JCP251
General
Chemical_Nomenclature : 7-amino-4-chloro-3-methoxyisochromen-1-one
Canonical SMILES : COC1=C(C2=C(C=C(C=C2)N)C(=O)O1)Cl
InChI : InChI=1S\/C10H8ClNO3\/c1-14-10-8(11)6-3-2-5(12)4-7(6)9(13)15-10\/h2-4H,12H2,1H3
InChIKey : AMDGKLWVCUXONP-UHFFFAOYSA-N
Other name(s) : JLK 6 || jlk6 || JCP 251
MW : 225.63
Formula : C10H8ClNO3
CAS_number : 62252-26-0
PubChem : 3803
UniChem : AMDGKLWVCUXONP-UHFFFAOYSA-N
Target
Families : JCP251 ligand of proteins in family
Hormone-sensitive_lipase_like
A85-EsteraseD-FGH
Protein :
staau-MW2456
staau-SA2422
References (2)
| Title : Identification of highly selective covalent inhibitors by phage display - Chen_2021_Nat.Biotechnol_39_490 |
| Author(s) : Chen S , Lovell S , Lee S , Fellner M , Mace PD , Bogyo M |
| Ref : Nat Biotechnol , 39 :490 , 2021 |
| Abstract : |
| PubMedSearch : Chen_2021_Nat.Biotechnol_39_490 |
| PubMedID: 33199876 |
| Gene_locus related to this paper: staau-SA2422 |
| Title : Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP) - Lentz_2018_Nat.Chem.Biol_14_609 |
| Author(s) : Lentz CS , Sheldon JR , Crawford LA , Cooper R , Garland M , Amieva MR , Weerapana E , Skaar EP , Bogyo M |
| Ref : Nat Chemical Biology , 14 :609 , 2018 |
| Abstract : |
| PubMedSearch : Lentz_2018_Nat.Chem.Biol_14_609 |
| PubMedID: 29769740 |
| Gene_locus related to this paper: staau-MW2456 , staau-SA2422 |