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Azepane

General

Azepane is a cyclic secondary amine with the formula (CH2)6NH. It is a precursor to several drugs and pesticides (also Azepine)
Inhibitor Main targeted enzyme families Type Structure
Furanoazepinone-isobenzofurandione-cpd5n ACHE Azepane
CHEMBL5425833-CpdG1 Epoxide_hydrolase Urea derivative Diazepan Azepane Piperidine Adamantyl
Cyclohexylaminopropyl-Kenpaullone-carboxamide-Cpd18o GSK-3 kinase inhibitor Multitarget Indole Carboxamide Azepane
AChE-IN-14 ACHE BCHE Multitarget Azepane Chromen Histamine-Receptor3-H3-Antagonist
Diazepine-carbamate-cpd6b BCHE Azepane Carbamate Benzodiazepin Diazepan
Thieno-Oxazepine-Cpd14 ACHE Multitarget Azepane Sulfur Compound Thiophen
Galantamine-benzylpyridine-C2 ACHE BCHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Piperidine Pyridine Benzazepin Azepane
CHDA ACHE Derivative of Tacrine Acridine Azepane anti-Abeta-aggregation Multitarget Organochlorine
6-(2-phenylethyl)-THAI-12b BCHE Indole Azepane
6-(4-4-phenethylpiperazin-1-yl)heptyl-THAI-14d BCHE Indole Azepane Piperazine Multitarget Alkyl linked bis-ligand anti-Abeta-aggregation
Indol-carbodithioate-azepane Lipase_3 Indole Isoindole Azepane Sulfur Compound
JM-20 ACHE Benzodiazepin Not AlphaBeta Hydrolase target Pyridine Multitarget 2-nitrophenyl Azepane
6XTA-cpd18 BCHE Derivative of Tryptophan Indole Azepane
SR-3420 CGI-58_ABHD5_ABHD4 Urea derivative Sulfur Compound Benzothiazepine Azepane Trifluoro
SR-4995 CGI-58_ABHD5_ABHD4 Urea derivative Sulfur Compound Benzothiazepine Azepane
18-E100 ACHE BCHE Cholinesterase Multitarget Azepane Histamine-Receptor3-H3-Antagonist Organochlorine
N-piperidinopropylgalanthamine ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Piperidine Benzazepin Azepane
N-saccharinohexylgalanthamine ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Sulfur Compound Benzazepin Azepane
bis9-(-)-nor-meptazinol ACHE Alkyl linked bis-ligand Azepane
Diazepan-AJH DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Cyclic-Hydrazine-Derivative DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Diazepanone-Analog-18 DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Diazepanone-Analog-1 DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Memagal ACHE Multitarget Derivative of Galanthamine NMDA-Ligand Alkyl linked bis-ligand Benzazepin Azepane
ARN14140-doubleboundlink ACHE Adamantyl Alkyl linked bis-ligand Multitarget Derivative of Galanthamine NMDA-Ligand Benzazepin Azepane
ARN14140 ACHE Adamantyl Multitarget Derivative of Galanthamine NMDA-Ligand Alkyl linked bis-ligand Benzazepin Azepane
Molinate Carbamate Thiocarbamate Herbicide Sulfur Compound Azepane Not AlphaBeta Hydrolase target
W22 Bacterial_esterase Benzodiazepin Diazepan Azepane
CI-1002 ACHE Derivative of Tacrine Acridine Muscarinic antagonist Quinazoline Azepane Organochlorine
Memogain ACHE Carb_B_Chordata Derivative of Galanthamine Alkaloid Benzoate Natural_modified Benzazepin Azepane
Phthalimido-Galanthaminium-4d ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Isoindole Indole Phthalimido Benzazepin Azepane
Phthalimido-Galanthaminium-8d ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Isoindole Indole Phthalimido Benzazepin Azepane
Galanthaminium ACHE Derivative of Galanthamine Alkaloid Natural_modified Benzazepin Azepane
Sanguinine ACHE Derivative of Galanthamine Natural Alkaloid Benzazepin Azepane
Galanthamine ACHE Derivative of Galanthamine Natural Alkaloid Drug Benzazepin Azepane Multitarget Nicotinic agonist Azocine
Bis-galanthamine ACHE Derivative of Galanthamine Alkaloid Alkyl linked bis-ligand Benzazepin Azepane Natural_modified
Imipramine BCHE Adrenergic Uptake Inhibitors Not AlphaBeta Hydrolase target Drug Azepane Benzazepin
P11149 BCHE ACHE Adamantyl Derivative of Galanthamine Alkaloid Benzazepin Azepane Natural_modified Organochlorine
BChE-IN-9 BCHE Azepane
Furanoazepinone-isobenzofurandione-cpd5n ACHE Azepane
CHEMBL5425833-CpdG1 Epoxide_hydrolase Urea derivative Diazepan Azepane Piperidine Adamantyl
Cyclohexylaminopropyl-Kenpaullone-carboxamide-Cpd18o GSK-3 kinase inhibitor Multitarget Indole Carboxamide Azepane
AChE-IN-14 ACHE BCHE Multitarget Azepane Chromen Histamine-Receptor3-H3-Antagonist
Diazepine-carbamate-cpd6b BCHE Azepane Carbamate Benzodiazepin Diazepan
Thieno-Oxazepine-Cpd14 ACHE Multitarget Azepane Sulfur compound Thiophen
Galantamine-benzylpyridine-C2 ACHE BCHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Piperidine Pyridine Benzazepin Azepane
CHDA ACHE Derivative of Tacrine Acridine Azepane anti-Abeta-aggregation Multitarget Organochlorine
6-(2-phenylethyl)-THAI-12b BCHE Indole Azepane
6-(4-4-phenethylpiperazin-1-yl)heptyl-THAI-14d BCHE Indole Azepane Piperazine Multitarget Alkyl linked bis-ligand anti-Abeta-aggregation
Indol-carbodithioate-azepane Lipase_3 Indole Isoindole Azepane Sulfur compound
JM-20 ACHE Benzodiazepin Not AlphaBeta Hydrolase target Pyridine Multitarget 2-nitrophenyl Azepane
6XTA-cpd18 BCHE Derivative of Tryptophan Indole Azepane
SR-3420 CGI-58_ABHD5_ABHD4 Urea derivative Sulfur compound Benzothiazepine Azepane Trifluoro
SR-4995 CGI-58_ABHD5_ABHD4 Urea derivative Sulfur compound Benzothiazepine Azepane
18-E100 ACHE BCHE Cholinesterase Multitarget Azepane Histamine-Receptor3-H3-Antagonist Organochlorine
N-piperidinopropylgalanthamine ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Piperidine Benzazepin Azepane
N-saccharinohexylgalanthamine ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Sulfur compound Benzazepin Azepane
bis9-(-)-nor-meptazinol ACHE Alkyl linked bis-ligand Azepane
Diazepan-AJH DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Cyclic-Hydrazine-Derivative DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Diazepanone-Analog-18 DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Diazepanone-Analog-1 DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Memagal ACHE Multitarget Derivative of Galanthamine NMDA-Ligand Alkyl linked bis-ligand Benzazepin Azepane
ARN14140-doubleboundlink ACHE Adamantyl Alkyl linked bis-ligand Multitarget Derivative of Galanthamine NMDA-Ligand Benzazepin Azepane
ARN14140 ACHE Adamantyl Multitarget Derivative of Galanthamine NMDA-Ligand Alkyl linked bis-ligand Benzazepin Azepane
Molinate Carbamate Thiocarbamate Herbicide Sulfur compound Azepane Not AlphaBeta Hydrolase target
W22 Bacterial_esterase Benzodiazepin Diazepan Azepane
CI-1002 ACHE Derivative of Tacrine Acridine Muscarinic antagonist Quinazoline Azepane Organochlorine
Memogain ACHE Carb_B_Chordata Derivative of Galanthamine Alkaloid Benzoate Natural_modified Benzazepin Azepane
Phthalimido-Galanthaminium-4d ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Isoindole Indole Phthalimido Benzazepin Azepane
Phthalimido-Galanthaminium-8d ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Isoindole Indole Phthalimido Benzazepin Azepane
Galanthaminium ACHE Derivative of Galanthamine Alkaloid Natural_modified Benzazepin Azepane
Sanguinine ACHE Derivative of Galanthamine Natural Alkaloid Benzazepin Azepane
Galanthamine ACHE Derivative of Galanthamine Natural Alkaloid Drug Benzazepin Azepane Multitarget Nicotinic agonist Azocine
Bis-galanthamine ACHE Derivative of Galanthamine Alkaloid Alkyl linked bis-ligand Benzazepin Azepane Natural_modified
Imipramine BCHE Adrenergic Uptake Inhibitors Not AlphaBeta Hydrolase target Drug Azepane Benzazepin
P11149 BCHE ACHE Adamantyl Derivative of Galanthamine Alkaloid Benzazepin Azepane Natural_modified Organochlorine
BChE-IN-9 BCHE Azepane
Furanoazepinone-isobenzofurandione-cpd5n ACHE Azepane
CHEMBL5425833-CpdG1 Epoxide_hydrolase Urea derivative Diazepan Azepane Piperidine Adamantyl
Cyclohexylaminopropyl-Kenpaullone-carboxamide-Cpd18o GSK-3 kinase inhibitor Multitarget Indole Carboxamide Azepane
AChE-IN-14 ACHE BCHE Multitarget Azepane Chromen Histamine-Receptor3-H3-Antagonist
Diazepine-carbamate-cpd6b BCHE Azepane Carbamate Benzodiazepin Diazepan
Thieno-Oxazepine-Cpd14 ACHE Multitarget Azepane Sulfur compound Thiophen
Galantamine-benzylpyridine-C2 ACHE BCHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Piperidine Pyridine Benzazepin Azepane
CHDA ACHE Derivative of Tacrine Acridine Azepane anti-Abeta-aggregation Multitarget Organochlorine
6-(2-phenylethyl)-THAI-12b BCHE Indole Azepane
6-(4-4-phenethylpiperazin-1-yl)heptyl-THAI-14d BCHE Indole Azepane Piperazine Multitarget Alkyl linked bis-ligand anti-Abeta-aggregation
Indol-carbodithioate-azepane Lipase_3 Indole Isoindole Azepane Sulfur compound
JM-20 ACHE Benzodiazepin Not AlphaBeta Hydrolase target Pyridine Multitarget 2-nitrophenyl Azepane
6XTA-cpd18 BCHE Derivative of Tryptophan Indole Azepane
SR-3420 CGI-58_ABHD5_ABHD4 Urea derivative Sulfur compound Benzothiazepine Azepane Trifluoro
SR-4995 CGI-58_ABHD5_ABHD4 Urea derivative Sulfur compound Benzothiazepine Azepane
18-E100 ACHE BCHE Cholinesterase Multitarget Azepane Histamine-Receptor3-H3-Antagonist Organochlorine
N-piperidinopropylgalanthamine ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Piperidine Benzazepin Azepane
N-saccharinohexylgalanthamine ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Sulfur compound Benzazepin Azepane
bis9-(-)-nor-meptazinol ACHE Alkyl linked bis-ligand Azepane
Diazepan-AJH DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Cyclic-Hydrazine-Derivative DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Diazepanone-Analog-18 DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Diazepanone-Analog-1 DPP4N_Peptidase_S9 Trifluoro Diazepan Azepane
Memagal ACHE Multitarget Derivative of Galanthamine NMDA-Ligand Alkyl linked bis-ligand Benzazepin Azepane
ARN14140-doubleboundlink ACHE Adamantyl Alkyl linked bis-ligand Multitarget Derivative of Galanthamine NMDA-Ligand Benzazepin Azepane
ARN14140 ACHE Adamantyl Multitarget Derivative of Galanthamine NMDA-Ligand Alkyl linked bis-ligand Benzazepin Azepane
Molinate Carbamate Thiocarbamate Herbicide Sulfur compound Azepane Not AlphaBeta Hydrolase target
W22 Bacterial_esterase Benzodiazepin Diazepan Azepane
CI-1002 ACHE Derivative of Tacrine Acridine Muscarinic antagonist Quinazoline Azepane Organochlorine
Memogain ACHE Carb_B_Chordata Derivative of Galanthamine Alkaloid Benzoate Natural_modified Benzazepin Azepane
Phthalimido-Galanthaminium-4d ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Isoindole Indole Phthalimido Benzazepin Azepane
Phthalimido-Galanthaminium-8d ACHE Derivative of Galanthamine Alkaloid Natural_modified Alkyl linked bis-ligand Isoindole Indole Phthalimido Benzazepin Azepane
Galanthaminium ACHE Derivative of Galanthamine Alkaloid Natural_modified Benzazepin Azepane
Sanguinine ACHE Derivative of Galanthamine Natural Alkaloid Benzazepin Azepane
Galanthamine ACHE Derivative of Galanthamine Natural Alkaloid Drug Benzazepin Azepane Multitarget Nicotinic agonist Azocine
Bis-galanthamine ACHE Derivative of Galanthamine Alkaloid Alkyl linked bis-ligand Benzazepin Azepane Natural_modified
Imipramine BCHE Adrenergic Uptake Inhibitors Not AlphaBeta Hydrolase target Drug Azepane Benzazepin
P11149 BCHE ACHE Adamantyl Derivative of Galanthamine Alkaloid Benzazepin Azepane Natural_modified Organochlorine
BChE-IN-9 BCHE Azepane