Indol-methoxybenzyl-ethan-amine
IC50 AgAChE1 1.6 (1.32.0) microM; IC50 AaAChE1 1.1 (0.91.4) microM; IC50 hAChE 70 (39330) microM; S.R 44
General
Type : Indole
Chemical_Nomenclature : 2-(1H-indol-3-yl)-N-(2-methoxybenzyl)ethan-1-amine || 2-(1H-indol-3-yl)-N-[(2-methoxyphenyl)methyl]ethanamine
Canonical SMILES : COC1=CC=CC=C1CNCCC2=CNC3=CC=CC=C32
InChI : InChI=1S\/C18H20N2O\/c1-21-18-9-5-2-6-15(18)12-19-11-10-14-13-20-17-8-4-3-7-16(14)17\/h2-9,13,19-20H,10-12H2,1H3
InChIKey : HJCSKFSDXDPIKM-UHFFFAOYSA-N
Other name(s) : [2-(1H-indol-3-yl)ethyl][(2-methoxyphenyl)methyl]amine || 2-(1H-indol-3-yl)-N-[(2-methoxyphenyl)methyl]ethanamine || CHEMBRDG-BB 5555063 || Compound 8
MW : 280.4
Formula : C18H20N2O
CAS_number : 418781-81-4
PubChem : 1988048
UniChem : HJCSKFSDXDPIKM-UHFFFAOYSA-N
Target
Families : Indol-methoxybenzyl-ethan-amine ligand of proteins in family
ACHE
Structure :
9SND
Protein :
mouse-ACHE
human-ACHE
anoga-ACHE1
aedae-ACHE1
References (1)
| Title : Potent and selective indole-based inhibitors targeting disease-transmitting mosquitoes - Rajeshwari_2025_RSC.Med.Chem__ |
| Author(s) : Rajeshwari R , Duvauchelle V , Lindgren C , Stangner K , Knutsson S , Forsgren N , Ekstrom F , Kamau L , Linusson A |
| Ref : RSC Med Chem , : , 2025 |
| Abstract : |
| PubMedSearch : Rajeshwari_2025_RSC.Med.Chem__ |
| PubMedID: 41551022 |
| Gene_locus related to this paper: aedae-ACHE1 , anoga-ACHE1 , human-ACHE , mouse-ACHE |