Target
Families : Imipramine ligand of proteins in family
BCHE
References (4)
| Title : Parasympatholytic activity of psychoactive drugs in rat brain mitochondria - Nag_1995_Ind.J.Exp.Biol_33_462 |
| Author(s) : Nag M , Basu PS , Nandi N |
| Ref : Indian Journal of Experimental Biology , 33 :462 , 1995 |
| Abstract : |
| PubMedSearch : Nag_1995_Ind.J.Exp.Biol_33_462 |
| PubMedID: 7590953 |
| Title : Neurochemical and histopathologic alterations characteristic of Pick's disease in a non-demented individual - Sparks_1994_J.Neuropathol.Exp.Neurol_53_37 |
| Author(s) : Sparks DL , Danner FW , Davis DG , Hackney C , Landers T , Coyne CM |
| Ref : Journal of Neuropathology & Experimental Neurology , 53 :37 , 1994 |
| Abstract : |
| PubMedSearch : Sparks_1994_J.Neuropathol.Exp.Neurol_53_37 |
| PubMedID: 8301318 |
| Title : A peptidase activity exhibited by human serum pseudocholinesterase - Boopathy_1987_Eur.J.Biochem_162_191 |
| Author(s) : Boopathy R , Balasubramanian AS |
| Ref : European Journal of Biochemistry , 162 :191 , 1987 |
| Abstract : |
| PubMedSearch : Boopathy_1987_Eur.J.Biochem_162_191 |
| PubMedID: 3545820 |
| Title : Chemical modification of the bifunctional human serum pseudocholinesterase. Effect on the pseudocholinesterase and aryl acylamidase activities - Boopathy_1985_Eur.J.Biochem_151_351 |
| Author(s) : Boopathy R , Balasubramanian AS |
| Ref : European Journal of Biochemistry , 151 :351 , 1985 |
| Abstract : |
| PubMedSearch : Boopathy_1985_Eur.J.Biochem_151_351 |
| PubMedID: 2863142 |