JCP251

General

Type : Coumarin, Chromen

Chemical_Nomenclature : 7-amino-4-chloro-3-methoxyisochromen-1-one

Canonical SMILES : COC1=C(C2=C(C=C(C=C2)N)C(=O)O1)Cl

InChI : InChI=1S\/C10H8ClNO3\/c1-14-10-8(11)6-3-2-5(12)4-7(6)9(13)15-10\/h2-4H,12H2,1H3

InChIKey : AMDGKLWVCUXONP-UHFFFAOYSA-N

Other name(s) : JLK 6  ||  jlk6  ||  JCP 251


MW : 225.63

Formula : C10H8ClNO3

CAS_number : 62252-26-0

PubChem : 3803

UniChem : AMDGKLWVCUXONP-UHFFFAOYSA-N

Target

Families : JCP251 ligand of proteins in family
Hormone-sensitive_lipase_like A85-EsteraseD-FGH

Protein :
staau-MW2456 staau-SA2422

References (2)

Title : Identification of highly selective covalent inhibitors by phage display - Chen_2021_Nat.Biotechnol_39_490
Author(s) : Chen S , Lovell S , Lee S , Fellner M , Mace PD , Bogyo M
Ref : Nat Biotechnol , 39 :490 , 2021
Abstract :
PubMedSearch : Chen_2021_Nat.Biotechnol_39_490
PubMedID: 33199876
Gene_locus related to this paper: staau-SA2422

Title : Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP) - Lentz_2018_Nat.Chem.Biol_14_609
Author(s) : Lentz CS , Sheldon JR , Crawford LA , Cooper R , Garland M , Amieva MR , Weerapana E , Skaar EP , Bogyo M
Ref : Nat Chemical Biology , 14 :609 , 2018
Abstract :
PubMedSearch : Lentz_2018_Nat.Chem.Biol_14_609
PubMedID: 29769740
Gene_locus related to this paper: staau-MW2456 , staau-SA2422